Facile preparation of hyaluronic acid and transferrin co-modified Fe3O4nanoparticles with inherent biocompatibility for dual-targeting magnetic resonance imaging of tumors in vivo

2015 ◽  
Vol 44 (46) ◽  
pp. 19836-19843 ◽  
Author(s):  
Jinbin Pan ◽  
Shao-Kai Sun ◽  
Yaqiong Wang ◽  
Yan-Yan Fu ◽  
Xuejun Zhang ◽  
...  

A biocompatible and sensitive dual-targeting Fe3O4nanoprobe co-modified with biosafe hyaluronic acid and transferrin was developed for tumor-targeted MR imaging.

Nanoscale ◽  
2019 ◽  
Vol 11 (14) ◽  
pp. 6784-6793 ◽  
Author(s):  
Bo Song ◽  
Wenjing Shi ◽  
Wenbo Shi ◽  
Xiaodan Qin ◽  
Hua Ma ◽  
...  

A novel nanoprobe based on Eu(iii) complex–MnO2 nanosheet nanocomposites has been prepared for dual-modal TGL/MR imaging of GSH in vitro and in vivo.


2021 ◽  
Author(s):  
Bo Song ◽  
Xinyue Zhang ◽  
Xinyi Wen ◽  
Qi Liu ◽  
Hua Ma ◽  
...  

The probes combined luminescence and magnetic resonance (MR) imaging activities have attracted tremendous attention since they can offer both molecular and anatomical information to effectively improve the accuracy of detection....


RSC Advances ◽  
2015 ◽  
Vol 5 (62) ◽  
pp. 50557-50564 ◽  
Author(s):  
Longyun Wu ◽  
ChunYan Yang ◽  
Zhongwen Lv ◽  
FengWen Cui ◽  
Lijun Zhao ◽  
...  

A facile and efficient one-pot solvothermal strategy is described to synthesize Fe3O4 nanoparticles (NPs) modified with sodium citrate, polyvinylpyrrolidone and l-asparagine for in vivo magnetic resonance (MR) imaging of melanoma cells.


2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S692-S692
Author(s):  
Mathias Hoehn ◽  
Uwe Himmelreich ◽  
Ralph Weber ◽  
Pedro Ramos-Cabrer ◽  
Susanne Wegener ◽  
...  

2019 ◽  
Author(s):  
Hamilton Lee ◽  
Jenica Lumata ◽  
Michael A. Luzuriaga ◽  
Candace Benjamin ◽  
Olivia Brohlin ◽  
...  

<div><div><div><p>Many contrast agents for magnetic resonance imaging are based on gadolinium, however side effects limit their use in some patients. Organic radical contrast agents (ORCAs) are potential alternatives, but are reduced rapidly in physiological conditions and have low relaxivities as single molecule contrast agents. Herein, we use a supramolecular strategy where cucurbit[8]uril binds with nanomolar affinities to ORCAs and protects them against biological reductants to create a stable radical in vivo. We further over came the weak contrast by conjugating this complex on the surface of a self-assembled biomacromolecule derived from the tobacco mosaic virus.</p></div></div></div>


Sign in / Sign up

Export Citation Format

Share Document