scholarly journals Molecular Logic: From Single Logic Gates to Sophisticated Logic Circuits, from Fundamental Science to Practical Applications

ChemPhysChem ◽  
2017 ◽  
Vol 18 (13) ◽  
pp. 1665-1666 ◽  
Author(s):  
Engin Umut Akkaya ◽  
Evgeny Katz ◽  
Uwe Pischel
Keyword(s):  
Logic Gates ◽  
Logic Circuits ◽  
Practical Applications ◽  
Molecular Logic ◽  
Fundamental Science

Target-triggered cascade recycling amplification for label-free detection of microRNA and molecular logic operations

2016 ◽  
Vol 52 (2) ◽  
pp. 402-405 ◽  
Author(s):  
Sai Bi ◽  
Jiayan Ye ◽  
Ying Dong ◽  
Haoting Li ◽  
Wei Cao
Keyword(s):  
Logic Gates ◽  
Logic Circuits ◽  
Label Free ◽  
Chemiluminescence Detection ◽  
Molecular Logic ◽  
Label Free Detection ◽  
Molecular Scale ◽  
Ultrahigh Sensitivity ◽  
Recycling Amplification ◽  
Logic Operations

A cascade recycling amplification (CRA) that implements cascade logic circuits with feedback amplification function is developed for label-free chemiluminescence detection of microRNA-122 with an ultrahigh sensitivity of 0.82 fM and excellent specificity, which is applied to construct a series of molecular-scale two-input logic gates by using microRNAs as inputs and CRA products as outputs.

scholarly journals 8-Bit Adder and Subtractor with Domain Label Based on DNA Strand Displacement

Molecules ◽  
2018 ◽  
Vol 23 (11) ◽  
pp. 2989 ◽  
Author(s):  
Weixuan Han ◽  
Changjun Zhou
Keyword(s):  
Dna Computing ◽  
Logic Gates ◽  
Logic Circuits ◽  
Calculation Model ◽  
Strand Displacement ◽  
High Concentration ◽  
Low Concentration ◽  
Molecular Logic ◽  
Dna Strand Displacement ◽  
Dna Strand

DNA strand displacement, which plays a fundamental role in DNA computing, has been widely applied to many biological computing problems, including biological logic circuits. However, there are many biological cascade logic circuits with domain labels based on DNA strand displacement that have not yet been designed. Thus, in this paper, cascade 8-bit adder/subtractor with a domain label is designed based on DNA strand displacement; domain t and domain f represent signal 1 and signal 0, respectively, instead of domain t and domain f are applied to representing signal 1 and signal 0 respectively instead of high concentration and low concentration high concentration and low concentration. Basic logic gates, an amplification gate, a fan-out gate and a reporter gate are correspondingly reconstructed as domain label gates. The simulation results of Visual DSD show the feasibility and accuracy of the logic calculation model of the adder/subtractor designed in this paper. It is a useful exploration that may expand the application of the molecular logic circuit.

scholarly journals Constructing Controllable Logic Circuits Based on DNAzyme Activity

Molecules ◽  
2019 ◽  
Vol 24 (22) ◽  
pp. 4134 ◽  
Author(s):  
Fengjie Yang ◽  
Yuan Liu ◽  
Bin Wang ◽  
Changjun Zhou ◽  
Qiang Zhang
Keyword(s):  
Simple Structure ◽  
Logic Gates ◽  
Dna Structure ◽  
Logic Circuits ◽  
Logic Circuit ◽  
Cascade Process ◽  
Activity Regulation ◽  
Basic Logic ◽  
Molecular Logic ◽  
Multi Level

Recently, DNA molecules have been widely used to construct advanced logic devices due to their unique properties, such as a simple structure and predictable behavior. In fact, there are still many challenges in the process of building logic circuits. Among them, the scalability of the logic circuit and the elimination of the crosstalk of the cascade circuit have become the focus of research. Inspired by biological allosteric regulation, we developed a controllable molecular logic circuit strategy based on the activity of DNAzyme. The E6 DNAzyme sequence was temporarily blocked by hairpin DNA and activated under appropriate input trigger conditions. Using a substrate with ribonucleobase (rA) modification as the detection strand, a series of binary basic logic gates (YES, AND, and INHIBIT) were implemented on the computational component platform. At the same time, we demonstrate a parallel demultiplexer and two multi-level cascade circuits (YES-YES and YES-Three input AND (YES-TAND)). In addition, the leakage of the cascade process was reduced by exploring factors such as concentration and DNA structure. The proposed DNAzyme activity regulation strategy provides great potential for the expansion of logic circuits in the future.

scholarly journals Molecular logic gates: the past, present and future

2018 ◽  
Vol 47 (7) ◽  
pp. 2228-2248 ◽  
Author(s):  
Sundus Erbas-Cakmak ◽  
Safacan Kolemen ◽  
Adam C. Sedgwick ◽  
Thorfinnur Gunnlaugsson ◽  
Tony D. James ◽  
...  
Keyword(s):  
Logic Gates ◽  
Practical Applications ◽  
The Past ◽  
Molecular Logic ◽  
Molecular Logic Gates

Molecular logic gates, now with more than two decades of collective exploration, are poised for practical applications.

scholarly journals A universal platform for building molecular logic circuits based on a reconfigurable three-dimensional DNA nanostructure

2015 ◽  
Vol 6 (6) ◽  
pp. 3556-3564 ◽  
Author(s):  
Kaiyu He ◽  
Yong Li ◽  
Binbin Xiang ◽  
Peng Zhao ◽  
Yufang Hu ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Logic Gates ◽  
Logic Circuits ◽  
Logic Device ◽  
Dna Nanostructure ◽  
Molecular Logic ◽  
Multiple Components

Integrating multiple components of a logic device into a 3D DNA nanoprism provides a universal platform for constructing diverse logic gates.

scholarly journals Electrically driven formation and dynamics of Pac-Man solitons in smectic A liquid crystals

2021 ◽  
Author(s):  
Yuan Shen ◽  
Ingo Dierking
Keyword(s):  
Liquid Crystals ◽  
Electric Field ◽  
Spatiotemporal Chaos ◽  
Practical Applications ◽  
Smectic A ◽  
Fundamental Science ◽  
Smectic A Liquid Crystals

Electric field driven instabilities of liquid crystals, such as electro-convections, spatiotemporal chaos, backflows, and solitons are of great importance for both fundamental science and practical applications. Here we demonstrate that...

Fluorescent Molecular Logic Gates Driven by Temperature and by Protons in Solution and on Solid

2021 ◽  
Author(s):  
Amilra Prasanna de Silva ◽  
Matthew West ◽  
Chao-Yi Yao ◽  
Gavin Melaugh ◽  
Kyoko Kawamoto ◽  
...  
Keyword(s):  
Logic Gates ◽  
Molecular Logic ◽  
Molecular Logic Gates

Synthesis and spectral investigation of colorimetric receptors for the dual detection of copper and acetate ions: application in molecular logic gates

2017 ◽  
Vol 29 (8) ◽  
pp. 561-574 ◽  
Author(s):  
Srikala Pangannaya ◽  
Arshiya Kaur ◽  
Makesh Mohan ◽  
Keyur Raval ◽  
Dillip Kumar Chand ◽  
...  
Keyword(s):  
Logic Gates ◽  
Spectral Investigation ◽  
Molecular Logic ◽  
Molecular Logic Gates ◽  
Dual Detection

Design of fully photonic molecular logic gates based on the supramolecular bis-styrylquinoline dyad

2012 ◽  
Vol 7 (5-6) ◽  
pp. 280-287 ◽  
Author(s):  
M. F. Budyka ◽  
N. I. Potashova ◽  
T. N. Gavrishova ◽  
V. M. Li
Keyword(s):  
Logic Gates ◽  
Molecular Logic ◽  
Molecular Logic Gates
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