Effect of the tip length of multi-branched AuNFs on the detection performance of immunochromatographic assays

2016 ◽  
Vol 8 (16) ◽  
pp. 3316-3324 ◽  
Author(s):  
Peng Xu ◽  
Juan Li ◽  
Xiaolin Huang ◽  
Hong Duan ◽  
Yanwei Ji ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Detection Performance ◽  
Immunochromatographic Assay ◽  
Optical Intensity ◽  
Spherical Gold Nanoparticles ◽  
Low Sensitivity

The traditional immunochromatographic assay (ICA) using conventional spherical gold nanoparticles (AuNSs, 30–40 nm) as labeled probes usually suffers from low sensitivity because of insufficient probe optical intensity.

Effect of different-sized spherical gold nanoparticles grown layer by layer on the sensitivity of an immunochromatographic assay

RSC Advances ◽  
2016 ◽  
Vol 6 (31) ◽  
pp. 26178-26185 ◽  
Author(s):  
Juan Li ◽  
Hong Duan ◽  
Peng Xu ◽  
Xiaolin Huang ◽  
Yonghua Xiong
Keyword(s):  
Gold Nanoparticles ◽  
Immunochromatographic Assay ◽  
Layer By Layer ◽  
Grown Layer ◽  
Spherical Gold Nanoparticles

Effect of different-sized spherical gold nanoparticles grown layer by layer on the sensitivity of immunochromatographic assay.

scholarly journals Varied-shaped gold nanoparticles with nanogram killing efficiency as potential antimicrobial surface coatings for the medical devices

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ewelina Piktel ◽  
Łukasz Suprewicz ◽  
Joanna Depciuch ◽  
Sylwia Chmielewska ◽  
Karol Skłodowski ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Medical Devices ◽  
Multidrug Resistant ◽  
Resistance Mechanisms ◽  
Antimicrobial Spectrum ◽  
Antimicrobial Coatings ◽  
Low Toxicity ◽  
Spherical Gold Nanoparticles ◽  
Cost Efficient ◽  
Bactericidal Efficiency

AbstractMedical device-associated infections are a serious medical threat, particularly for patients with impaired mobility and/or advanced age. Despite a variety of antimicrobial coatings for medical devices being explored to date, only a limited number have been introduced for clinical use. Research into new bactericidal agents with the ability to eradicate pathogens, limit biofilm formation, and exhibit satisfactory biocompatibility, is therefore necessary and urgent. In this study, a series of varied-morphology gold nanoparticles in shapes of rods, peanuts, stars and spherical-like, porous ones with potent antibacterial activity were synthesized and thoroughly tested against spectrum of Candida albicans, Pseudomonas aeruginosa, Staphylococcus aureus clinical strains, as well as spectrum of uropathogenic Escherichia coli isolates. The optimization of gold nanoparticles synthesis allowed to develop nanomaterials, which are proved to be significantly more potent against tested microbes compared with the gold nanoformulations reported to date. Notably, their antimicrobial spectrum includes strains with different drug resistance mechanisms. Facile and cost-efficient synthesis of gold nanoparticles, remarkable bactericidal efficiency at nanogram doses, and low toxicity, underline their potential for development as a new coatings, as indicated by the example of urological catheters. The presented research fills a gap in microbial studies of non-spherical gold nanoparticles for the development of antimicrobial coatings targeting multidrug-resistant pathogens responsible for device-associated nosocomial infections.

Endocytosis and exocytosis processes of gold nanoparticle with erythrocyte ghosts

MRS Advances ◽  
2020 ◽  
Vol 5 (42) ◽  
pp. 2169-2172 ◽  
Author(s):  
Víctor Gómez Flores
Keyword(s):  
Gold Nanoparticles ◽  
Surface Modification ◽  
Sem Analysis ◽  
Erythrocyte Ghosts ◽  
Simple Diffusion ◽  
Membrane Interaction ◽  
Vis Spectroscopy ◽  
Plasmatic Membrane ◽  
Result Show ◽  
Spherical Gold Nanoparticles

AbstractThe interaction of spherical gold nanoparticles (AuNPs) of 20nm elaborated by Turkevich method with the erythrocytes ghosts (7-8 μm) cell membrane was evaluated. The AuNPs-Membrane interaction was determined using confocal microscope, Uv-Vis spectroscopy and SEM analysis. The result show that nanoparticles larger than 20nm are adhered to the erythrocyte ghost membrane due their size and surface modification. Smaller AuNPs enter onto the cell by simple diffusion through the plasmatic membrane voids, these data may favor the best design and application in the treatments applied in biomedicine.

Reverse Size Dependences of the Cellular Uptake of Triangular and Spherical Gold Nanoparticles

Langmuir ◽  
2016 ◽  
Vol 32 (47) ◽  
pp. 12559-12567 ◽  
Author(s):  
Katsuyuki Nambara ◽  
Kenichi Niikura ◽  
Hideyuki Mitomo ◽  
Takafumi Ninomiya ◽  
Chie Takeuchi ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Cellular Uptake ◽  
Spherical Gold Nanoparticles
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