Multi-walled carbon nanotubes as an effective fluorescent sensing platform for nucleic acid detection

2011 ◽  
Vol 21 (3) ◽  
pp. 824-828 ◽  
Author(s):  
Hailong Li ◽  
Jingqi Tian ◽  
Lei Wang ◽  
Yingwei Zhang ◽  
Xuping Sun
Keyword(s):  
Carbon Nanotubes ◽  
Nucleic Acid ◽  
Nucleic Acid Detection ◽  
Fluorescent Sensing ◽  
Sensing Platform ◽  
Multi Walled Carbon Nanotubes ◽  
Walled Carbon Nanotubes

Selective Sensing Platform Utilizing Graphitized Multi-Walled Carbon Nanotubes for Monitoring of Ondansetron and Paracetamol

2020 ◽  
Vol 16 ◽  
Author(s):  
Biljana Nigović ◽  
Iva Šimunić ◽  
Ana Mornar
Keyword(s):  
Carbon Nanotubes ◽  
Cation Exchange ◽  
Supporting Electrolyte ◽  
Polymer Concentration ◽  
Fixed Dose ◽  
Sensing Platform ◽  
Multi Walled Carbon Nanotubes ◽  
Electroanalytical Method ◽  
Walled Carbon Nanotubes

Background: Ondansetron and paracetamol are often co-administrated to prevent and treat nausea and vomiting caused by anaesthesia and to control of postoperative pain. In addition, ondansetron is used as the first-line antiemetic in paracetamol overdose. Therefore, selective and sensitive method for their simultaneous analysis is of a great importance. The electroanalytical methods are highly sensitive and offer many possibilities for new sensor platform design. However, at present, no electroanalytical method for simultaneous determination of these drugs has been proposed. Objective: The aim of this study was to develop a novel nanosensor for selective monitoring of ondansetron and paracetamol in pharmaceutical and biological samples without expensive and time-consuming pretreatments. Methods: The graphitized multi-walled carbon nanotubes embedded in a cation exchange polymer matrix was selected, among various surface functionalizations evaluated, to design novel sensor. Based on its excellent sensing performance, the first electroanalytical method was developed for rapid concurrent determination of investigated drugs. Results: The scanning electron microscopy study showed interlinked nanoporous network structure and highly enlarged active surface. The developed sensor facilitated electron transfer in the oxidation of both drugs and tremendously enhanced the adsorption capacity for ondasetron, thus exhibiting significant increase of drug responses and sensitivity. To obtain much sensitive response of investigated drugs the effect of pH values of supporting electrolyte, dispersed nanomaterial amount, the cation exchange polymer concentration, drop-casting volume of nanocomposite suspension, accumulation potential and deposition time on the peak current was evaluated. The developed electroanalytical method was validated and practical utility of the proposed nanosensor was tested. Conclusion: The developed sensor is promising sensing platform with a fast response time for analysis of ondansetron and paracetamol at very different concentration levels found in their fixed-dose combination and human serum sample after recommended daily doses showing its potential usage in pharmaceutical quality control and clinical research.

Mesoporous Pd@Pt core–shell nanoparticles supported on multi-walled carbon nanotubes as a sensing platform: application in simultaneous electrochemical detection of anticancer drugs doxorubicin and dasatinib

2019 ◽  
Vol 11 (4) ◽  
pp. 443-453 ◽  
Author(s):  
Pramod K. Kalambate ◽  
Yankai Li ◽  
Yue Shen ◽  
Yunhui Huang
Keyword(s):  
Carbon Nanotubes ◽  
Anticancer Drugs ◽  
Electrochemical Detection ◽  
Simultaneous Detection ◽  
Core Shell ◽  
Shell Nanoparticles ◽  
Sensing Platform ◽  
Multi Walled Carbon Nanotubes ◽  
Core Shell Nanoparticles ◽  
Walled Carbon Nanotubes

A novel electrochemical sensor based on Pd@Pt/MWCNT composite for simultaneous detection of doxorubicin and dasatinib.

Cobalt disulfide nanowires as an effective fluorescent sensing platform for DNA detection

2016 ◽  
Vol 4 (17) ◽  
pp. 2860-2863 ◽  
Author(s):  
Zhicai Xing ◽  
Lei Wang ◽  
Xiurong Yang
Keyword(s):  
Nucleic Acid ◽  
Hydrothermal Method ◽  
Dna Detection ◽  
Nucleic Acid Detection ◽  
Fluorescent Sensing ◽  
Sensing Platform ◽  
Cobalt Disulfide ◽  
First Time

Cobalt disulfide nanowires are synthesized in solution using a facile two-step hydrothermal method for the first time and applied as an effective sensing platform for nucleic acid detection.

Nucleic acid detection using single-walled carbon nanohorns as a fluorescent sensing platform

2011 ◽  
Vol 47 (21) ◽  
pp. 6099 ◽  
Author(s):  
Shuyun Zhu ◽  
Zhongyuan Liu ◽  
Wei Zhang ◽  
Shuang Han ◽  
Lianzhe Hu ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acid Detection ◽  
Carbon Nanohorns ◽  
Single Walled Carbon ◽  
Fluorescent Sensing ◽  
Sensing Platform

Novel electrochemical sensing platform based on a molecularly imprinted polymer-decorated 3D-multi-walled carbon nanotube intercalated graphene aerogel for selective and sensitive detection of dopamine

2020 ◽  
Vol 12 (14) ◽  
pp. 1845-1851 ◽  
Author(s):  
Xue Ma ◽  
Feng Gao ◽  
Runying Dai ◽  
Guangbin Liu ◽  
Ying Zhang ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Molecularly Imprinted Polymer ◽  
Electrochemical Sensing ◽  
Imprinted Polymer ◽  
Graphene Aerogel ◽  
Molecularly Imprinted ◽  
Sensing Platform ◽  
Multi Walled Carbon Nanotube ◽  
Multi Walled Carbon Nanotubes ◽  
Walled Carbon Nanotubes

A novel molecularly imprinted electrochemical sensor for detection of dopamine (DA) has been fabricated with multi-walled carbon nanotubes spaced graphene aerogels (MWCNTs/GAs) as sensing substrate and polypyrrole (PPy) as molecularly imprinted polymer (MIP).

scholarly journals Conjugation polymer nanobelts: a novel fluorescent sensing platform for nucleic acid detection †

2010 ◽  
Vol 39 (6) ◽  
pp. e37-e37 ◽  
Author(s):  
Lei Wang ◽  
Yingwei Zhang ◽  
Jingqi Tian ◽  
Hailong Li ◽  
Xuping Sun
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acid Detection ◽  
Fluorescent Sensing ◽  
Sensing Platform

Black phosphorus nanoparticles as a novel fluorescent sensing platform for nucleic acid detection

2017 ◽  
Vol 1 (6) ◽  
pp. 1130-1136 ◽  
Author(s):  
Ying Teng Yew ◽  
Zdeněk Sofer ◽  
Carmen C. Mayorga-Martinez ◽  
Martin Pumera
Keyword(s):  
Nucleic Acid ◽  
Dna Detection ◽  
Black Phosphorus ◽  
Nucleic Acid Detection ◽  
Fluorescent Sensing ◽  
Sensing Platform

Black phosphorus nanoparticles were successfully employed as nanofluorophores in the development of a fluorescent sensing platform for DNA detection.

CdS quantum dots as a fluorescent sensing platform for nucleic acid detection

2011 ◽  
Vol 175 (3-4) ◽  
pp. 355-359 ◽  
Author(s):  
Wenbo Lu ◽  
Xiaoyun Qin ◽  
Yonglan Luo ◽  
Guohui Chang ◽  
Xuping Sun
Keyword(s):  
Quantum Dots ◽  
Nucleic Acid ◽  
Nucleic Acid Detection ◽  
Cds Quantum Dots ◽  
Fluorescent Sensing ◽  
Sensing Platform
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