scholarly journals Quick extracellular biosynthesis of low-cadmium ZnxCd1−xS quantum dots with full-visible-region tuneable high fluorescence and its application potential assessment in cell imaging

RSC Advances ◽  
2021 ◽  
Vol 11 (35) ◽  
pp. 21813-21823
Author(s):  
Shiyue Qi ◽  
Ji Chen ◽  
Xianwei Bai ◽  
Yahui Miao ◽  
Shuhui Yang ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Energy Saving ◽  
Metal Nanoparticles ◽  
Cell Imaging ◽  
Visible Region ◽  
Extracellular Biosynthesis ◽  
Application Potential ◽  
Good Biocompatibility ◽  
High Fluorescence ◽  
Environmentally Sound

The biosynthesis of metal nanoparticles/QDs has been universally recognized as environmentally sound and energy-saving, generating less pollution and having good biocompatibility, which is most needed in biological and medical fields.

Facile and Large-scale Synthesis of Graphene Quantum Dots Functionalized with Morpholine for Selective Targeting and Imaging of Lysosome

NANO ◽  
2021 ◽  
pp. 2150113
Author(s):  
Yingying Nie ◽  
Zengjie Fan
Keyword(s):  
Quantum Dots ◽  
Large Scale ◽  
Graphene Quantum Dots ◽  
Diagnosis And Treatment ◽  
Uniform Size ◽  
Scale Method ◽  
Selective Targeting ◽  
Application Potential ◽  
Good Biocompatibility ◽  
Imaging Properties

The lack of targeting selection to lysosome limits the application of graphene quantum dots (GQDs) in the diagnosis and treatment of lysosome-related disease. In this study, we developed a facile, environmentally friendly and large-scale method to prepare [Formula: see text]-aminomorpholine (Am)-modified GQDs (Am-GQDs) via a simple hydrothermal method. The physicochemical, optical, biocompatible and targeted imaging properties were evaluated systematically. The results indicated that the synthesized Am-GQDs had a uniform size distribution and the size was around 2[Formula: see text]nm. In addition, the synthesized Am-GQDs had excellent optical properties, fluorescent stability, and good biocompatibility. More importantly, they can selectively target and image lysosome in a relatively short coculture time with cells, demonstrating their application potential in the diagnosis and treatment of lysosomal-related diseases.

Recent Advances in the Cancer Bioimaging with Graphene Quantum Dots

2018 ◽  
Vol 25 (25) ◽  
pp. 2876-2893 ◽  
Author(s):  
Keheng Li ◽  
Xinna Zhao ◽  
Gang Wei ◽  
Zhiqiang Su
Keyword(s):  
Quantum Dots ◽  
Biomedical Applications ◽  
Cell Imaging ◽  
Graphene Quantum Dots ◽  
Biological Properties ◽  
Live Cells ◽  
Physical Chemical ◽  
Specific Cancer ◽  
Good Biocompatibility ◽  
Low Cytotoxicity

Fluorescent graphene quantum dots (GQDs) have attracted increasing interest in cancer bioimaging due to their stable photoluminescence (PL), high stability, low cytotoxicity, and good biocompatibility. In this review, we present the synthesis and chemical modification of GQDs firstly, and then introduce their unique physical, chemical, and biological properties like the absorption, PL, and cytotoxicity of GQDs. Finally and most importantly, the recent applications of GQDs in cancer bioimaging are demonstrated in detail, in which we focus on the biofunctionalization of GQDs for specific cancer cell imaging and real-time molecular imaging in live cells. We expect this work would provide valuable guides on the synthesis and modification of GQDs with adjustable properties for various biomedical applications in the future.

scholarly journals CdTe Quantum dots Modified by Polyamidoamine Dendrimers for Cell Imaging

2012 ◽  
Vol 9 (1) ◽  
pp. 171-174 ◽  
Author(s):  
Jun'An Liu ◽  
Xiaolei Wei ◽  
Jianhua Cao ◽  
Hong Jiang
Keyword(s):  
Quantum Dots ◽  
Cell Imaging ◽  
Water Soluble ◽  
Cdte Quantum Dots ◽  
In Vitro Toxicity ◽  
Covalent Bonds ◽  
Polyamidoamine Dendrimers ◽  
A Cell ◽  
Good Biocompatibility

Water soluble CdTe quantum dots have shown potential as a platform for development of live cell imaging, but their cytotoxicity limits their biological applications. To decrease their cytotoxicity, an approach to modify CdTe quantum dots (QDs) with polyamidoamine (PAMAM) was employed by forming covalent bonds between them. The resultant nanocomposites as a cell imaging bioprobe for live PK15 and their in vitro toxicity were also investigated. The results showed that the prepared nanocomposites were able to enter PK15 cells with good biocompatibility and low cellular toxicity.

The Preparation of Water-Solution Mn-Doped ZnS Quantum Dots

2012 ◽  
Vol 601 ◽  
pp. 3-6
Author(s):  
Se Shi ◽  
Ji Mei Zhang ◽  
Zhao Dai
Keyword(s):  
Quantum Dots ◽  
Storage Time ◽  
Cell Imaging ◽  
Water Solution ◽  
Absorption Spectrometry ◽  
Infrared Spectrometry ◽  
Visible Absorption ◽  
Pl Emission ◽  
High Fluorescence ◽  
Mn Doped

High-Fluorescence Mn-doped ZnS quantum dots ( QDs) capped with L-Cysteine (L-Cys) were prepared in the aqueous were presented in this paper. The influences of the pH, the doped-quantity of Mn2+ and the storage time on the PL emission of quantum dots were studied. The samples were characterized by means of ultraviolet-visible absorption spectrometry (UV-vis), photoluminescence (PL) emission and infrared spectrometry (FTIR). The results showed that the fluorescence intensity reached the maximum when the pH was 10, the doped-quantity of Mn2+ was 3% and the storage time was about 7 days. The solubility of the quantum dots in the water was excellent. Because of these advantages, it can be used in biological fields, such as biomarkers, cell imaging, and sensor and so on.

Trends in Nanotechnology for in vivo Cancer Diagnosis: Products and Patents

2020 ◽  
Vol 26 (18) ◽  
pp. 2167-2181
Author(s):  
Tatielle do Nascimento ◽  
Melanie Tavares ◽  
Mariana S.S.B. Monteiro ◽  
Ralph Santos-Oliveira ◽  
Adriane R. Todeschini ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Quantum Dots ◽  
Magnetic Resonance ◽  
Metal Nanoparticles ◽  
Cancer Diagnosis ◽  
Imaging Techniques ◽  
Tumor Detection ◽  
Abnormal Growth ◽  
Pharmaceutical Nanotechnology

Background: Cancer is a set of diseases formed by abnormal growth of cells leading to the formation of the tumor. The diagnosis can be made through symptoms’ evaluation or imaging tests, however, the techniques are limited and the tumor detection may be late. Thus, pharmaceutical nanotechnology has emerged to optimize the cancer diagnosis through nanostructured contrast agent’s development. Objective: This review aims to identify commercialized nanomedicines and patents for cancer diagnosis. Methods: The databases used for scientific articles research were Pubmed, Science Direct, Scielo and Lilacs. Research on companies’ websites and articles for the recognition of commercial nanomedicines was performed. The Derwent tool was applied for patent research. Results: This article aimed to research on nanosystems based on nanoparticles, dendrimers, liposomes, composites and quantum dots, associated to imaging techniques. Commercialized products based on metal and composite nanoparticles, associated with magnetic resonance and computed tomography, have been observed. The research conducted through Derwent tool displayed a small number of patents using nanotechnology for cancer diagnosis. Among these patents, the most significant number was related to the use of systems based on metal nanoparticles, composites and quantum dots. Conclusion: Although few systems are found in the market and patented, nanotechnology appears as a promising field for the development of new nanosystems in order to optimize and accelerate the cancer diagnosis.

Applications of novel quantum dots derived from layered materials in Cancer cell imaging

FlatChem ◽  
2021 ◽  
pp. 100246
Author(s):  
Salar Khaledian ◽  
Farhad Nalaini ◽  
Mahmood Mehrbakhsh ◽  
Mohadese Abdoli ◽  
Saleh Salehi Zahabi
Keyword(s):  
Quantum Dots ◽  
Cancer Cell ◽  
Cell Imaging ◽  
Layered Materials ◽  
Cancer Cell Imaging

Aqueous synthesis of CuInZnS/ZnS quantum dots by using dual stabilizers: A targeting nanoprobe for cell imaging

2016 ◽  
Vol 173 ◽  
pp. 242-247 ◽  
Author(s):  
Jayaraman Vinayagam ◽  
Guan-Rong Chen ◽  
Ting-Yi Huang ◽  
Jinn-Hsuan Ho ◽  
Yong-Chien Ling ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Cell Imaging ◽  
Aqueous Synthesis
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