Nanoporous molybdenum carbide nanowires: a novel sensing platform for DNA detection

2015 ◽  
Vol 3 (36) ◽  
pp. 7173-7176 ◽  
Author(s):  
Zhicai Xing ◽  
Lei Wang ◽  
Xuping Sun ◽  
Yuquan He ◽  
Abdullah M. Asiri
Keyword(s):  
Nucleic Acid ◽  
Molybdenum Carbide ◽  
Dna Detection ◽  
Nucleic Acid Detection ◽  
Sensing Platform ◽  
First Time

Nanoporous Mo2C nanowires have been successfully demonstrated as an effective sensing platform for nucleic acid detection for the first time.

Cobalt disulfide nanowires as an effective fluorescent sensing platform for DNA detection

2016 ◽  
Vol 4 (17) ◽  
pp. 2860-2863 ◽  
Author(s):  
Zhicai Xing ◽  
Lei Wang ◽  
Xiurong Yang
Keyword(s):  
Nucleic Acid ◽  
Hydrothermal Method ◽  
Dna Detection ◽  
Nucleic Acid Detection ◽  
Fluorescent Sensing ◽  
Sensing Platform ◽  
Cobalt Disulfide ◽  
First Time

Cobalt disulfide nanowires are synthesized in solution using a facile two-step hydrothermal method for the first time and applied as an effective sensing platform for nucleic acid detection.

Black phosphorus nanoparticles as a novel fluorescent sensing platform for nucleic acid detection

2017 ◽  
Vol 1 (6) ◽  
pp. 1130-1136 ◽  
Author(s):  
Ying Teng Yew ◽  
Zdeněk Sofer ◽  
Carmen C. Mayorga-Martinez ◽  
Martin Pumera
Keyword(s):  
Nucleic Acid ◽  
Dna Detection ◽  
Black Phosphorus ◽  
Nucleic Acid Detection ◽  
Fluorescent Sensing ◽  
Sensing Platform

Black phosphorus nanoparticles were successfully employed as nanofluorophores in the development of a fluorescent sensing platform for DNA detection.

Coordination Polymer Nanobelts as an Effective Sensing Platform for Fluorescence-enhanced Nucleic Acid Detection

2011 ◽  
Vol 32 (12) ◽  
pp. 899-904 ◽  
Author(s):  
Hailong Li ◽  
Lei Wang ◽  
Junfeng Zhai ◽  
Yingwei Zhang ◽  
Jingqi Tian ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Coordination Polymer ◽  
Nucleic Acid Detection ◽  
Sensing Platform

Nucleic acid detection using single-walled carbon nanohorns as a fluorescent sensing platform

2011 ◽  
Vol 47 (21) ◽  
pp. 6099 ◽  
Author(s):  
Shuyun Zhu ◽  
Zhongyuan Liu ◽  
Wei Zhang ◽  
Shuang Han ◽  
Lianzhe Hu ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acid Detection ◽  
Carbon Nanohorns ◽  
Single Walled Carbon ◽  
Fluorescent Sensing ◽  
Sensing Platform

scholarly journals CRISPR-Assisted DNA Detection, a novel dCas9-based DNA detection technique

2020 ◽  
Author(s):  
Xinhui Xu ◽  
Tao Luo ◽  
Jinliang Gao ◽  
Na Lin ◽  
Weiwei Li ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Room Temperature ◽  
Dna Detection ◽  
Point Of Care ◽  
Hpv Infection ◽  
Solid Support ◽  
Human Papillomaviruses ◽  
Nucleic Acid Detection ◽  
Detection Techniques ◽  
Signal Readout

AbstractNucleic acid detection techniques are always critical to diagnosis, especially in the background of the present COVID-19 pandemic. The simple and rapid detection techniques with high sensitivity and specificity are always urgently needed. However, the current nucleic acid detection techniques are still limited the traditional amplification and hybridization. To overcome the limitation, we here develop a CRISPR/Cas9-assisted DNA detection (CADD). In this detection, DNA sample is incubated with a pair of capture sgRNAs (sgRNAa and sgRNAb) specific to a target DNA, dCas9, a signal readout-related probe, and an oligo-coated solid support beads or microplate at room temperature for 15 min. During this incubation, the dCas9-sgRNA-DNA complex is formed and captured on solid support by the capture sequence of sgRNAa and the signal readout-related probe is captured by the capture sequence of sgRNAb. Finally the detection result is reported by a fluorescent or colorimetric signal readout. This detection was verified by detecting DNA of bacteria, cancer cell and virus. Especially, by designing a set of sgRNAs specific to 15 high-risk human papillomaviruses (HPVs), the HPV infection in 64 clinical cervical samples were successfully detected by the method. All detections can be finished in 30 minutes at room temperature. This detection holds promise for rapid on-the-spot detection or point-of-care testing (POCT).

scholarly journals A handheld magnetic sensing platform for antigen and nucleic acid detection

The Analyst ◽  
2014 ◽  
Vol 139 (6) ◽  
pp. 1403-1411 ◽  
Author(s):  
Alex Pai ◽  
Aroutin Khachaturian ◽  
Stephen Chapman ◽  
Alexander Hu ◽  
Hua Wang ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acid Detection ◽  
Magnetic Sensing ◽  
Sensing Platform

A portable magnetic-based biosensing platform is introduced for antigen and nucleic acid detection utilizing the “magnetic freezing” technique.

β-Ni(OH)2 nanosheets: an effective sensing platform for constructing nucleic acid-based optical sensors

2017 ◽  
Vol 5 (35) ◽  
pp. 7426-7432 ◽  
Author(s):  
Hui Zhou ◽  
Junbin Peng ◽  
Xinlan Qiu ◽  
Yansha Gao ◽  
Limin Lu ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Optical Sensors ◽  
Short Oligonucleotide ◽  
Sensing Platform ◽  
First Time ◽  
Differential Affinity

We report for the first time that β-Ni(OH)2 nanosheets can exhibit differential affinity toward short oligonucleotide fragment versus ssDNA probe and the absorbed DNA can also be desorbed by degrading the β-Ni(OH)2 nanosheets.

Tetracyanoquinodimethane nanoparticles as an effective sensing platform for fluorescent nucleic acid detection

2011 ◽  
Vol 3 (5) ◽  
pp. 1051 ◽  
Author(s):  
Hailong Li ◽  
Lei Wang ◽  
Junfeng Zhai ◽  
Yonglan Luo ◽  
Yingwei Zhang ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acid Detection ◽  
Sensing Platform
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