Upconversion NaLuF4 fluorescent nanoprobes for jellyfish cell imaging and irritation assessment of organic dyes

2015 ◽  
Vol 3 (23) ◽  
pp. 6067-6076 ◽  
Author(s):  
Zenghui Chen ◽  
Xiaofeng Wu ◽  
Shigang Hu ◽  
Pan Hu ◽  
Huanyuan Yan ◽  
...  
Keyword(s):  
Cell Imaging ◽  
Organic Molecules ◽  
Organic Dyes ◽  
Good Biocompatibility ◽  
Trace Organic

Upconversion NaLuF4 nanoprobes with intense visible fluorescence and good biocompatibility have been successfully constructed for assessing the irritation of trace organic molecules in jellyfish cells based on the LRET process.

scholarly journals Quick extracellular biosynthesis of low-cadmium ZnxCd1−xS quantum dots with full-visible-region tuneable high fluorescence and its application potential assessment in cell imaging

RSC Advances ◽  
2021 ◽  
Vol 11 (35) ◽  
pp. 21813-21823
Author(s):  
Shiyue Qi ◽  
Ji Chen ◽  
Xianwei Bai ◽  
Yahui Miao ◽  
Shuhui Yang ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Energy Saving ◽  
Metal Nanoparticles ◽  
Cell Imaging ◽  
Visible Region ◽  
Extracellular Biosynthesis ◽  
Application Potential ◽  
Good Biocompatibility ◽  
High Fluorescence ◽  
Environmentally Sound

The biosynthesis of metal nanoparticles/QDs has been universally recognized as environmentally sound and energy-saving, generating less pollution and having good biocompatibility, which is most needed in biological and medical fields.

Recent Advances in the Cancer Bioimaging with Graphene Quantum Dots

2018 ◽  
Vol 25 (25) ◽  
pp. 2876-2893 ◽  
Author(s):  
Keheng Li ◽  
Xinna Zhao ◽  
Gang Wei ◽  
Zhiqiang Su
Keyword(s):  
Quantum Dots ◽  
Biomedical Applications ◽  
Cell Imaging ◽  
Graphene Quantum Dots ◽  
Biological Properties ◽  
Live Cells ◽  
Physical Chemical ◽  
Specific Cancer ◽  
Good Biocompatibility ◽  
Low Cytotoxicity

Fluorescent graphene quantum dots (GQDs) have attracted increasing interest in cancer bioimaging due to their stable photoluminescence (PL), high stability, low cytotoxicity, and good biocompatibility. In this review, we present the synthesis and chemical modification of GQDs firstly, and then introduce their unique physical, chemical, and biological properties like the absorption, PL, and cytotoxicity of GQDs. Finally and most importantly, the recent applications of GQDs in cancer bioimaging are demonstrated in detail, in which we focus on the biofunctionalization of GQDs for specific cancer cell imaging and real-time molecular imaging in live cells. We expect this work would provide valuable guides on the synthesis and modification of GQDs with adjustable properties for various biomedical applications in the future.

scholarly journals Multifunctional NaLnF4@MOF-Ln Nanocomposites with Dual-Mode Luminescence for Drug Delivery and Cell Imaging

Nanomaterials ◽  
2019 ◽  
Vol 9 (9) ◽  
pp. 1274 ◽  
Author(s):  
Wang ◽  
Zhao ◽  
Gao ◽  
Xu ◽  
Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cell Imaging ◽  
Drug Carrier ◽  
Drug Carriers ◽  
Water Soluble ◽  
Dual Mode ◽  
Metal Organic ◽  
Lanthanide Metal ◽  
Good Biocompatibility ◽  
Anti Stokes

Multifunctional nanomaterials for bioprobe and drug carrier have drawn great attention for their applications in the early monitoring the progression and treatment of cancers. In this work, we have developed new multifunctional water-soluble NaLnF4@MOF-Ln nanocomposites with dual-mode luminescence, which is based on stokes luminescent mesoporous lanthanide metal–organic frameworks (MOFs-Y:Eu3+) and anti-stokes luminescent NaYF4:Tm3+/Yb3+ nanoparticles. The fluorescence mechanism and dynamics are investigated and the applications of these nanocomposites as bioprobes and drug carriers in the cancer imaging and treatment are explored. Our results demonstrate that these nanocomposites with the excellent two-color emission show great potential in drug delivery, cancer cell imaging, and treatment, which are attributed to the unique spatial structure and good biocompatibility characteristics of NaLnF4@MOF-Ln nanocomposites.

Novel biocompatible fluorescent polymeric micelles based on 1,8-naphthalimide derivatives for cell imaging

2015 ◽  
Vol 6 (3) ◽  
pp. 364-368 ◽  
Author(s):  
Bei-Yu Liu ◽  
Wan-Xia Wu ◽  
Na Wang ◽  
Xiao-Qi Yu
Keyword(s):  
Self Assembly ◽  
Cell Imaging ◽  
Polymeric Micelles ◽  
Ph Sensor ◽  
Polymeric Micelle ◽  
Living Cells ◽  
Amphiphilic Block Copolymers ◽  
Good Potential ◽  
New Type ◽  
Good Biocompatibility

A new type of fluorescent polymeric micelle was developed by the aqueous self-assembly from amphiphilic block copolymers via click chemistry and showed good potential for application in cell imaging with good biocompatibility. Notably, P1 can readily serve as an excellent intracellular pH sensor in whole living cells based on PET inhibition

Facile synthesis of water-soluble and biocompatible fluorescent nitrogen-doped carbon dots for cell imaging

The Analyst ◽  
2014 ◽  
Vol 139 (7) ◽  
pp. 1692-1696 ◽  
Author(s):  
Weiping Wang ◽  
Ya-Chun Lu ◽  
Hong Huang ◽  
Jiu-Ju Feng ◽  
Jian-Rong Chen ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Cell Imaging ◽  
Water Soluble ◽  
Soluble Nitrogen ◽  
Facile Synthesis ◽  
Nitrogen Doped ◽  
Low Toxicity ◽  
Good Biocompatibility ◽  
Doped Carbon Dots ◽  
Nitrogen Doped Carbon

A simple and green hydrothermal method was developed for preparation of water-soluble nitrogen-doped carbon dots (N-CDs) from streptomycin. The prepared N-CDs reveal low toxicity, high stability and good biocompatibility, which can be used as fluorescent probes for cell imaging.

scholarly journals Ratiometric Polymer Probe for Detection of Peroxynitrite and the Application for Live-Cell Imaging

Molecules ◽  
2019 ◽  
Vol 24 (19) ◽  
pp. 3465
Author(s):  
Hio Kuan Lao ◽  
Jingyun Tan ◽  
Chunfei Wang ◽  
Xuanjun Zhang
Keyword(s):  
Live Cell Imaging ◽  
Cell Imaging ◽  
In Vitro Study ◽  
Water Soluble ◽  
Fluorescence Intensity Ratio ◽  
Oxidation Stress ◽  
Promising Tool ◽  
Good Biocompatibility

Peroxynitrite (ONOO−) is one of the sources of oxidation stress involved in many biological signaling pathways. The role of ONOO− being a double-edged sword in biological systems drives the development of effective detection tools. In this work, a boronate-based polymeric fluorescent probe PB-PVA was synthesized and the probe performance was evaluated. The probe exhibits ratiometric sensing of ONOO− in a range of 0–6 µM. There is good linear relationship between the probe fluorescence intensity ratio and ONOO− concentration. The probe also displays moderate selectivity towards ONOO− over other ROS. Moreover, it is water-soluble and possesses good biocompatibility which aids the imaging of ONOO− in living cells. These properties could make the probe a promising tool in in vitro study related to ONOO−.

scholarly journals The Preparation of Green Fluorescence-Emissioned Carbon Dots/Poly(N-Isopropylacrylamide) Temperature-Sensitive Hydrogels and Research on Their Properties

Polymers ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 1171 ◽  
Author(s):  
Dan Zhao ◽  
Wenting Ma ◽  
Rong Wang ◽  
Xinzhou Yang ◽  
Jun Li ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Fluorescence Spectra ◽  
Cell Imaging ◽  
Fluorescence Probes ◽  
Excitation Wavelength ◽  
Temperature Sensitive ◽  
Green Fluorescence ◽  
Microscope Imaging ◽  
One Step ◽  
Good Biocompatibility

Fluorescence/temperature-sensitive hydrogels, thanks to their properties in fluorescence and temperature sensitivity, have shown a promising outlook in the fields of drug delivery, cell imaging, etc., and thus become the focus of present research. This paper reports the preparation of green-fluorescence/temperature-sensitive hydrogels through one-step radical polymerization with green fluorescence-emissioned carbon dots as fluorescence probes and N-isopropylacrylamide as a monomer. UV-vis spectra, fluorescence spectra, and fluorescence microscope imaging have been used to characterize the prepared hydrogel, and to study their optical and temperature-sensitive properties. It was discovered that the emission of prepared hydrogel is excitation wavelength-dependent, pH responding, and excellent temperature-sensitive, as well as having good biocompatibility. The prepared hydrogel can also be applied as fluorescence ink in the fields of anti-counterfeit identification and appraisal.

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