Heterogeneous core/shell fluoride nanocrystals with enhanced upconversion photoluminescence for in vivo bioimaging

Nanoscale ◽  
2015 ◽  
Vol 7 (24) ◽  
pp. 10775-10780 ◽  
Author(s):  
Shuwei Hao ◽  
Liming Yang ◽  
Hailong Qiu ◽  
Rongwei Fan ◽  
Chunhui Yang ◽  
...  
Keyword(s):  
Core Shell ◽  
Upconversion Photoluminescence

scholarly journals Silica-Coated Fe3O4 Nanoparticles as a Bifunctional Agent for Magnetic Resonance Imaging and ZnII Fluorescent Sensing

2021 ◽  
Vol 20 ◽  
pp. 153303382110365
Author(s):  
Lin Qiu ◽  
Shuwen Zhou ◽  
Ying Li ◽  
Wen Rui ◽  
Pengfei Cui ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agent ◽  
Quantum Interference ◽  
Inductively Coupled Plasma ◽  
Fluorescence Emission ◽  
Mri Contrast Agent ◽  
Core Shell ◽  
Resonance Imaging

Bifunctional magnetic/fluorescent core-shell silica nanospheres (MNPs) encapsulated with the magnetic Fe3O4 core and a derivate of 8-amimoquinoline (N-(quinolin-8-yl)-2-(3-(triethoxysilyl) propylamino) acetamide) (QTEPA) into the shell were synthesized. These functional MNPs were prepared with a modified stöber method and the formed Fe3O4@SiO2-QTEPA core-shell nanocomposites are biocompatible, water-dispersible, and stable. These prepared nanoparticles were characterized by X-ray power diffraction (XRD), transmission electron microscopy (TEM), thermoelectric plasma Quad II inductively coupled plasma mass spectrometry (ICP-MS), superconducting quantum interference device (SQUID), TG/DTA thermal analyzer (TGA) and Fourier transform infrared spectroscopy (FTIR). Further application of the nanoparticles in detecting Zn2+ was confirmed by the fluorescence experiment: the nanosensor shows high selectivity and sensitivity to Zn2+ with a 22-fold fluorescence emission enhancement in the presence of 10 μM Zn2+. Moreover, the transverse relaxivity measurements show that the core-shell MNPs have T2 relaxivity (r2) of 155.05 mM−1 S−1 based on Fe concentration on the 3.0 T scanner, suggesting that the compound can be used as a negative contrast agent for MRI. Further in vivo experiments showed that these MNPs could be used as MRI contrast agent. Therefore, the new nanosensor provides the dual modality of magnetic resonance imaging and optical imaging.

Core-Shell Pd@Au Nanoplates as Theranostic Agents for In-Vivo Photoacoustic Imaging, CT Imaging, and Photothermal Therapy

2014 ◽  
Vol 26 (48) ◽  
pp. 8210-8216 ◽  
Author(s):  
Mei Chen ◽  
Shaoheng Tang ◽  
Zhide Guo ◽  
Xiaoyong Wang ◽  
Shiguang Mo ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Ct Imaging ◽  
Core Shell ◽  
Theranostic Agents

The one-pot synthesis of core/shell/shell CdTe/CdSe/ZnSe quantum dots in aqueous media for in vivo deep tissue imaging

2011 ◽  
Vol 21 (9) ◽  
pp. 2877 ◽  
Author(s):  
Shohei Taniguchi ◽  
Mark Green ◽  
Sarwat B. Rizvi ◽  
Alexander Seifalian
Keyword(s):  
Quantum Dots ◽  
Aqueous Media ◽  
Tissue Imaging ◽  
Core Shell ◽  
Deep Tissue ◽  
One Pot ◽  
One Pot Synthesis ◽  
Deep Tissue Imaging ◽  
The One

scholarly journals Size Series of Small Indium Arsenide−Zinc Selenide Core−Shell Nanocrystals and Their Application to In Vivo Imaging

2006 ◽  
Vol 128 (8) ◽  
pp. 2526-2527 ◽  
Author(s):  
John P. Zimmer ◽  
Sang-Wook Kim ◽  
Shunsuke Ohnishi ◽  
Eichii Tanaka ◽  
John V. Frangioni ◽  
...  
Keyword(s):  
Zinc Selenide ◽  
Indium Arsenide ◽  
In Vivo Imaging ◽  
Core Shell ◽  
Size Series

Realizing highly chemoselective detection of H2S in vitro and in vivo with fluorescent probes inside core-shell silica nanoparticles

Biomaterials ◽  
2018 ◽  
Vol 159 ◽  
pp. 82-90 ◽  
Author(s):  
Feiyi Wang ◽  
Ge Xu ◽  
Xianfeng Gu ◽  
Zhijun Wang ◽  
Zhiqiang Wang ◽  
...  
Keyword(s):  
Silica Nanoparticles ◽  
Fluorescent Probes ◽  
Core Shell

Smart assembly of Mn-ferrites/silica core–shell with fluorescein and gold nanorods: robust and stable nanomicelles for in vivo triple modality imaging

2018 ◽  
Vol 6 (19) ◽  
pp. 2993-2999 ◽  
Author(s):  
Ilaria Monaco ◽  
Paolo Armanetti ◽  
Erica Locatelli ◽  
Alessandra Flori ◽  
Mirko Maturi ◽  
...  
Keyword(s):  
Gold Nanorods ◽  
Core Shell ◽  
Smart Assembly ◽  
Silica Core

We report the synthesis of a resilient nanosystem (MnFe2O4@SiO2@GNRs@PMs) for magnetic–photoacoustic–optical triple-modality imaging.

Core@shell structured ceria@mesoporous silica nanoantibiotics restrain bacterial growth in vitro and in vivo

2021 ◽  
pp. 112607
Author(s):  
Didem Şen Karaman ◽  
Christa Kietz ◽  
Prakirth Govardhanam ◽  
Anna Slita ◽  
Alexandra Manea ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Bacterial Growth ◽  
Core Shell

scholarly journals Docosahexaenoic Acid-Loaded Polylactic Acid Core-Shell Nanofiber Membranes for Regenerative Medicine after Spinal Cord Injury: In Vitro and In Vivo Study

2020 ◽  
Vol 21 (19) ◽  
pp. 7031
Author(s):  
Zhuo-Hao Liu ◽  
Yin-Cheng Huang ◽  
Chang-Yi Kuo ◽  
Chao-Ying Kuo ◽  
Chieh-Yu Chin ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Docosahexaenoic Acid ◽  
Neurite Outgrowth ◽  
Polylactic Acid ◽  
In Vivo Study ◽  
Core Shell ◽  
Cord Injury

Spinal cord injury (SCI) is associated with disability and a drastic decrease in quality of life for affected individuals. Previous studies support the idea that docosahexaenoic acid (DHA)-based pharmacological approach is a promising therapeutic strategy for the management of acute SCI. We postulated that a nanostructured material for controlled delivery of DHA at the lesion site may be well suited for this purpose. Toward this end, we prepare drug-loaded fibrous mats made of core-shell nanofibers by electrospinning, which contained a polylactic acid (PLA) shell for encapsulation of DHA within the core, for delivery of DHA in situ. In vitro study confirmed sustained DHA release from PLA/DHA core-shell nanofiber membrane (CSNM) for up to 36 days, which could significantly increase neurite outgrowth from primary cortical neurons in 3 days. This is supported by the upregulation of brain-derived neurotropic factor (BDNF) and neurotrophin-3 (NT-3) neural marker genes from qRT-PCR analysis. Most importantly, the sustained release of DHA could significantly increase the neurite outgrowth length from cortical neuron cells in 7 days when co-cultured with PLA/DHA CSNM, compared with cells cultured with 3 μM DHA. From in vivo study with a SCI model created in rats, implantation of PLA/DHA CSNM could significantly improve neurological functions revealed by behavior assessment in comparison with the control (no treatment) and the PLA CSNM groups. According to histological analysis, PLA/DHA CSNM also effectively reduced neuron loss and increased serotonergic nerve sprouting. Taken together, the PLA/DHA CSNM may provide a nanostructured drug delivery system for DHA and contribute to neuroprotection and promoting neuroplasticity change following SCI.

scholarly journals Dye-doped biodegradable nanoparticle SiO2 coating on zinc- and iron-oxide nanoparticles to improve biocompatibility and for in vivo imaging studies

Nanoscale ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 6164-6175 ◽  
Author(s):  
Elena Navarro-Palomares ◽  
Paula González-Saiz ◽  
Carlos Renero-Lecuna ◽  
Rosa Martín-Rodríguez ◽  
Fernando Aguado ◽  
...  
Keyword(s):  
Iron Oxide ◽  
In Vivo Imaging ◽  
Oxide Nanoparticles ◽  
Core Shell ◽  
Imaging Studies ◽  
Sio2 Coating ◽  
Shell Nanoparticles ◽  
Nano Medicine ◽  
Core Shell Nanoparticles

Core–shell nanoparticles provide two fold functionality in nano medicine: reduction of nanotoxicity and improving as a tool for imaging and therapy.

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