Palladium-Catalyzed Asymmetric Hydrogenation ofN-Hydroxy-α-imino Phosphonates Using Brønsted Acid as Activator: The First Catalytic Enantioselective Approach to ChiralN-Hydroxy-α-amino Phosphonates

2012 ◽  
Vol 354 (14-15) ◽  
pp. 2727-2733 ◽  
Author(s):  
Nataliya S. Goulioukina ◽  
Ilya A. Shergold ◽  
Grigorii N. Bondarenko ◽  
Mikhail M. Ilyin ◽  
Vadim A. Davankov ◽  
...  
Keyword(s):  
Asymmetric Hydrogenation ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Brönsted Acid ◽  
Palladium Catalyzed ◽  
Amino Phosphonates

Facile synthesis of chiral indolines through asymmetric hydrogenation of in situ generated indoles

2018 ◽  
Vol 5 (19) ◽  
pp. 2805-2809 ◽  
Author(s):  
Chang-Bin Yu ◽  
Jie Wang ◽  
Yong-Gui Zhou
Keyword(s):  
Asymmetric Hydrogenation ◽  
Hydrogenation Process ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Facile Synthesis ◽  
One Pot ◽  
Brönsted Acid ◽  
Palladium Catalyzed ◽  
Intramolecular Condensation

A concise synthesis of chiral indolines has been developed through intramolecular condensation, deprotection and palladium-catalyzed asymmetric hydrogenation in a one-pot process with up to 96% ee. A strong Brønsted acid played an important role in both the formation of indoles and asymmetric hydrogenation process.

scholarly journals Highly efficient Ir-catalyzed asymmetric hydrogenation of benzoxazinones and derivatives with a Brønsted acid cocatalyst

2019 ◽  
Vol 10 (15) ◽  
pp. 4328-4333 ◽  
Author(s):  
Zhengyu Han ◽  
Gang Liu ◽  
Rui Wang ◽  
Xiu-Qin Dong ◽  
Xumu Zhang
Keyword(s):  
Asymmetric Hydrogenation ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Highly Efficient ◽  
Brönsted Acid

The Ir-catalyzed highly efficient asymmetric hydrogenation of benzoxazinones and derivatives was successfully developed with N-methylated ZhaoPhos L5 as the ligand, affording various chiral dihydrobenzoxazinones and derivatives with excellent results.

“On water” palladium catalyzed diastereoselective boronic acid addition to structurally diverse cyclopropane nitriles

2020 ◽  
Vol 18 (43) ◽  
pp. 8886-8898
Author(s):  
Dwaipayan Das ◽  
Prasun Mukherjee ◽  
Asish R. Das
Keyword(s):  
Boronic Acid ◽  
Aqueous Media ◽  
Catalytic Amount ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Arylboronic Acids ◽  
Acid Addition ◽  
Brönsted Acid ◽  
Diastereoselective Addition ◽  
Palladium Catalyzed

An efficient palladium catalyzed diastereoselective addition of arylboronic acids to complex spirocyclopropyl dinitriles is developed in the presence of a catalytic amount of DBSA as a Brønsted acid surfactant in aqueous media.

scholarly journals Strong Brønsted acid promoted asymmetric hydrogenation of isoquinolines and quinolines catalyzed by a Rh–thiourea chiral phosphine complex via anion binding

2016 ◽  
Vol 7 (5) ◽  
pp. 3047-3051 ◽  
Author(s):  
Jialin Wen ◽  
Renchang Tan ◽  
Shaodong Liu ◽  
Qingyang Zhao ◽  
Xumu Zhang
Keyword(s):  
Asymmetric Hydrogenation ◽  
Anion Binding ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Brönsted Acid ◽  
Phosphine Complex

Catalyzed by a Rh/bisphosphine–thiourea (L1) complex, isoquinolines and quinolines are hydrogenated with high conversions and high enantioselectivities.

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