Backbone-modified oligonucleotides for tuning the cellular uptake behaviour of spherical nucleic acids

2017 ◽  
Vol 5 (3) ◽  
pp. 412-416 ◽  
Author(s):  
Woo Chul Song ◽  
Kyoung-Ran Kim ◽  
Miri Park ◽  
Kyung Eun Lee ◽  
Dae-Ro Ahn
Keyword(s):  
Nucleic Acids ◽  
Cellular Uptake ◽  
Modified Oligonucleotides ◽  
Uptake Efficiency ◽  
Spherical Nucleic Acids ◽  
Cellular Uptake Efficiency

Spherical nucleic acids (SNAs) were prepared using sugar backbone-modified oligonucleotides, and the effects of the oligonucleotides on the cellular uptake efficiency of SNAs were investigated.

scholarly journals The morphology and surface charge-dependent cellular uptake efficiency of upconversion nanostructures revealed by single-particle optical microscopy

2018 ◽  
Vol 9 (23) ◽  
pp. 5260-5269 ◽  
Author(s):  
Di Zhang ◽  
Lin Wei ◽  
Meile Zhong ◽  
Lehui Xiao ◽  
Hung-Wing Li ◽  
...  
Keyword(s):  
Surface Charge ◽  
Optical Microscopy ◽  
Cellular Uptake ◽  
Single Particle ◽  
Cellular Internalization ◽  
Uptake Efficiency ◽  
Size And Shape ◽  
Internalization Process ◽  
Cellular Uptake Efficiency

The cellular uptake efficiency of nanostructures has been demonstrated to be highly dependent on the surface charge, size and shape although the cellular internalization process is still far from being well-understood.

Membrane Microdomain Structures of Liposomes and Their Contribution to the Cellular Uptake Efficiency into HeLa Cells

2016 ◽  
Vol 13 (2) ◽  
pp. 369-378 ◽  
Author(s):  
Yoshinori Onuki ◽  
Yasuko Obata ◽  
Kumi Kawano ◽  
Hiromu Sano ◽  
Reina Matsumoto ◽  
...  
Keyword(s):  
Cellular Uptake ◽  
Hela Cells ◽  
Uptake Efficiency ◽  
Membrane Microdomain ◽  
Cellular Uptake Efficiency

scholarly journals Biocompatible carbon-doped MoSe2 nanoparticles as a highly efficient targeted agent for human renal cell carcinoma

RSC Advances ◽  
2019 ◽  
Vol 9 (20) ◽  
pp. 11567-11575 ◽  
Author(s):  
Li Gao ◽  
Yi-zeng Fan ◽  
Tao-hong Zhang ◽  
Hui-qiu Xu ◽  
Xian-ling Zeng ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Cellular Uptake ◽  
Renal Cell ◽  
Human Renal Cell Carcinoma ◽  
Carbon Doped ◽  
Uptake Efficiency ◽  
High Viability ◽  
Targeted Agent ◽  
Cellular Uptake Efficiency

HK-2 cells have weak cellular uptake efficiency leading to high viability with carbon-doped MoSe2 nanoparticles.

scholarly journals The Impact of Protein Corona Formation on the Macrophage Cellular Uptake and Biodistribution of Spherical Nucleic Acids

Small ◽  
2017 ◽  
Vol 13 (16) ◽  
pp. 1603847 ◽  
Author(s):  
Alyssa B. Chinen ◽  
Chenxia M. Guan ◽  
Caroline H. Ko ◽  
Chad A. Mirkin
Keyword(s):  
Nucleic Acids ◽  
Cellular Uptake ◽  
Protein Corona ◽  
Corona Formation ◽  
Spherical Nucleic Acids ◽  
The Impact

Comparison of Penetratin and Other Homeodomain-Derived Cell-Penetrating Peptides:  Interaction in a Membrane-Mimicking Environment and Cellular Uptake Efficiency†

Biochemistry ◽  
2006 ◽  
Vol 45 (5) ◽  
pp. 1408-1420 ◽  
Author(s):  
Stéphane Balayssac ◽  
Fabienne Burlina ◽  
Odile Convert ◽  
Gérard Bolbach ◽  
Gérard Chassaing ◽  
...  
Keyword(s):  
Cellular Uptake ◽  
Cell Penetrating Peptides ◽  
Uptake Efficiency ◽  
Cell Penetrating ◽  
Cellular Uptake Efficiency

Synthesis of SBA-15 rods with small sizes for enhanced cellular uptake

2014 ◽  
Vol 2 (30) ◽  
pp. 4929-4934 ◽  
Author(s):  
Yannan Yang ◽  
Surajit Karmakar ◽  
Jun Zhang ◽  
Meihua Yu ◽  
Neena Mitter ◽  
...  
Keyword(s):  
Cellular Uptake ◽  
Uptake Efficiency ◽  
Cellular Uptake Efficiency

SBA-15 rods with 80–200 nm in length and 18 ± 8 nm in width have been prepared, showing enhanced cellular uptake efficiency.

The evaluation of cellular uptake efficiency and tumor-targeting ability of MPEG–PDLLA micelles: effect of particle size

RSC Advances ◽  
2016 ◽  
Vol 6 (17) ◽  
pp. 13698-13709 ◽  
Author(s):  
Ying Hao ◽  
YiXing Huang ◽  
YunQi He ◽  
JinRong Peng ◽  
LiJuan Chen ◽  
...  
Keyword(s):  
Particle Size ◽  
Cellular Uptake ◽  
Tumor Targeting ◽  
Particle Sizes ◽  
Uptake Efficiency ◽  
Effect Of Particle Size ◽  
Targeting Ability ◽  
Cellular Uptake Efficiency

The study reported herein describes the cellular uptake efficiency and tumor-targeting ability of MPEG–PDLLA micelles with two different particle sizes.

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