A water soluble initiator prepared through host–guest chemical interaction for microfabrication of 3D hydrogels via two-photon polymerization

2014 ◽  
Vol 2 (27) ◽  
pp. 4318-4323 ◽  
Author(s):  
Jinfeng Xing ◽  
Jinhao Liu ◽  
Tingbin Zhang ◽  
Ling Zhang ◽  
Meiling Zheng ◽  
...  
Keyword(s):  
Organic Solvents ◽  
Laser Power ◽  
Chemical Interaction ◽  
Water Soluble ◽  
Two Photon ◽  
Highly Efficient ◽  
Two Photon Polymerization

A highly efficient water soluble initiator was prepared through host–guest chemical interaction combining a hydrophobic TPP initiator and hydrophilic cyclodextrins. 3D hydrogels without the residue of organic solvents were successfully achieved via TPP using low laser power.

scholarly journals Two-photon polymerization nanolithography technology for fabrication of stimulus-responsive micro/nano-structures for biomedical applications

2020 ◽  
Vol 9 (1) ◽  
pp. 1118-1136
Author(s):  
Zhenjia Huang ◽  
Gary Chi-Pong Tsui ◽  
Yu Deng ◽  
Chak-Yin Tang
Keyword(s):  
Biomedical Applications ◽  
Three Dimensional ◽  
Water Soluble ◽  
Fabrication Technology ◽  
Nano Fabrication ◽  
Two Photon ◽  
Nano Structures ◽  
Wide Range ◽  
Stimulus Responsive ◽  
Two Photon Polymerization

AbstractMicro/nano-fabrication technology via two-photon polymerization (TPP) nanolithography is a powerful and useful manufacturing tool that is capable of generating two dimensional (2D) to three dimensional (3D) arbitrary micro/nano-structures of various materials with a high spatial resolution. This technology has received tremendous interest in cell and tissue engineering and medical microdevices because of its remarkable fabrication capability for sophisticated structures from macro- to nano-scale, which are difficult to be achieved by traditional methods with limited microarchitecture controllability. To fabricate precisely designed 3D micro/nano-structures for biomedical applications via TPP nanolithography, the use of photoinitiators (PIs) and photoresists needs to be considered comprehensively and systematically. In this review, widely used commercially available PIs are first discussed, followed by elucidating synthesis strategies of water-soluble initiators for biomedical applications. In addition to the conventional photoresists, the distinctive properties of customized stimulus-responsive photoresists are discussed. Finally, current limitations and challenges in the material and fabrication aspects and an outlook for future prospects of TPP for biomedical applications based on different biocompatible photosensitive composites are discussed comprehensively. In all, this review provides a basic understanding of TPP technology and important roles of PIs and photoresists for fabricating high-precision stimulus-responsive micro/nano-structures for a wide range of biomedical applications.

Acoustic Field-Assisted Two-Photon Polymerization Process

2021 ◽  
Vol 143 (10) ◽  
Author(s):  
Ketki M. Lichade ◽  
Yayue Pan
Keyword(s):  
Polymer Composite ◽  
Acoustic Field ◽  
Laser Power ◽  
Liquid Droplet ◽  
Three Dimensional ◽  
Polymerization Process ◽  
Photothermal Effect ◽  
Full Potential ◽  
Two Photon ◽  
Two Photon Polymerization

Abstract This study successfully integrates acoustic patterning with the Two-Photon Polymerization (TPP) process for printing nanoparticle–polymer composite microstructures with spatially varied nanoparticle compositions. Currently, the TPP process is gaining increasing attention within the engineering community for the direct manufacturing of complex three-dimensional (3D) microstructures. Yet the full potential of TPP manufactured microstructures is limited by the materials used. This study aims to create and demonstrate a novel acoustic field-assisted TPP (A-TPP) process, which can instantaneously pattern and assemble nanoparticles in a liquid droplet, and fabricate anisotropic nanoparticle–polymer composites with spatially controlled particle–polymer material compositions. It was found that the biggest challenge in integrating acoustic particle patterning with the TPP process is that nanoparticles move upon laser irradiation due to the photothermal effect, and hence, the acoustic assembly is distorted during the photopolymerization process. To cure acoustic assembly of nanoparticles in the resin through TPP with the desired nanoparticle patterns, the laser power needs to be carefully tuned so that it is adequate for curing while low enough to prevent the photothermal effect. To address this challenge, this study investigated the threshold laser power for polymerization of TPP resin (Pthr) and photothermal instability of the nanoparticle (Pthp). Patterned nanoparticle–polymer composite microstructures were fabricated using the novel A-TPP process. Experimental results validated the feasibility of the developed acoustic field-assisted TPP process on printing anisotropic composites with spatially controlled material compositions.

A Straightforward Synthesis and Structure–Activity Relationship of Highly Efficient Initiators for Two-Photon Polymerization

2013 ◽  
Vol 46 (2) ◽  
pp. 352-361 ◽  
Author(s):  
Zhiquan Li ◽  
Niklas Pucher ◽  
Klaus Cicha ◽  
Jan Torgersen ◽  
Samuel C. Ligon ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Two Photon ◽  
Highly Efficient ◽  
Structure Activity ◽  
Relationship Of ◽  
Two Photon Polymerization

3D hydrogels with high resolution fabricated by two-photon polymerization with sensitive water soluble initiators

2015 ◽  
Vol 3 (43) ◽  
pp. 8486-8491 ◽  
Author(s):  
Jinfeng Xing ◽  
Ling Liu ◽  
Xiaoyan Song ◽  
Yuanyuan Zhao ◽  
Ling Zhang ◽  
...  
Keyword(s):  
High Resolution ◽  
Spatial Resolution ◽  
Biomedical Applications ◽  
Water Soluble ◽  
Two Photon ◽  
Two Photon Polymerization

Hydrogels with precise 3D configuration are crucial for biomedical applications, which demand for the improvement of the spatial resolution on both the microscopic and the nanometric scale.

Two-photon polymerization of polyethylene glycol diacrylate scaffolds with riboflavin and triethanolamine used as a water-soluble photoinitiator

2013 ◽  
Vol 8 (6) ◽  
pp. 725-738 ◽  
Author(s):  
Alexander K Nguyen ◽  
Shaun D Gittard ◽  
Anastasia Koroleva ◽  
Sabrina Schlie ◽  
Arune Gaidukeviciute ◽  
...  
Keyword(s):  
Polyethylene Glycol ◽  
Water Soluble ◽  
Polyethylene Glycol Diacrylate ◽  
Glycol Diacrylate ◽  
Two Photon ◽  
Two Photon Polymerization

Water-Soluble, Donor-Acceptor Biphenyl Derivatives in the 2-(o-Nitrophenyl)propyl Series: Highly Efficient Two-Photon Uncaging of the Neurotransmitter γ-Aminobutyric Acid at λ=800 nm

2012 ◽  
Vol 124 (8) ◽  
pp. 1876-1879 ◽  
Author(s):  
Loïc Donato ◽  
Alexandre Mourot ◽  
Christopher M. Davenport ◽  
Cyril Herbivo ◽  
David Warther ◽  
...  
Keyword(s):  
Water Soluble ◽  
Aminobutyric Acid ◽  
Two Photon ◽  
Highly Efficient ◽  
Donor Acceptor

Water-soluble photopolymerizable chitosan hydrogels for biofabrication via two-photon polymerization

2015 ◽  
Vol 18 ◽  
pp. 186-195 ◽  
Author(s):  
Olga Kufelt ◽  
Ayman El-Tamer ◽  
Camilla Sehring ◽  
Marita Meißner ◽  
Sabrina Schlie-Wolter ◽  
...  
Keyword(s):  
Water Soluble ◽  
Two Photon ◽  
Chitosan Hydrogels ◽  
Two Photon Polymerization
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