scholarly journals Insulating and semiconducting polymeric free-standing nanomembranes with biomedical applications

2015 ◽  
Vol 3 (29) ◽  
pp. 5904-5932 ◽  
Author(s):  
Maria M. Pérez-Madrigal ◽  
Elaine Armelin ◽  
Jordi Puiggalí ◽  
Carlos Alemán

Free-standing nanomembranes, which are emerging as versatile elements in biomedical applications, are evolving from being composed of insulating (bio)polymers to electroactive conducting polymers.

2016 ◽  
Vol 13 (12) ◽  
pp. 1224-1229 ◽  
Author(s):  
Daniela Pignatelli ◽  
Eloisa Sardella ◽  
Fabio Palumbo ◽  
Chiara Lo Porto ◽  
Silvia Taccola ◽  
...  

2019 ◽  
pp. 783-812
Author(s):  
Alexander R. Harris ◽  
Paul J. Molino ◽  
Caiyun Wang ◽  
Gordon G. Wallace ◽  
Zhilian Yue

2020 ◽  
Vol 11 (4) ◽  
pp. 71 ◽  
Author(s):  
John H. T. Luong ◽  
Tarun Narayan ◽  
Shipra Solanki ◽  
Bansi D. Malhotra

Conducting polymers (CPs) have been at the center of research owing to their metal-like electrochemical properties and polymer-like dispersion nature. CPs and their composites serve as ideal functional materials for diversified biomedical applications like drug delivery, tissue engineering, and diagnostics. There have also been numerous biosensing platforms based on polyaniline (PANI), polypyrrole (PPY), polythiophene (PTP), and their composites. Based on their unique properties and extensive use in biosensing matrices, updated information on novel CPs and their role is appealing. This review focuses on the properties and performance of biosensing matrices based on CPs reported in the last three years. The salient features of CPs like PANI, PPY, PTP, and their composites with nanoparticles, carbon materials, etc. are outlined along with respective examples. A description of mediator conjugated biosensor designs and enzymeless CPs based glucose sensing has also been included. The future research trends with required improvements to improve the analytical performance of CP-biosensing devices have also been addressed.


2013 ◽  
Vol 810 ◽  
pp. 173-216 ◽  
Author(s):  
Amir Al-Ahmed ◽  
Haitham M. Bahaidarah ◽  
Mohammad A. Jafar Mazumder

Electrically conducting polymers (ECPs) are finding applications in various fields of science owing to their fascinating characteristic properties such as binding molecules, tuning their properties, direct communication to produce a range of analytical signals and new analytical applications. Polyaniline (PANI) is one such ECP that has been extensively used and investigated over the last decade for direct electron transfer leading towards fabrication of mediator-less biosensors. In this review article, significant attention has been paid to the various polymerization techniques of polyaniline as a transducer material, and their use in enzymes/biomolecules immobilization methods to study their bio-catalytic properties as a biosensor for potential biomedical applications.


Author(s):  
Alexander N. Zelikin ◽  
David M. Lynn ◽  
Jian Farhadi ◽  
Ivan Martin ◽  
Venkatram Shastri ◽  
...  

2004 ◽  
Vol 4 (2-4) ◽  
pp. 347-350 ◽  
Author(s):  
Marija Gizdavic-Nikolaidis ◽  
Jadranka Travas-Sejdic ◽  
Graham A. Bowmaker ◽  
Ralph P. Cooney ◽  
Corrina Thompson ◽  
...  

2016 ◽  
Vol 6 (6) ◽  
pp. 20160052 ◽  
Author(s):  
Gabriele Barrera ◽  
Loredana Serpe ◽  
Federica Celegato ◽  
Marco Coїsson ◽  
Katia Martina ◽  
...  

A nanofabrication technique based on self-assembling of polystyrene nanospheres is used to obtain magnetic Ni 80 Fe 20 nanoparticles with a disc shape. The free-standing nanodiscs (NDs) have diameter and thickness of about 630 nm and 30 nm, respectively. The versatility of fabrication technique allows one to cover the ND surface with a protective gold layer with a thickness of about 5 nm. Magnetization reversal has been studied by room-temperature hysteresis loop measurements in water-dispersed free-standing NDs. The reversal shows zero remanence, high susceptibility and nucleation/annihilation fields due to spin vortex formation. In order to investigate their potential use in biomedical applications, the effect of NDs coated with or without the protective gold layer on cell growth has been evaluated. A successful attempt to bind cysteine-fluorescein isothiocyanate (FITC) derivative to the gold surface of magnetic NDs has been exploited to verify the intracellular uptake of the NDs by cytofluorimetric analysis using the FITC conjugate.


2016 ◽  
Vol 858 ◽  
pp. 1010-1014 ◽  
Author(s):  
Stephen E. Saddow ◽  
Christopher L. Frewin ◽  
Fabiola Araujo Cespedes ◽  
Marioa Gazziro ◽  
Evans Bernadin ◽  
...  

Silicon carbide is a well-known wide-band gap semiconductor traditionally used in power electronics and solid-state lighting due to its extremely low intrinsic carrier concentration and high thermal conductivity. What is only recently being discovered is that it possesses excellent compatibility within the biological world. Since publication of the first edition of Silicon Carbide Biotechnology: A Biocompatible Semiconductor for Advanced Biomedical Devices and Applications five years ago [1], significant progress has been made on numerous research and development fronts. In this paper three very promising developments are briefly highlighted – progress towards the realization of a continuous glucose monitoring system, implantable neural interfaces made from free-standing 3C-SiC, and a custom-made low-power ‘wireless capable’ four channel neural recording chip for brain-machine interface applications.


2015 ◽  
Vol 6 (1) ◽  
Author(s):  
Shaohua Liu ◽  
Pavlo Gordiichuk ◽  
Zhong-Shuai Wu ◽  
Zhaoyang Liu ◽  
Wei Wei ◽  
...  

2021 ◽  
Vol 8 (3) ◽  
pp. 38
Author(s):  
Aver Hemben ◽  
Iva Chianella ◽  
Glenn John Thomas Leighton

Despite the lifesaving medical discoveries of the last century, there is still an urgent need to improve the curative rate and reduce mortality in many fatal diseases such as cancer. One of the main requirements is to find new ways to deliver therapeutics/drugs more efficiently and only to affected tissues/organs. An exciting new technology is nanomaterials which are being widely investigated as potential nanocarriers to achieve localized drug delivery that would improve therapy and reduce adverse drug side effects. Among all the nanocarriers, iron oxide nanoparticles (IONPs) are one of the most promising as, thanks to their paramagnetic/superparamagnetic properties, they can be easily modified with chemical and biological functions and can be visualized inside the body by magnetic resonance imaging (MRI), while delivering the targeted therapy. Therefore, iron oxide nanoparticles were produced here with a novel method and their properties for potential applications in both diagnostics and therapeutics were investigated. The novel method involves production of free standing IONPs by inert gas condensation via the Mantis NanoGen Trio physical vapor deposition system. The IONPs were first sputtered and deposited on plasma cleaned, polyethylene glycol (PEG) coated silicon wafers. Surface modification of the cleaned wafer with PEG enabled deposition of free-standing IONPs, as once produced, the soft-landed IONPs were suspended by dissolution of the PEG layer in water. Transmission electron microscopic (TEM) characterization revealed free standing, iron oxide nanoparticles with size < 20 nm within a polymer matrix. The nanoparticles were analyzed also by Atomic Force Microscope (AFM), Dynamic Light Scattering (DLS) and NanoSight Nanoparticle Tacking Analysis (NTA). Therefore, our work confirms that inert gas condensation by the Mantis NanoGen Trio physical vapor deposition sputtering at room temperature can be successfully used as a scalable, reproducible process to prepare free-standing IONPs. The PEG- IONPs produced in this work do not require further purification and thanks to their tunable narrow size distribution have potential to be a powerful tool for biomedical applications.


Sign in / Sign up

Export Citation Format

Share Document