Molecular imprinting polymers and their composites: a promising material for diverse applications

2017 ◽  
Vol 5 (3) ◽  
pp. 388-402 ◽  
Author(s):  
Shabi Abbas Zaidi

Molecular imprinted polymerization is considered one of the most useful preparation strategies to obtain highly selective polymeric materials called molecular imprinted polymers (MIPs).

2013 ◽  
Vol 543 ◽  
pp. 499-502 ◽  
Author(s):  
Florence Lagarde

Molecular imprinting technique allows the preparation of tailor-made materials with high recognition faculty towards target molecules. Molecular imprinted polymers (MIPs) are more robust, easier to manipulate and cheaper than biological receptors, constituting very attractive alternatives to biomolecules as recognition elements in the elaboration of biosensors. In this paper, the principles and advantages of MIP-based impedimetric sensors are described and some examples of application in the biological or environmental fields are given.


Biosensors ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 89
Author(s):  
Shabi Abbas Zaidi

The molecular imprinting polymers (MIPs) have shown their potential in various applications including pharmaceuticals, chemical sensing and biosensing, medical diagnosis, and environmental related issues, owing to their artificial selective biomimetic recognition ability. Despite the challenges posed in the imprinting and recognition of biomacromolecules, the use of MIP for the imprinting of large biomolecular oragnism such as viruses is of huge interest because of the necessity of early diagnosis of virus-induced diseases for clinical and point-of-care (POC) purposes. Thus, many fascinating works have been documented in which such synthetic systems undoubtedly explore a variety of potential implementations, from virus elimination, purification, and diagnosis to virus and bacteria-borne disease therapy. This study is focused comprehensively on the fabrication strategies and their usage in many virus-imprinted works that have appeared in the literature. The drawbacks, challenges, and perspectives are also highlighted.


2020 ◽  
pp. 174751982098037
Author(s):  
Jian-Xiong He ◽  
Huan-Yu Pan ◽  
Li Xu ◽  
Ri-Yuan Tang

Aflatoxins are extremely harmful carcinogens to humans and animals. In recent years, attention has been directed toward the application of molecular imprinting polymers for the separation and detection of aflatoxin. In this review, polymerization methods for the preparation of molecular imprinting polymers for aflatoxin detection, such as lump-bulk polymerization, spherical molecular imprinting polymer synthesis, surface-imprinted polymerization, and electropolymerization, are described. The applications of molecular imprinting polymers in solid-phase extraction, biosensors, and the surface-enhanced Raman detection of aflatoxin are also reviewed in this paper.


2006 ◽  
Vol 53 (11) ◽  
pp. 205-212 ◽  
Author(s):  
M. Le Noir ◽  
B. Guieysse ◽  
B. Mattiasson

This work was conducted to study the potential of molecularly imprinted polymers (MIPs) for the removal of oestradiol at trace concentrations (1 ppm–1 ppb). An MIP synthesised with 17β-oestradiol as template was compared to non-imprinted polymers (NIP) synthesised under the same conditions but without template, a commercial C18 extraction phase and granulated activated carbon. At 1 ppb oestradiol was recovered by 98±2% when using the MIP, compared to 90±1, 79±1, and 84±2% when using the NIP, a C18 phase, or granulated activated carbon, respectively. According to these levels, the MIP was capable of producing an effluent with a quality 5–10 times higher than the other materials. The same levels of oestradiol recovery were achieved with the MIP when supplying 17β-oestradiol at 0.1 ppm. Phenolic compounds added as interferences bound less to the MIP than to the NIP, confirming the selectivity of the MIP. Oestradiol biodegradation was also demonstrated at high concentrations (50 ppm), showing the pollutants can be safely destructed after being enriched by molecular extraction. This study demonstrates the potential of molecular imprinted polymers as a highly efficient specific adsorbent for the removal of trace contaminants.


2012 ◽  
Vol 209 (5) ◽  
pp. 905-910 ◽  
Author(s):  
Jan Alenus ◽  
Pavel Galar ◽  
Anitha Ethirajan ◽  
Frederik Horemans ◽  
Ans Weustenraed ◽  
...  

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