Hybrid polymeric nano-capsules loaded with gold nanoclusters and indocyanine green for dual-modal imaging and photothermal therapy

2016 ◽  
Vol 4 (5) ◽  
pp. 910-919 ◽  
Author(s):  
Wei Gu ◽  
Qi Zhang ◽  
Ting Zhang ◽  
Yingying Li ◽  
Jian Xiang ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Photothermal Therapy ◽  
Gold Nanoclusters ◽  
Theranostic Applications

BSA-capped gold nanoclusters (AuNCs) and indocyanine green (ICG) loaded polymeric nano-capsules for theranostic applications.

Indocyanine Green–Coated Gold Nanoclusters for Photoacoustic Imaging and Photothermal Therapy

2019 ◽  
Vol 2 (9) ◽  
pp. 1900088 ◽  
Author(s):  
Elizabeth Higbee‐Dempsey ◽  
Ahmad Amirshaghaghi ◽  
Matthew J. Case ◽  
Joann Miller ◽  
Theresa M. Busch ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Gold Nanoclusters

scholarly journals Organic dots (O-dots) for theranostic applications: preparation and surface engineering

RSC Advances ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 2253-2291
Author(s):  
Amin Shiralizadeh Dezfuli ◽  
Elmira Kohan ◽  
Sepand Tehrani Fateh ◽  
Neda Alimirzaei ◽  
Hamidreza Arzaghi ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Photodynamic Therapy ◽  
Photothermal Therapy ◽  
Biomedical Applications ◽  
Surface Engineering ◽  
Graphene Quantum Dots ◽  
Carbon Quantum Dots ◽  
Cargo Delivery ◽  
Bio Imaging ◽  
Theranostic Applications

Organic dots is a term used to represent materials including graphene quantum dots and carbon quantum dots because they rely on the presence of other atoms (O, H, and N) for their photoluminescence or fluorescence properties. Cargo delivery, bio-imaging, photodynamic therapy and photothermal therapy are major biomedical applications of organic dots.

scholarly journals Exploiting cyanine dye J-aggregates/monomer equilibrium in hydrophobic protein pockets for efficient multi-step phototherapy: An innovative concept for smart nanotheranostics

Nanoscale ◽  
2021 ◽  
Author(s):  
Matias Luis Picchio ◽  
Julian Bergueiro Álvarez ◽  
Stefanie Wedepohl ◽  
Roque J Minari ◽  
Cecilia Ines Alvarez Igarzabal ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Contrast Agent ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Cyanine Dye ◽  
Hydrophobic Protein ◽  
Nir Dyes ◽  
Protein Pockets ◽  
J Aggregates ◽  
Innovative Concept

After several decades of development in the field of near-infrared (NIR) dyes for photothermal therapy (PTT), indocyanine green (ICG) still remains the only FDA-approved NIR contrast agent. However, upon NIR...

scholarly journals Gold Nanorods for Light-Based Lung Cancer Theranostics

2018 ◽  
Vol 19 (11) ◽  
pp. 3318 ◽  
Author(s):  
Oscar Knights ◽  
James McLaughlan
Keyword(s):  
Gold Nanorods ◽  
Photothermal Therapy ◽  
Continuous Wave ◽  
Low Cost ◽  
Laser System ◽  
Controlled Synthesis ◽  
Surface Plasmon Resonances ◽  
Plasmon Resonances ◽  
Theranostic Applications ◽  
Cancer Theranostics

Gold nanorods (AuNRs) have the potential to be used in photoacoustic (PA) imaging and plasmonic photothermal therapy (PPTT) due to their unique optical properties, biocompatibility, controlled synthesis, and tuneable surface plasmon resonances (SPRs). Conventionally, continuous-wave (CW) lasers are used in PPTT partly due to their small size and low cost. However, if pulsed-wave (PW) lasers could be used to destroy tissue then combined theranostic applications, such as PA-guided PPTT, would be possible using the same laser system and AuNRs. In this study, we present the effects of AuNR size on PA response, PW-PPTT efficacy, and PA imaging in a tissue-mimicking phantom, as a necessary step in the development of AuNRs towards clinical use. At equivalent NP/mL, the PA signal intensity scaled with AuNR size, indicating that overall mass has an effect on PA response, and reinforcing the importance of efficient tumour targeting. Under PW illumination, all AuNRs showed toxicity at a laser fluence below the maximum permissible exposure to skin, with a maximum of 80% cell-death exhibited by the smallest AuNRs, strengthening the feasibility of PW-PPTT. The theranostic potential of PW lasers combined with AuNRs has been demonstrated for application in the lung.

scholarly journals Indocyanine Green Nanoparticles for Theranostic Applications

2013 ◽  
Vol 5 (3) ◽  
pp. 145-150 ◽  
Author(s):  
Zonghai Sheng ◽  
Dehong Hu ◽  
Miaomiao Xue ◽  
Meng He ◽  
Ping Gong ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Theranostic Applications

Bubble-generating polymersomes loaded with both indocyanine green and doxorubicin for effective chemotherapy combined with photothermal therapy

2018 ◽  
Vol 75 ◽  
pp. 386-397 ◽  
Author(s):  
Dunwan Zhu ◽  
Fan Fan ◽  
Chenlu Huang ◽  
Zhiming Zhang ◽  
Yu Qin ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Photothermal Therapy

scholarly journals Cancer Photothermal Therapy with ICG-Conjugated Gold Nanoclusters

2020 ◽  
Vol 31 (5) ◽  
pp. 1522-1528 ◽  
Author(s):  
Xingya Jiang ◽  
Bujie Du ◽  
Yingyu Huang ◽  
Mengxiao Yu ◽  
Jie Zheng
Keyword(s):  
Photothermal Therapy ◽  
Gold Nanoclusters

Concurrent photothermal therapy and photodynamic therapy for cutaneous squamous cell carcinoma by gold nanoclusters under a single NIR laser irradiation

2019 ◽  
Vol 7 (44) ◽  
pp. 6924-6933 ◽  
Author(s):  
Pei Liu ◽  
Weitao Yang ◽  
Lei Shi ◽  
Haiyan Zhang ◽  
Yan Xu ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Photodynamic Therapy ◽  
Cell Carcinoma ◽  
Laser Irradiation ◽  
Squamous Cell ◽  
Photothermal Therapy ◽  
Gold Nanoclusters ◽  
Cutaneous Squamous Cell Carcinoma ◽  
Single Drug ◽  
Nir Laser

The concurrent photothermal and photodynamic therapy of cutaneous squamous cell carcinoma by a single drug of Au25(Capt)18 nanoclusters is demonstrated, together with a preliminary immune response study conducted under a single NIR laser irradiation.

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