scholarly journals A plasmonic nanosensor with inverse sensitivity for circulating cell-free DNA quantification

2015 ◽  
Vol 51 (77) ◽  
pp. 14524-14527 ◽  
Author(s):  
Roger M. Pallares ◽  
Say Li Kong ◽  
Tan Hui Ru ◽  
Nguyên T. K. Thanh ◽  
Yi Lu ◽  
...  
Keyword(s):  
Gold Nanorods ◽  
Dna Quantification ◽  
Cell Free Dna ◽  
Free Dna ◽  
Plasmonic Nanosensor ◽  
Circulating Cell Free Dna

A plasmonic nanosensor (using gold nanorods) with inverse sensitivity is presented for circulating cell-free DNA quantification.

304-OR: 5-Hydroxymethylcytosines in Circulating Cell-Free DNA Reveal Diabetic Nephropathy

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 304-OR
Author(s):  
CHANG ZENG ◽  
YING YANG ◽  
ZHOU ZHANG ◽  
CHUAN HE ◽  
WEI ZHANG ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Cell Free Dna ◽  
Free Dna ◽  
Circulating Cell Free Dna

scholarly journals Circulating Cell-Free DNA in Breast Cancer: Searching for Hidden Information towards Precision Medicine

Cancers ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 728
Author(s):  
Maria Panagopoulou ◽  
Manel Esteller ◽  
Ekaterini Chatzaki
Keyword(s):  
Breast Cancer ◽  
Treatment Options ◽  
Treatment Monitoring ◽  
Circulating Biomarkers ◽  
Hidden Information ◽  
Cell Free Dna ◽  
Free Dna ◽  
Current Review ◽  
Circulating Cell Free Dna

Breast cancer (BC) is a leading cause of death between women. Mortality is significantly raised due to drug resistance and metastasis, while personalized treatment options are obstructed by the limitations of conventional biopsy follow-up. Lately, research is focusing on circulating biomarkers as minimally invasive choices for diagnosis, prognosis and treatment monitoring. Circulating cell-free DNA (ccfDNA) is a promising liquid biopsy biomaterial of great potential as it is thought to mirror the tumor’s lifespan; however, its clinical exploitation is burdened mainly by gaps in knowledge of its biology and specific characteristics. The current review aims to gather latest findings about the nature of ccfDNA and its multiple molecular and biological characteristics in breast cancer, covering basic and translational research and giving insights about its validity in a clinical setting.

scholarly journals The biomolecule corona of lipid nanoparticles contains circulating cell-free DNA

2020 ◽  
Vol 5 (11) ◽  
pp. 1476-1486
Author(s):  
Lois Gardner ◽  
Jessica Warrington ◽  
Jane Rogan ◽  
Dominic G. Rothwell ◽  
Ged Brady ◽  
...  
Keyword(s):  
Human Plasma ◽  
Lipid Nanoparticles ◽  
Cell Free Dna ◽  
Free Dna ◽  
Circulating Cell Free Dna

The biomolecule corona spontaneously adsorbed onto lipid-based nanoparticles (NPs), upon incubation with human plasma, contains circulating cell-free DNA (cfDNA).

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