Biocompatible degradable injectable hydrogels from methacrylated poly(ethylene glycol)-co-poly(xylitol sebacate) and cyclodextrins for release of hydrophilic and hydrophobic drugs

RSC Advances ◽  
2015 ◽  
Vol 5 (82) ◽  
pp. 66965-66974 ◽  
Author(s):  
Mengyao Zhang ◽  
Yaobin Wu ◽  
Xin Zhao ◽  
Kun Gao ◽  
Peter X. Ma ◽  
...  
Keyword(s):  
Drug Release ◽  
Ethylene Glycol ◽  
Composite Hydrogel ◽  
Hydrophobic Drugs ◽  
Hydrophobic Drug ◽  
Poly Ethylene Glycol ◽  
Injectable Hydrogels ◽  
Poly Ethylene

An injectable photocurable composite hydrogel from methacrylated poly(ethylene glycol)-co-poly(xylitol sebacate) (PEGXS-M) and acrylamidomethyl-β-cyclodextrin (β-CD-NMA) for both hydrophilic and hydrophobic drug release.

Temperature-responsive in situ nanoparticle hydrogels based on hydrophilic pendant cyclic ether modified PEG-PCL-PEG

2016 ◽  
Vol 4 (10) ◽  
pp. 1493-1502 ◽  
Author(s):  
Zujian Feng ◽  
Junqiang Zhao ◽  
Yin Li ◽  
Shuxin Xu ◽  
Junhui Zhou ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Drug Release ◽  
Ethylene Glycol ◽  
Cyclic Ether ◽  
Poly Ethylene Glycol ◽  
Sustained Drug Release ◽  
Injectable Hydrogels ◽  
Temperature Responsive ◽  
Poly Ethylene

Thermo-sensitive injectable hydrogels based on poly(ε-caprolactone)/poly(ethylene glycol) (PCL/PEG) block copolymers have attracted considerable attention for sustained drug release and tissue engineering applications.

Reversibly cross-linked poly(ethylene glycol)–poly(amino acid)s copolymer micelles: a promising approach to overcome the extracellular stability versus intracellular drug release challenge

RSC Advances ◽  
2015 ◽  
Vol 5 (26) ◽  
pp. 20025-20034 ◽  
Author(s):  
Yuling Li ◽  
Sai Wang ◽  
Dandan Zhu ◽  
Yuling Shen ◽  
Baixiang Du ◽  
...  
Keyword(s):  
Amino Acid ◽  
Drug Release ◽  
Ethylene Glycol ◽  
Lipoic Acid ◽  
Triblock Copolymer ◽  
Intracellular Delivery ◽  
Poly Ethylene Glycol ◽  
Copolymer Micelles ◽  
Poly Ethylene ◽  
Copolymer Poly

Reversibly shell cross-linked micelles based on a lipoic acid (LA) decorated triblock copolymer poly(ethylene glycol)-b-poly(γ-benzyl-l-glutamate)-b-poly(l-phenylalanine) have been developed for efficient intracellular delivery of DOX.

Controlled Release Behaviors of Ketoprofen from Matrix Polymer of Chitosan and poly(ethylene glycol)

2013 ◽  
Vol 813 ◽  
pp. 399-402
Author(s):  
Chimsook Thitipha ◽  
Thitiphan Chimsook
Keyword(s):  
Particle Size ◽  
Controlled Release ◽  
Drug Release ◽  
Ethylene Glycol ◽  
Diffusion Method ◽  
Poly Ethylene Glycol ◽  
Matrix Polymer ◽  
Percentage Yield ◽  
Poly Ethylene ◽  
Composition Ratios

The aim of present work was to prepare floating microsphere of ketoprofen using matrix polymer of chitosan and poly (ethylene glycol) by solvent diffusion method. The floating microsphere of ketoprofen was prepared from matrix polymer of chitosan and poly (ethylene glycol) with various composition ratios and evaluated such as particle size, drug compatibility and drug release of microspheres. The scanning electron microscopy of microspheres confirmed their hollow structures with smooth surface. Formulation CPK 4 to CPK 6 exhibited the best controlled release pattern in ketoprofen. The concentration and size of poly (ethylene-glycol) affected the particle size, percentage yield and drug release of microspheres.

scholarly journals High-Performance Resistive Pressure Sensor Based on Elastic Composite Hydrogel of Silver Nanowires and Poly(ethylene glycol)

Micromachines ◽  
2018 ◽  
Vol 9 (9) ◽  
pp. 438 ◽  
Author(s):  
Youngsang Ko ◽  
Dabum Kim ◽  
Goomin Kwon ◽  
Jungmok You
Keyword(s):  
Composite Material ◽  
Ethylene Glycol ◽  
Pressure Sensor ◽  
High Performance ◽  
Silver Nanowires ◽  
High Sensitivity ◽  
Composite Hydrogel ◽  
Poly Ethylene Glycol ◽  
Pressure Sensing ◽  
Poly Ethylene

Improved pressure sensing is of great interest to enable the next-generation of bioelectronics systems. This paper describes the development of a transparent, flexible, highly sensitive pressure sensor, having a composite sandwich structure of elastic silver nanowires (AgNWs) and poly(ethylene glycol) (PEG). A simple PEG photolithography was employed to construct elastic AgNW-PEG composite patterns on flexible polyethylene terephthalate (PET) film. A porous PEG hydrogel structure enabled the use of conductive AgNW patterns while maintaining the elasticity of the composite material, features that are both essential for high-performance pressure sensing. The transparency and electrical properties of AgNW-PEG composite could be precisely controlled by varying the AgNW concentration. An elastic AgNW-PEG composite hydrogel with 0.6 wt % AgNW concentration exhibited high transmittance including T550nm of around 86%, low sheet resistance of 22.69 Ω·sq−1, and excellent bending durability (only 5.8% resistance increase under bending to 10 mm radius). A flexible resistive pressure sensor based on our highly transparent AgNW-PEG composite showed stable and reproducible response, high sensitivity (69.7 kPa−1), low sensing threshold (~2 kPa), and fast response time (20–40 ms), demonstrating the effectiveness of the AgNW-PEG composite material as an elastic conductor.

Therapeutic effects of boronate ester cross-linked injectable hydrogels for the treatment of hepatocellular carcinoma

2021 ◽  
Author(s):  
Jae Min Jung ◽  
Seong Han Kim ◽  
V. H. Giang Phan ◽  
Thavasyappan Thambi ◽  
Doo Sung Lee
Keyword(s):  
Hepatocellular Carcinoma ◽  
Ethylene Glycol ◽  
Therapeutic Effects ◽  
Poly Ethylene Glycol ◽  
Injectable Hydrogels ◽  
High Incidence ◽  
High Incidence Rate ◽  
The Common ◽  
Poly Ethylene ◽  
Responsive Hydrogels

Hepatocellular carcinoma is the common malignant with a high incidence rate and responsible for the highest cause of cancer-related deaths. Herein, we developed a thermo-responsive hydrogels comprised of poly(ε-caprolactone-co-lactide)-b-poly(ethylene glycol)-b-poly(ε-caprolactone-co-lactide...

scholarly journals Hydrolysis and drug release from poly(ethylene glycol)-modified lactone polymers with open porosity

2019 ◽  
Vol 113 ◽  
pp. 165-175 ◽  
Author(s):  
Sanja Asikainen ◽  
Kaarlo Paakinaho ◽  
Anna-Kaisa Kyhkynen ◽  
Markus Hannula ◽  
Minna Malin ◽  
...  
Keyword(s):  
Drug Release ◽  
Ethylene Glycol ◽  
Open Porosity ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Star-shaped poly(l-lactide)-b-poly(ethylene glycol) with porphyrin core: synthesis, self-assembly, drug-release behavior and singlet oxygen research

2014 ◽  
Vol 38 (8) ◽  
pp. 3569-3578 ◽  
Author(s):  
Xiao-Hui Dai ◽  
Zhi-Ming Wang ◽  
Lu-You Gao ◽  
Jian-Ming Pan ◽  
Xiao-Hong Wang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Block Copolymer ◽  
Drug Release ◽  
Ethylene Glycol ◽  
Self Assembly ◽  
Release Behavior ◽  
Poly Ethylene Glycol ◽  
Drug Release Behavior ◽  
Porphyrin Core ◽  
Poly Ethylene

pH-induced block copolymer SPPLA-b-PEG with porphyrin core for photodynamic therapy.

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