Inhibitory effects of wild bitter melon leaf extract on Propionibacterium acnes-induced skin inflammation in mice and cytokine production in vitro

2015 ◽  
Vol 6 (8) ◽  
pp. 2550-2560 ◽  
Author(s):  
Wen-Cheng Huang ◽  
Tsung-Hsien Tsai ◽  
Ching-Jang Huang ◽  
You-Yi Li ◽  
Jong-Ho Chyuan ◽  
...  
Keyword(s):  
Leaf Extract ◽  
Cytokine Production ◽  
Propionibacterium Acnes ◽  
Skin Inflammation ◽  
Bitter Melon ◽  
Inhibitory Effects

Propionibacterium acnes is a key pathogen involved in acne inflammation.

scholarly journals Inhibitory effects of Euphorbia supina on Propionibacterium acnes-induced skin inflammation in vitro and in vivo

2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Hyeon-Ji Lim ◽  
Yong-Deok Jeon ◽  
Sa-Haeng Kang ◽  
Min-Kyoung Shin ◽  
Ki-Min Lee ◽  
...  
Keyword(s):  
Propionibacterium Acnes ◽  
Skin Inflammation ◽  
Inhibitory Effects

scholarly journals FT-IR analysis of Sapium ellipticum (Hochst) pax ethanol leaf extract and its inhibitory effects on pancreatic α-amylase and intestinal α-glucosidase activities in vitro

2016 ◽  
Vol 3 (4) ◽  
pp. 343-349 ◽  
Author(s):  
Osasenaga Macdonald Ighodaro ◽  
Oluseyi Adeboye Akinloye ◽  
Regina Ngozi Ugbaja ◽  
Samuel Olatunbosun Omotainse ◽  
Opeyemi Faokunla
Keyword(s):  
Leaf Extract ◽  
Inhibitory Effects ◽  
Ft Ir ◽  
Ir Analysis

scholarly journals Selective Biological Responses of Phagocytes and Lungs to Purified Histones

2017 ◽  
Vol 9 (3) ◽  
pp. 300-317 ◽  
Author(s):  
Fatemeh Fattahi ◽  
Jamison J. Grailer ◽  
Hope Lu ◽  
Rachel S. Dick ◽  
Michella Parlett ◽  
...  
Keyword(s):  
Cytokine Production ◽  
Polymorphonuclear Neutrophils ◽  
Cell Swelling ◽  
Cytokine Release ◽  
Inhibitory Effects ◽  
Lactate Dehydrogenase Release ◽  
Biological Responses ◽  
Proinflammatory Responses ◽  
Mouse Lungs

Histones invoke strong proinflammatory responses in many different organs and cells. We assessed biological responses to purified or recombinant histones, using human and murine phagocytes and mouse lungs. H1 had the strongest ability in vitro to induce cell swelling independent of requirements for toll-like receptors (TLRs) 2 or 4. These responses were also associated with lactate dehydrogenase release. H3 and H2B were the strongest inducers of [Ca2+]i elevations in phagocytes. Cytokine and chemokine release from mouse and human phagocytes was predominately a function of H2A and H2B. Double TLR2 and TLR4 knockout (KO) mice had dramatically reduced cytokine release induced in macrophages exposed to individual histones. In contrast, macrophages from single TLR-KO mice showed few inhibitory effects on cytokine production. Using the NLRP3 inflammasome protocol, release of mature IL-1β was predominantly a feature of H1. Acute lung injury following the airway delivery of histones suggested that H1, H2A, and H2B were linked to alveolar leak of albumin and the buildup of polymorphonuclear neutrophils as well as the release of chemokines and cytokines into bronchoalveolar fluids. These results demonstrate distinct biological roles for individual histones in the context of inflammation biology and the requirement of both TLR2 and TLR4.

scholarly journals UJI EFEKTIVITAS ANTIBAKTERI EKSTRAK DAUN SIRSAK (ANNONA MURICATA LINN.) TERHADAP BAKTERI PROPIONIBACTERIUM ACNES

2019 ◽  
Vol 6 (1) ◽  
pp. 65
Author(s):  
Yurlina Zai ◽  
Agnes Yohana Kristino ◽  
Sri Lestari Ramadhani Nasution ◽  
Oliviti Natali
Keyword(s):  
Leaf Extract ◽  
Propionibacterium Acnes ◽  
Inhibition Zone ◽  
Positive Control ◽  
Negative Control ◽  
Diffusion Method ◽  
Annona Muricata ◽  
Research Model ◽  
Negative Controls

This research aims to determine the effectiveness of the antibacterial soursop leaf extract (Annona muricata L.). The method used is the agar diffusion method. The leaves were extracted by maceration method, using ethanol as a solvent. The soursop leaf extract obtained was then diluted using ethanol 96% at a concentration of 20%, 40%,60%, 80%. Positive control using clindamycin and negative controls using sterile aquadest. The research model used in this study is an experimental research model In Vitro of type. The results showed that soursop leaf extract had antibacterial effectiveness against Propionibacterium acnes with an average inhibition zone diameter of 9,7 mm; 13,7 mm; 15,7 mm; 16,3 mm; positive control (clindamysin) 21,0 mm; and negative control (aquadest) have no value tobe able to inhibit bacterial growth.

Inhibitory effects of CuInS2 and CdTe nanoparticles on macrophage cytokine production and phagocytosis in vitro

2019 ◽  
Vol 127 ◽  
pp. 50-57 ◽  
Author(s):  
Cai-Xia Yao ◽  
Tian-Yang Lin ◽  
Yi-Long Su ◽  
Hui Zou ◽  
Zheng-Yu Yan ◽  
...  
Keyword(s):  
Cytokine Production ◽  
Inhibitory Effects ◽  
Cdte Nanoparticles ◽  
Macrophage Cytokine

scholarly journals Flavones Isolated from Scutellariae radix Suppress Propionibacterium Acnes-Induced Cytokine Production In Vitro and In Vivo

Molecules ◽  
2015 ◽  
Vol 21 (1) ◽  
pp. 15 ◽  
Author(s):  
Po-Jung Tsai ◽  
Wen-Cheng Huang ◽  
Ming-Chi Hsieh ◽  
Ping-Jyun Sung ◽  
Yueh-Hsiung Kuo ◽  
...  
Keyword(s):  
Cytokine Production ◽  
Propionibacterium Acnes ◽  
Scutellariae Radix
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