scholarly journals Strong Brønsted acid promoted asymmetric hydrogenation of isoquinolines and quinolines catalyzed by a Rh–thiourea chiral phosphine complex via anion binding

2016 ◽  
Vol 7 (5) ◽  
pp. 3047-3051 ◽  
Author(s):  
Jialin Wen ◽  
Renchang Tan ◽  
Shaodong Liu ◽  
Qingyang Zhao ◽  
Xumu Zhang

Catalyzed by a Rh/bisphosphine–thiourea (L1) complex, isoquinolines and quinolines are hydrogenated with high conversions and high enantioselectivities.

2018 ◽  
Vol 20 (14) ◽  
pp. 4390-4390
Author(s):  
Jialin Wen ◽  
Xiangru Fan ◽  
Renchang Tan ◽  
Hui-Chun Chien ◽  
Qinghai Zhou ◽  
...  

2018 ◽  
Vol 20 (8) ◽  
pp. 2143-2147 ◽  
Author(s):  
Jialin Wen ◽  
Xiangru Fan ◽  
Renchang Tan ◽  
Hui-Chun Chien ◽  
Qinghai Zhou ◽  
...  

2018 ◽  
Vol 5 (19) ◽  
pp. 2805-2809 ◽  
Author(s):  
Chang-Bin Yu ◽  
Jie Wang ◽  
Yong-Gui Zhou

A concise synthesis of chiral indolines has been developed through intramolecular condensation, deprotection and palladium-catalyzed asymmetric hydrogenation in a one-pot process with up to 96% ee. A strong Brønsted acid played an important role in both the formation of indoles and asymmetric hydrogenation process.


2019 ◽  
Vol 10 (15) ◽  
pp. 4328-4333 ◽  
Author(s):  
Zhengyu Han ◽  
Gang Liu ◽  
Rui Wang ◽  
Xiu-Qin Dong ◽  
Xumu Zhang

The Ir-catalyzed highly efficient asymmetric hydrogenation of benzoxazinones and derivatives was successfully developed with N-methylated ZhaoPhos L5 as the ligand, affording various chiral dihydrobenzoxazinones and derivatives with excellent results.


2018 ◽  
Vol 91 (8) ◽  
pp. 1252-1257 ◽  
Author(s):  
Yukino Furukawa ◽  
Ryuhei Suzuki ◽  
Tsubasa Nakashima ◽  
Rafael Gramage-Doria ◽  
Kohsuke Ohmatsu ◽  
...  

2012 ◽  
Vol 354 (14-15) ◽  
pp. 2727-2733 ◽  
Author(s):  
Nataliya S. Goulioukina ◽  
Ilya A. Shergold ◽  
Grigorii N. Bondarenko ◽  
Mikhail M. Ilyin ◽  
Vadim A. Davankov ◽  
...  

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