A redox-responsive organogel based on a selenium-containing low molecular mass gelator

2020 ◽  
Vol 44 (1) ◽  
pp. 24-28 ◽  
Author(s):  
Haojie Zhang ◽  
Xiuping Lu ◽  
Zhao Chen ◽  
Jianzhong Jiang ◽  
Yukai Chen
Keyword(s):  
Ethyl Acetate ◽  
Molecular Mass ◽  
Active Center ◽  
Redox Active ◽  
Redox Responsive

A redox-responsive low molecular mass gelator (Chol-Se) with selenium as its redox-active center was designed and synthesized. Responsive transformation of Chol-Se in ethyl acetate between the gelation and solution was achieved.

scholarly journals Drawing on biology to inspire molecular design: a redox-responsive MRI probe based on Gd(iii)-nicotinamide

2018 ◽  
Vol 54 (92) ◽  
pp. 12986-12989 ◽  
Author(s):  
Michael Harris ◽  
Jacek L. Kolanowski ◽  
Edward S. O’Neill ◽  
Céline Henoumont ◽  
Sophie Laurent ◽  
...  
Keyword(s):  
Molecular Design ◽  
Biologically Inspired ◽  
Redox Active ◽  
Reversible Redox ◽  
Redox Responsive ◽  
Redox Switch

A novel, reversible redox-active MRI probe, GdNR1, has been developed based on the biologically-inspired nicotinimidium redox switch.

Reversed phase behaviour of high molecular mass polystyrenes in ethyl acetate solvent mixtures

1994 ◽  
Vol 39 (11-12) ◽  
pp. 663-667 ◽  
Author(s):  
R. A. Shalliker ◽  
P. E. Kavanagh ◽  
I. M. Russell
Keyword(s):  
Ethyl Acetate ◽  
Molecular Mass ◽  
Reversed Phase ◽  
High Molecular Mass ◽  
Phase Behaviour ◽  
Solvent Mixtures

Buildup of Redox-Responsive Hybrid from Polyoxometalate and Redox-Active Conducting Oligomer: Its Self-Assemblies with Controllable Morphologies

2017 ◽  
Vol 23 (59) ◽  
pp. 14860-14865 ◽  
Author(s):  
Shan She ◽  
Zehuan Huang ◽  
Panchao Yin ◽  
Aruuhan Bayaguud ◽  
Hongli Jia ◽  
...  
Keyword(s):  
Redox Active ◽  
Redox Responsive

Tyrosine as a redox-active center in electron transfer to ferryl heme in globins

2008 ◽  
Vol 44 (3) ◽  
pp. 274-283 ◽  
Author(s):  
Brandon J. Reeder ◽  
Francesca Cutruzzola ◽  
Maria Giulia Bigotti ◽  
Robert C. Hider ◽  
Michael T. Wilson
Keyword(s):  
Electron Transfer ◽  
Active Center ◽  
Redox Active

Redox-responsive host–guest system using redox-active pillar[5]arene containing one benzoquinone unit

2016 ◽  
Vol 52 (38) ◽  
pp. 6479-6481 ◽  
Author(s):  
Tomoki Ogoshi ◽  
Tomohiro Akutsu ◽  
Yasuo Shimada ◽  
Tada-aki Yamagishi
Keyword(s):  
Redox Active ◽  
Redox Responsive ◽  
Guest System

Pillar[5]arene with one benzoquinone formed weak complex with a guest, while pillar[5]arene containing one hydroquinone strongly captured the guest.

A novel low-molecular-mass gelator with a redox active ferrocenyl group: Tuning gel formation by oxidation

2008 ◽  
Vol 318 (2) ◽  
pp. 397-404 ◽  
Author(s):  
Jing Liu ◽  
Junlin Yan ◽  
Xuanwei Yuan ◽  
Kaiqiang Liu ◽  
Junxia Peng ◽  
...  
Keyword(s):  
Molecular Mass ◽  
Gel Formation ◽  
Ferrocenyl Group ◽  
Redox Active

scholarly journals Characterization of Redox-Responsive LXR-Activating Nanoparticle Formulations in Primary Mouse Macrophages

Molecules ◽  
2019 ◽  
Vol 24 (20) ◽  
pp. 3751 ◽  
Author(s):  
Tyler K. T. Smith ◽  
Zaina Kahiel ◽  
Nicholas D. LeBlond ◽  
Peyman Ghorbani ◽  
Eliya Farah ◽  
...  
Keyword(s):  
Potential Candidate ◽  
Beneficial Effects ◽  
Redox Active ◽  
Primary Mouse ◽  
Mouse Macrophages ◽  
Redox Responsive ◽  
Exposure In Vivo ◽  
Abca1 Protein

Activation of the transcription factor liver X receptor (LXR) has beneficial effects on macrophage lipid metabolism and inflammation, making it a potential candidate for therapeutic targeting in cardiometabolic disease. While small molecule delivery via nanomedicine has promising applications for a number of chronic diseases, questions remain as to how nanoparticle formulation might be tailored to suit different tissue microenvironments and aid in drug delivery. In the current study, we aimed to compare the in vitro drug delivering capability of three nanoparticle (NP) formulations encapsulating the LXR activator, GW-3965. We observed little difference in the base characteristics of standard PLGA-PEG NP when compared to two redox-active polymeric NP formulations, which we called redox-responsive (RR)1 and RR2. Moreover, we also observed similar uptake of these NP into primary mouse macrophages. We used the transcript and protein expression of the cholesterol efflux protein and LXR target ATP-binding cassette A1 (ABCA1) as a readout of GW-3956-induced LXR activation. Following an initial acute uptake period that was meant to mimic circulating exposure in vivo, we determined that although the induction of transcript expression was similar between NPs, treatment with the redox-sensitive RR1 NPs resulted in a higher level of ABCA1 protein. Our results suggest that NP formulations responsive to cellular cues may be an effective tool for targeted and disease-specific drug release.

scholarly journals Iron: The Redox-active Center of Oxidative Stress in Alzheimer Disease

2007 ◽  
Vol 32 (10) ◽  
pp. 1640-1645 ◽  
Author(s):  
Rudy J. Castellani ◽  
Paula I. Moreira ◽  
Gang Liu ◽  
Jon Dobson ◽  
George Perry ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Alzheimer Disease ◽  
Active Center ◽  
Redox Active
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