scholarly journals Size Series of Small Indium Arsenide−Zinc Selenide Core−Shell Nanocrystals and Their Application to In Vivo Imaging

2006 ◽  
Vol 128 (8) ◽  
pp. 2526-2527 ◽  
Author(s):  
John P. Zimmer ◽  
Sang-Wook Kim ◽  
Shunsuke Ohnishi ◽  
Eichii Tanaka ◽  
John V. Frangioni ◽  
...  
Keyword(s):  
Zinc Selenide ◽  
Indium Arsenide ◽  
In Vivo Imaging ◽  
Core Shell ◽  
Size Series

scholarly journals Dye-doped biodegradable nanoparticle SiO2 coating on zinc- and iron-oxide nanoparticles to improve biocompatibility and for in vivo imaging studies

Nanoscale ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 6164-6175 ◽  
Author(s):  
Elena Navarro-Palomares ◽  
Paula González-Saiz ◽  
Carlos Renero-Lecuna ◽  
Rosa Martín-Rodríguez ◽  
Fernando Aguado ◽  
...  
Keyword(s):  
Iron Oxide ◽  
In Vivo Imaging ◽  
Oxide Nanoparticles ◽  
Core Shell ◽  
Imaging Studies ◽  
Sio2 Coating ◽  
Shell Nanoparticles ◽  
Nano Medicine ◽  
Core Shell Nanoparticles

Core–shell nanoparticles provide two fold functionality in nano medicine: reduction of nanotoxicity and improving as a tool for imaging and therapy.

Preparation of core/shell NaYF 4 :Yb,Tm@dendrons nanoparticles with enhanced upconversion luminescence for in vivo imaging

2016 ◽  
Vol 12 (7) ◽  
pp. 2107-2113 ◽  
Author(s):  
Nadège Francolon ◽  
Damien Boyer ◽  
Felicia Leccia ◽  
Elodie Jouberton ◽  
Aurélie Walter ◽  
...  
Keyword(s):  
In Vivo Imaging ◽  
Upconversion Luminescence ◽  
Core Shell

Ultra-bright near-infrared-emitting HgS/ZnS core/shell nanocrystals for in vitro and in vivo imaging

2015 ◽  
Vol 3 (34) ◽  
pp. 6928-6938 ◽  
Author(s):  
Jing Yang ◽  
Yaoping Hu ◽  
Jiangwei Tan ◽  
Li Jia ◽  
Yu-Hua Zhu ◽  
...  
Keyword(s):  
In Vivo Imaging ◽  
Near Infrared ◽  
Core Shell ◽  
Good Biocompatibility

Novel ultra-bright, stable NIR-emitting HgS/ZnS core/shell NCs with good biocompatibility for in vitro and in vivo imaging.

Magnetic-NIR Persistent Luminescent Dual-Modal ZGOCS@MSNs@Gd2O3 Core–Shell Nanoprobes For In Vivo Imaging

2017 ◽  
Vol 29 (9) ◽  
pp. 3938-3946 ◽  
Author(s):  
Rui Zou ◽  
Shuming Gong ◽  
Junpeng Shi ◽  
Ju Jiao ◽  
Ka-Leung Wong ◽  
...  
Keyword(s):  
In Vivo Imaging ◽  
Core Shell

Synthesis and Characterization of Near-Infrared Cu−In−Se/ZnS Core/Shell Quantum Dots for In vivo Imaging

2010 ◽  
Vol 22 (22) ◽  
pp. 6117-6124 ◽  
Author(s):  
E. Cassette ◽  
T. Pons ◽  
C. Bouet ◽  
M. Helle ◽  
L. Bezdetnaya ◽  
...  
Keyword(s):  
Quantum Dots ◽  
In Vivo Imaging ◽  
Near Infrared ◽  
Synthesis And Characterization ◽  
Core Shell

scholarly journals Rapidly liver-clearable rare-earth core–shell nanoprobe for dual-modal breast cancer imaging in the second near-infrared window

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Zhuxin Wei ◽  
Guangxin Duan ◽  
Baoxing Huang ◽  
Shanshan Qiu ◽  
Dandan Zhou ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Rare Earth ◽  
In Vivo Imaging ◽  
Near Infrared ◽  
Preoperative Imaging ◽  
Core Shell ◽  
High Background ◽  
Earth Core

Abstract Background Fluorescence imaging as the beacon for optical navigation has wildly developed in preclinical studies due to its prominent advantages, including noninvasiveness and superior temporal resolution. However, the traditional optical methods based on ultraviolet (UV, 200–400 nm) and visible light (Vis, 400–650 nm) limited by their low penetration, signal-to-noise ratio, and high background auto-fluorescence interference. Therefore, the development of near-infrared-II (NIR-II 1000–1700 nm) nanoprobe attracted significant attentions toward in vivo imaging. Regrettably, most of the NIR-II fluorescence probes, especially for inorganic NPs, were hardly excreted from the reticuloendothelial system (RES), yielding the anonymous long-term circulatory safety issue. Results Here, we develop a facile strategy for the fabrication of Nd3+-doped rare-earth core–shell nanoparticles (Nd-RENPs), NaGdF4:5%Nd@NaLuF4, with strong emission in the NIR-II window. What’s more, the Nd-RENPs could be quickly eliminated from the hepatobiliary pathway, reducing the potential risk with the long-term retention in the RES. Further, the Nd-RENPs are successfully utilized for NIR-II in vivo imaging and magnetic resonance imaging (MRI) contrast agents, enabling the precise detection of breast cancer. Conclusions The rationally designed Nd-RENPs nanoprobes manifest rapid-clearance property revealing the potential application toward the noninvasive preoperative imaging of tumor lesions and real-time intra-operative supervision. Graphical abstract

Highly Luminescent CuInS2/ZnS Core/Shell Nanocrystals: Cadmium-Free Quantum Dots for In Vivo Imaging

2009 ◽  
Vol 21 (12) ◽  
pp. 2422-2429 ◽  
Author(s):  
Liang Li ◽  
T. Jean Daou ◽  
Isabelle Texier ◽  
Tran Thi Kim Chi ◽  
Nguyen Quang Liem ◽  
...  
Keyword(s):  
Quantum Dots ◽  
In Vivo Imaging ◽  
Core Shell

Fluorescent proteins for in vivo imaging, where's the biliverdin?

2020 ◽  
Vol 48 (6) ◽  
pp. 2657-2667
Author(s):  
Felipe Montecinos-Franjola ◽  
John Y. Lin ◽  
Erik A. Rodriguez
Keyword(s):  
Hydrogen Peroxide ◽  
In Vivo Imaging ◽  
Near Infrared ◽  
Fluorescent Protein ◽  
Fluorescent Proteins ◽  
Fluorescent Imaging ◽  
Infrared Light ◽  
Red Fluorescent Protein ◽  
Color Palette

Noninvasive fluorescent imaging requires far-red and near-infrared fluorescent proteins for deeper imaging. Near-infrared light penetrates biological tissue with blood vessels due to low absorbance, scattering, and reflection of light and has a greater signal-to-noise due to less autofluorescence. Far-red and near-infrared fluorescent proteins absorb light >600 nm to expand the color palette for imaging multiple biosensors and noninvasive in vivo imaging. The ideal fluorescent proteins are bright, photobleach minimally, express well in the desired cells, do not oligomerize, and generate or incorporate exogenous fluorophores efficiently. Coral-derived red fluorescent proteins require oxygen for fluorophore formation and release two hydrogen peroxide molecules. New fluorescent proteins based on phytochrome and phycobiliproteins use biliverdin IXα as fluorophores, do not require oxygen for maturation to image anaerobic organisms and tumor core, and do not generate hydrogen peroxide. The small Ultra-Red Fluorescent Protein (smURFP) was evolved from a cyanobacterial phycobiliprotein to covalently attach biliverdin as an exogenous fluorophore. The small Ultra-Red Fluorescent Protein is biophysically as bright as the enhanced green fluorescent protein, is exceptionally photostable, used for biosensor development, and visible in living mice. Novel applications of smURFP include in vitro protein diagnostics with attomolar (10−18 M) sensitivity, encapsulation in viral particles, and fluorescent protein nanoparticles. However, the availability of biliverdin limits the fluorescence of biliverdin-attaching fluorescent proteins; hence, extra biliverdin is needed to enhance brightness. New methods for improved biliverdin bioavailability are necessary to develop improved bright far-red and near-infrared fluorescent proteins for noninvasive imaging in vivo.

In vivo imaging of beta-amyloid load in transgenic rodents with [F-18]FDDNP microPET

2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S588-S588
Author(s):  
Vladimir Kepe ◽  
Gregory M Cole ◽  
Jie Liu ◽  
Dorothy G Flood ◽  
Stephen P Trusko ◽  
...  
Keyword(s):  
In Vivo Imaging ◽  
Beta Amyloid ◽  
Amyloid Load
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