Multiple detection of single nucleotide polymorphism by microarray-based resonance light scattering assay with enlarged gold nanoparticle probes

The Analyst ◽  
2016 ◽  
Vol 141 (5) ◽  
pp. 1772-1778 ◽  
Author(s):  
Jiaxue Gao ◽  
Lan Ma ◽  
Zhen Lei ◽  
Zhenxin Wang
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Light Scattering ◽  
Gold Nanoparticle ◽  
High Sensitivity ◽  
Resonance Light Scattering ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide ◽  
Multiplexed Detection ◽  
Nanoparticle Probes ◽  
Multiple Detection

A gold nanoparticle enlargement assisted DNA microarray-based RLS assay has been developed for multiplexed detection of single nucleotide polymorphism with high sensitivity.

Gold nanoparticle-based colorimetric assay of single-nucleotide polymorphism of triplex DNA

2010 ◽  
Vol 25 (9) ◽  
pp. 2135-2139 ◽  
Author(s):  
Xiaoli Zhu ◽  
Yuexing Liu ◽  
Jinghua Yang ◽  
Zhiqiang Liang ◽  
Genxi Li
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Gold Nanoparticle ◽  
Colorimetric Assay ◽  
Triplex Dna ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide

scholarly journals Simultaneous multiple single nucleotide polymorphism detection based on click chemistry combined with DNA-encoded probes

2018 ◽  
Vol 9 (13) ◽  
pp. 3335-3340 ◽  
Author(s):  
Qian-Yu Zhou ◽  
Fang Yuan ◽  
Xiao-Hui Zhang ◽  
Ying-Lin Zhou ◽  
Xin-Xiang Zhang
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Click Reaction ◽  
High Sensitivity ◽  
Dna Ligase ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide Polymorphism Detection ◽  
Single Nucleotide ◽  
Polymorphism Detection ◽  
Novel Strategy ◽  
Dna Template

A novel strategy utilizing a DNA template-directed CuAAC click reaction to mimic a ligation reaction based on DNA ligase was successfully established for multiple SNP detection with high sensitivity and specificity.

Detection of single nucleotide polymorphism by measuring extension kinetics with T7 exonuclease mediated isothermal amplification

The Analyst ◽  
2018 ◽  
Vol 143 (1) ◽  
pp. 116-122 ◽  
Author(s):  
Miao Cui ◽  
Xianjin Xiao ◽  
Meiping Zhao ◽  
Bo Zheng
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Sensitivity And Specificity ◽  
Room Temperature ◽  
High Sensitivity ◽  
Isothermal Amplification ◽  
Nucleotide Polymorphism ◽  
Single Nucleotide ◽  
T7 Exonuclease

Kinetics based detection of single nucleotide polymorphism at room temperature with high sensitivity and specificity.

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