3D hydrogels with high resolution fabricated by two-photon polymerization with sensitive water soluble initiators

2015 ◽  
Vol 3 (43) ◽  
pp. 8486-8491 ◽  
Author(s):  
Jinfeng Xing ◽  
Ling Liu ◽  
Xiaoyan Song ◽  
Yuanyuan Zhao ◽  
Ling Zhang ◽  
...  
Keyword(s):  
High Resolution ◽  
Spatial Resolution ◽  
Biomedical Applications ◽  
Water Soluble ◽  
Two Photon ◽  
Two Photon Polymerization

Hydrogels with precise 3D configuration are crucial for biomedical applications, which demand for the improvement of the spatial resolution on both the microscopic and the nanometric scale.

scholarly journals Two-photon polymerization nanolithography technology for fabrication of stimulus-responsive micro/nano-structures for biomedical applications

2020 ◽  
Vol 9 (1) ◽  
pp. 1118-1136
Author(s):  
Zhenjia Huang ◽  
Gary Chi-Pong Tsui ◽  
Yu Deng ◽  
Chak-Yin Tang
Keyword(s):  
Biomedical Applications ◽  
Three Dimensional ◽  
Water Soluble ◽  
Fabrication Technology ◽  
Nano Fabrication ◽  
Two Photon ◽  
Nano Structures ◽  
Wide Range ◽  
Stimulus Responsive ◽  
Two Photon Polymerization

AbstractMicro/nano-fabrication technology via two-photon polymerization (TPP) nanolithography is a powerful and useful manufacturing tool that is capable of generating two dimensional (2D) to three dimensional (3D) arbitrary micro/nano-structures of various materials with a high spatial resolution. This technology has received tremendous interest in cell and tissue engineering and medical microdevices because of its remarkable fabrication capability for sophisticated structures from macro- to nano-scale, which are difficult to be achieved by traditional methods with limited microarchitecture controllability. To fabricate precisely designed 3D micro/nano-structures for biomedical applications via TPP nanolithography, the use of photoinitiators (PIs) and photoresists needs to be considered comprehensively and systematically. In this review, widely used commercially available PIs are first discussed, followed by elucidating synthesis strategies of water-soluble initiators for biomedical applications. In addition to the conventional photoresists, the distinctive properties of customized stimulus-responsive photoresists are discussed. Finally, current limitations and challenges in the material and fabrication aspects and an outlook for future prospects of TPP for biomedical applications based on different biocompatible photosensitive composites are discussed comprehensively. In all, this review provides a basic understanding of TPP technology and important roles of PIs and photoresists for fabricating high-precision stimulus-responsive micro/nano-structures for a wide range of biomedical applications.

Photonic and Biomedical Applications of the Two-Photon Polymerization Technique

2011 ◽  
pp. 257-297
Author(s):  
Aleksandr Ovsianikov ◽  
Maria Farsari ◽  
Boris N. Chichkov
Keyword(s):  
Biomedical Applications ◽  
Two Photon ◽  
Two Photon Polymerization

A water soluble initiator prepared through host–guest chemical interaction for microfabrication of 3D hydrogels via two-photon polymerization

2014 ◽  
Vol 2 (27) ◽  
pp. 4318-4323 ◽  
Author(s):  
Jinfeng Xing ◽  
Jinhao Liu ◽  
Tingbin Zhang ◽  
Ling Zhang ◽  
Meiling Zheng ◽  
...  
Keyword(s):  
Organic Solvents ◽  
Laser Power ◽  
Chemical Interaction ◽  
Water Soluble ◽  
Two Photon ◽  
Highly Efficient ◽  
Two Photon Polymerization

A highly efficient water soluble initiator was prepared through host–guest chemical interaction combining a hydrophobic TPP initiator and hydrophilic cyclodextrins. 3D hydrogels without the residue of organic solvents were successfully achieved via TPP using low laser power.

Two-photon polymerization of polyethylene glycol diacrylate scaffolds with riboflavin and triethanolamine used as a water-soluble photoinitiator

2013 ◽  
Vol 8 (6) ◽  
pp. 725-738 ◽  
Author(s):  
Alexander K Nguyen ◽  
Shaun D Gittard ◽  
Anastasia Koroleva ◽  
Sabrina Schlie ◽  
Arune Gaidukeviciute ◽  
...  
Keyword(s):  
Polyethylene Glycol ◽  
Water Soluble ◽  
Polyethylene Glycol Diacrylate ◽  
Glycol Diacrylate ◽  
Two Photon ◽  
Two Photon Polymerization

Water-soluble photopolymerizable chitosan hydrogels for biofabrication via two-photon polymerization

2015 ◽  
Vol 18 ◽  
pp. 186-195 ◽  
Author(s):  
Olga Kufelt ◽  
Ayman El-Tamer ◽  
Camilla Sehring ◽  
Marita Meißner ◽  
Sabrina Schlie-Wolter ◽  
...  
Keyword(s):  
Water Soluble ◽  
Two Photon ◽  
Chitosan Hydrogels ◽  
Two Photon Polymerization
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