Smart assembly of Mn-ferrites/silica core–shell with fluorescein and gold nanorods: robust and stable nanomicelles for in vivo triple modality imaging

2018 ◽  
Vol 6 (19) ◽  
pp. 2993-2999 ◽  
Author(s):  
Ilaria Monaco ◽  
Paolo Armanetti ◽  
Erica Locatelli ◽  
Alessandra Flori ◽  
Mirko Maturi ◽  
...  
Keyword(s):  
Gold Nanorods ◽  
Core Shell ◽  
Smart Assembly ◽  
Silica Core

We report the synthesis of a resilient nanosystem (MnFe2O4@SiO2@GNRs@PMs) for magnetic–photoacoustic–optical triple-modality imaging.

scholarly journals Plasmonic photothermal cancer therapy with gold nanorods/reduced graphene oxide core/shell nanocomposites

RSC Advances ◽  
2016 ◽  
Vol 6 (2) ◽  
pp. 1600-1610 ◽  
Author(s):  
Kostiantyn Turcheniuk ◽  
Tetiana Dumych ◽  
Rostyslav Bilyy ◽  
Volodymyr Turcheniuk ◽  
Julie Bouckaert ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Cancer Therapy ◽  
Reduced Graphene Oxide ◽  
Photon Energy ◽  
Gold Nanorods ◽  
Core Shell ◽  
Efficient Conversion ◽  
Reduced Graphene

Gold nanorods (Au NRs) are known for their efficient conversion of photon energy into heat, resulting in hyperthermia and suppression of tumor growths in vitro and in vivo.

Preparation of Zirconia Silica Core Shell Microspheres and Its Application for Highly Specific Phospholipids Enrichment

2013 ◽  
Vol 41 (8) ◽  
pp. 1214
Author(s):  
Kai YAO ◽  
Yun XUE ◽  
Qian WU ◽  
Jing LI ◽  
Yan WANG ◽  
...  
Keyword(s):  
Core Shell ◽  
Silica Core

scholarly journals Silica-Coated Fe3O4 Nanoparticles as a Bifunctional Agent for Magnetic Resonance Imaging and ZnII Fluorescent Sensing

2021 ◽  
Vol 20 ◽  
pp. 153303382110365
Author(s):  
Lin Qiu ◽  
Shuwen Zhou ◽  
Ying Li ◽  
Wen Rui ◽  
Pengfei Cui ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agent ◽  
Quantum Interference ◽  
Inductively Coupled Plasma ◽  
Fluorescence Emission ◽  
Mri Contrast Agent ◽  
Core Shell ◽  
Resonance Imaging

Bifunctional magnetic/fluorescent core-shell silica nanospheres (MNPs) encapsulated with the magnetic Fe3O4 core and a derivate of 8-amimoquinoline (N-(quinolin-8-yl)-2-(3-(triethoxysilyl) propylamino) acetamide) (QTEPA) into the shell were synthesized. These functional MNPs were prepared with a modified stöber method and the formed Fe3O4@SiO2-QTEPA core-shell nanocomposites are biocompatible, water-dispersible, and stable. These prepared nanoparticles were characterized by X-ray power diffraction (XRD), transmission electron microscopy (TEM), thermoelectric plasma Quad II inductively coupled plasma mass spectrometry (ICP-MS), superconducting quantum interference device (SQUID), TG/DTA thermal analyzer (TGA) and Fourier transform infrared spectroscopy (FTIR). Further application of the nanoparticles in detecting Zn2+ was confirmed by the fluorescence experiment: the nanosensor shows high selectivity and sensitivity to Zn2+ with a 22-fold fluorescence emission enhancement in the presence of 10 μM Zn2+. Moreover, the transverse relaxivity measurements show that the core-shell MNPs have T2 relaxivity (r2) of 155.05 mM−1 S−1 based on Fe concentration on the 3.0 T scanner, suggesting that the compound can be used as a negative contrast agent for MRI. Further in vivo experiments showed that these MNPs could be used as MRI contrast agent. Therefore, the new nanosensor provides the dual modality of magnetic resonance imaging and optical imaging.

scholarly journals Amyloid fibril-directed synthesis of silica core–shell nanofilaments, gels, and aerogels

2019 ◽  
Vol 116 (10) ◽  
pp. 4012-4017 ◽  
Author(s):  
Yiping Cao ◽  
Sreenath Bolisetty ◽  
Gianna Wolfisberg ◽  
Jozef Adamcik ◽  
Raffaele Mezzenga
Keyword(s):  
Amyloid Fibril ◽  
Functional Materials ◽  
Building Blocks ◽  
Inorganic Materials ◽  
Core Shell ◽  
Shear Stresses ◽  
Bending Rigidity ◽  
Widespread Application ◽  
Nonmonotonic Dependence ◽  
Silica Core

Amyloid fibrils have evolved from purely pathological materials implicated in neurodegenerative diseases to efficient templates for last-generation functional materials and nanotechnologies. Due to their high intrinsic stiffness and extreme aspect ratio, amyloid fibril hydrogels can serve as ideal building blocks for material design and synthesis. Yet, in these gels, stiffness is generally not paired by toughness, and their fragile nature hinders significantly their widespread application. Here we introduce an amyloid-assisted biosilicification process, which leads to the formation of silicified nanofibrils (fibril–silica core–shell nanofilaments) with stiffness up to and beyond ∼20 GPa, approaching the Young’s moduli of many metal alloys and inorganic materials. The silica shell endows the silicified fibrils with large bending rigidity, reflected in hydrogels with elasticity three orders of magnitude beyond conventional amyloid fibril hydrogels. A constitutive theoretical model is proposed that, despite its simplicity, quantitatively interprets the nonmonotonic dependence of the gel elasticity upon the filaments bundling promoted by shear stresses. The application of these hybrid silica–amyloid hydrogels is demonstrated on the fabrication of mechanically stable aerogels generated via sequential solvent exchange, supercriticalCO2removal, and calcination of the amyloid core, leading to aerogels of specific surface area as high as 993m2/g, among the highest values ever reported for aerogels. We finally show that the scope of amyloid hydrogels can be expanded considerably by generating double networks of amyloid and hydrophilic polymers, which combine excellent stiffness and toughness beyond those of each of the constitutive individual networks.

Core-Shell Pd@Au Nanoplates as Theranostic Agents for In-Vivo Photoacoustic Imaging, CT Imaging, and Photothermal Therapy

2014 ◽  
Vol 26 (48) ◽  
pp. 8210-8216 ◽  
Author(s):  
Mei Chen ◽  
Shaoheng Tang ◽  
Zhide Guo ◽  
Xiaoyong Wang ◽  
Shiguang Mo ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Ct Imaging ◽  
Core Shell ◽  
Theranostic Agents
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