scholarly journals A universal platform for building molecular logic circuits based on a reconfigurable three-dimensional DNA nanostructure

2015 ◽  
Vol 6 (6) ◽  
pp. 3556-3564 ◽  
Author(s):  
Kaiyu He ◽  
Yong Li ◽  
Binbin Xiang ◽  
Peng Zhao ◽  
Yufang Hu ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Logic Gates ◽  
Logic Circuits ◽  
Logic Device ◽  
Dna Nanostructure ◽  
Molecular Logic ◽  
Multiple Components

Integrating multiple components of a logic device into a 3D DNA nanoprism provides a universal platform for constructing diverse logic gates.

Target-triggered cascade recycling amplification for label-free detection of microRNA and molecular logic operations

2016 ◽  
Vol 52 (2) ◽  
pp. 402-405 ◽  
Author(s):  
Sai Bi ◽  
Jiayan Ye ◽  
Ying Dong ◽  
Haoting Li ◽  
Wei Cao
Keyword(s):  
Logic Gates ◽  
Logic Circuits ◽  
Label Free ◽  
Chemiluminescence Detection ◽  
Molecular Logic ◽  
Label Free Detection ◽  
Molecular Scale ◽  
Ultrahigh Sensitivity ◽  
Recycling Amplification ◽  
Logic Operations

A cascade recycling amplification (CRA) that implements cascade logic circuits with feedback amplification function is developed for label-free chemiluminescence detection of microRNA-122 with an ultrahigh sensitivity of 0.82 fM and excellent specificity, which is applied to construct a series of molecular-scale two-input logic gates by using microRNAs as inputs and CRA products as outputs.

Logic Devices with Spin Wave Buses - an Approach to Scalable Magneto-Electric Circuitry

2008 ◽  
Vol 1067 ◽  
Author(s):  
Alexander Khitun ◽  
Mingqiang Bao ◽  
Yina Wu ◽  
Ji-Young Kim ◽  
Augustin Hong ◽  
...  
Keyword(s):  
Spin Wave ◽  
Room Temperature ◽  
Logic Gate ◽  
Logic Gates ◽  
Logic Circuits ◽  
Logic Device ◽  
Logic Devices ◽  
Magnetic Circuits ◽  
Micrometer Scale ◽  
Magnetization Signal

ABSTRACTWe analyze spin wave-based logic circuits as a possible route to building reconfigurable magnetic circuits compatible with conventional electron-based devices. A distinctive feature of the spin wave logic circuits is that a bit of information is encoded into the phase of the spin wave. It makes possible to transmit information as a magnetization signal through magnetic waveguides without the use of an electric current. By exploiting sin wave superposition, a set of logic gates such as AND, OR, and Majority gate can be realized in one circuit. We present experimental data illustrating the performance of a three-terminal micrometer scale spin wave-based logic device fabricated on a silicon platform. The device operates in the GHz frequency range and at room temperature. The output power modulation is achieved via the control of the relative phases of two input spin wave signals. The obtained data shows the possibility of using spin waves for achieving logic functionality. The scalability of the spin wave-based logic devices is defined by the wavelength of the spin wave, which depends on the magnetic material and waveguide geometry. Potentially, a multifunctional spin wave logic gate can be scaled down to 0.1μm2. Another potential advantage of the spin wave-based logic circuitry is the ability to implement logic gates with fewer elements as compared to CMOS-based circuits in achieving same functionality. The shortcomings and disadvantages of the spin wave-based devices are also discussed.

scholarly journals 8-Bit Adder and Subtractor with Domain Label Based on DNA Strand Displacement

Molecules ◽  
2018 ◽  
Vol 23 (11) ◽  
pp. 2989 ◽  
Author(s):  
Weixuan Han ◽  
Changjun Zhou
Keyword(s):  
Dna Computing ◽  
Logic Gates ◽  
Logic Circuits ◽  
Calculation Model ◽  
Strand Displacement ◽  
High Concentration ◽  
Low Concentration ◽  
Molecular Logic ◽  
Dna Strand Displacement ◽  
Dna Strand

DNA strand displacement, which plays a fundamental role in DNA computing, has been widely applied to many biological computing problems, including biological logic circuits. However, there are many biological cascade logic circuits with domain labels based on DNA strand displacement that have not yet been designed. Thus, in this paper, cascade 8-bit adder/subtractor with a domain label is designed based on DNA strand displacement; domain t and domain f represent signal 1 and signal 0, respectively, instead of domain t and domain f are applied to representing signal 1 and signal 0 respectively instead of high concentration and low concentration high concentration and low concentration. Basic logic gates, an amplification gate, a fan-out gate and a reporter gate are correspondingly reconstructed as domain label gates. The simulation results of Visual DSD show the feasibility and accuracy of the logic calculation model of the adder/subtractor designed in this paper. It is a useful exploration that may expand the application of the molecular logic circuit.

scholarly journals Constructing Controllable Logic Circuits Based on DNAzyme Activity

Molecules ◽  
2019 ◽  
Vol 24 (22) ◽  
pp. 4134 ◽  
Author(s):  
Fengjie Yang ◽  
Yuan Liu ◽  
Bin Wang ◽  
Changjun Zhou ◽  
Qiang Zhang
Keyword(s):  
Simple Structure ◽  
Logic Gates ◽  
Dna Structure ◽  
Logic Circuits ◽  
Logic Circuit ◽  
Cascade Process ◽  
Activity Regulation ◽  
Basic Logic ◽  
Molecular Logic ◽  
Multi Level

Recently, DNA molecules have been widely used to construct advanced logic devices due to their unique properties, such as a simple structure and predictable behavior. In fact, there are still many challenges in the process of building logic circuits. Among them, the scalability of the logic circuit and the elimination of the crosstalk of the cascade circuit have become the focus of research. Inspired by biological allosteric regulation, we developed a controllable molecular logic circuit strategy based on the activity of DNAzyme. The E6 DNAzyme sequence was temporarily blocked by hairpin DNA and activated under appropriate input trigger conditions. Using a substrate with ribonucleobase (rA) modification as the detection strand, a series of binary basic logic gates (YES, AND, and INHIBIT) were implemented on the computational component platform. At the same time, we demonstrate a parallel demultiplexer and two multi-level cascade circuits (YES-YES and YES-Three input AND (YES-TAND)). In addition, the leakage of the cascade process was reduced by exploring factors such as concentration and DNA structure. The proposed DNAzyme activity regulation strategy provides great potential for the expansion of logic circuits in the future.

Fluorescent Molecular Logic Gates Driven by Temperature and by Protons in Solution and on Solid

2021 ◽  
Author(s):  
Amilra Prasanna de Silva ◽  
Matthew West ◽  
Chao-Yi Yao ◽  
Gavin Melaugh ◽  
Kyoko Kawamoto ◽  
...  
Keyword(s):  
Logic Gates ◽  
Molecular Logic ◽  
Molecular Logic Gates

Synthesis and spectral investigation of colorimetric receptors for the dual detection of copper and acetate ions: application in molecular logic gates

2017 ◽  
Vol 29 (8) ◽  
pp. 561-574 ◽  
Author(s):  
Srikala Pangannaya ◽  
Arshiya Kaur ◽  
Makesh Mohan ◽  
Keyur Raval ◽  
Dillip Kumar Chand ◽  
...  
Keyword(s):  
Logic Gates ◽  
Spectral Investigation ◽  
Molecular Logic ◽  
Molecular Logic Gates ◽  
Dual Detection

Design of fully photonic molecular logic gates based on the supramolecular bis-styrylquinoline dyad

2012 ◽  
Vol 7 (5-6) ◽  
pp. 280-287 ◽  
Author(s):  
M. F. Budyka ◽  
N. I. Potashova ◽  
T. N. Gavrishova ◽  
V. M. Li
Keyword(s):  
Logic Gates ◽  
Molecular Logic ◽  
Molecular Logic Gates
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