Development and application of a nanocomposite derived from crosslinked HPMC and Au nanoparticles for colon targeted drug delivery

RSC Advances ◽  
2015 ◽  
Vol 5 (35) ◽  
pp. 27481-27490 ◽  
Author(s):  
Raghunath Das ◽  
Dipankar Das ◽  
Paulomi Ghosh ◽  
Santanu Dhara ◽  
Asit Baran Panda ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Au Nanoparticles ◽  
Methyl Cellulose ◽  
Reducing Agent ◽  
Hydroxypropyl Methyl Cellulose ◽  
Targeted Drug ◽  
Poly Acrylamide

Herein, we report a novel route for the synthesis of poly(acrylamide) (PAAm) crosslinked hydroxypropyl methyl cellulose/Au nanocomposite where chemically crosslinked HPMC (c-HPMC) works as a reducing agent.

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