scholarly journals Highly efficient single cell arraying by integrating acoustophoretic cell pre-concentration and dielectrophoretic cell trapping

Lab on a Chip ◽  
2015 ◽  
Vol 15 (22) ◽  
pp. 4356-4363 ◽  
Author(s):  
Soo Hyeon Kim ◽  
Maria Antfolk ◽  
Marina Kobayashi ◽  
Shohei Kaneda ◽  
Thomas Laurell ◽  
...  
Keyword(s):  
Single Cell ◽  
High Throughput ◽  
Microfluidic Devices ◽  
Cell Trapping ◽  
Highly Efficient ◽  
Microwell Array ◽  
Novel Approach

We present a novel approach for high throughput single cell arraying by integrating two original microfluidic devices: an acoustofluidic chip and an electroactive microwell array.

High-throughput, deterministic single cell trapping and long-term clonal cell culture in microfluidic devices

Lab on a Chip ◽  
2015 ◽  
Vol 15 (4) ◽  
pp. 1072-1083 ◽  
Author(s):  
Huaying Chen ◽  
Jane Sun ◽  
Ernst Wolvetang ◽  
Justin Cooper-White
Keyword(s):  
High Throughput ◽  
Clonal Growth ◽  
Single Cells ◽  
Microfluidic Devices ◽  
Design Development ◽  
Cell Trapping ◽  
Single Cell Trapping ◽  
Development And Validation

In this paper, the design, development and validation of a novel high throughput microfluidic device enabling both the robust and rapid trapping of 100's to 1000's of single cells and their in situ clonal growth is described.

scholarly journals Hydrodynamic Cell Trapping for High Throughput Single-Cell Applications

Micromachines ◽  
2013 ◽  
Vol 4 (4) ◽  
pp. 414-430 ◽  
Author(s):  
Amin Banaeiyan ◽  
Doryaneh Ahmadpour ◽  
Caroline Adiels ◽  
Mattias Goksör
Keyword(s):  
Single Cell ◽  
High Throughput ◽  
Cell Trapping

High throughput profiling drug response and apoptosis of single polar cells

2020 ◽  
Vol 8 (37) ◽  
pp. 8614-8622
Author(s):  
Xixi Wu ◽  
Shuangshuang Chen ◽  
Qinghua Lu
Keyword(s):  
Single Cell ◽  
High Throughput ◽  
Tumor Heterogeneity ◽  
Drug Response ◽  
Cell Trapping ◽  
Single Cell Trapping

The drug response of single polar cells was evaluated via single cell trapping on anisotropic microwells for tumor heterogeneity.

scholarly journals Efficient analysis of a small number of cancer cells at the single-cell level using an electroactive double-well array

Lab on a Chip ◽  
2016 ◽  
Vol 16 (13) ◽  
pp. 2440-2449 ◽  
Author(s):  
Soo Hyeon Kim ◽  
Teruo Fujii
Keyword(s):  
Single Cell ◽  
Cancer Cells ◽  
Single Cells ◽  
Capture Efficiency ◽  
Single Cell Level ◽  
Cell Capture ◽  
Cell Level ◽  
Cell Trapping ◽  
Highly Efficient ◽  
Single Cell Trapping

The electroactive double well-array consists of trap-wells for highly efficient single-cell trapping using dielectrophoresis (cell capture efficiency of 96 ± 3%) and reaction-wells that confine cell lysates for analysis of intracellular materials from single cells.

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