Polysaccharide from garlic straw: extraction, structural data, biological properties and application to beef meat preservation

RSC Advances ◽  
2015 ◽  
Vol 5 (9) ◽  
pp. 6728-6741 ◽  
Author(s):  
Fatma Kallel ◽  
Dorra Driss ◽  
Fatma Bouaziz ◽  
Lilia Belghith ◽  
Soumaya Zouari-Ellouzi ◽  
...  
Keyword(s):  
Allium Sativum ◽  
Structural Data ◽  
Biological Properties ◽  
Hot Water ◽  
Beef Meat ◽  
Meat Preservation

A novel polysaccharide (GSP) was isolated from garlic straw (Allium sativumL.) by hot water technique.

Structural data and biological properties of almond gum oligosaccharide: Application to beef meat preservation

2015 ◽  
Vol 72 ◽  
pp. 472-479 ◽  
Author(s):  
Fatma Bouaziz ◽  
Claire Boisset Helbert ◽  
Molka Ben Romdhane ◽  
Mohamed Koubaa ◽  
Fatma Bhiri ◽  
...  
Keyword(s):  
Structural Data ◽  
Biological Properties ◽  
Beef Meat ◽  
Meat Preservation

scholarly journals Hovenia dulcis Thumberg: Phytochemistry, Pharmacology, Toxicology and Regulatory Framework for Its Use in the European Union

Molecules ◽  
2021 ◽  
Vol 26 (4) ◽  
pp. 903
Author(s):  
Gianluca Sferrazza ◽  
Gloria Brusotti ◽  
Manuela Zonfrillo ◽  
Caterina Temporini ◽  
Sara Tengattini ◽  
...  
Keyword(s):  
European Union ◽  
Herbal Remedy ◽  
Biological Activities ◽  
Water Extract ◽  
Biological Properties ◽  
Hot Water ◽  
Special Focus ◽  
Root Bark ◽  
The European Union ◽  
Hovenia Dulcis

Hovenia dulcis Thunberg is an herbal plant, belonging to the Rhamnaceae family, widespread in west Asia, USA, Australia and New Zealand, but still almost unknown in Western countries. H. dulcis has been described to possess several pharmacological properties, such as antidiabetic, anticancer, antioxidant, anti-inflammatory and hepatoprotective, especially in the hangover treatment, validating its use as an herbal remedy in the Chinese Traditional Medicine. These biological properties are related to a variety of secondary metabolites synthesized by the different plant parts. Root, bark and leaves are rich of dammarane-type triterpene saponins; dihydrokaempferol, quercetin, 3,3′,5′,5,7-pentahydroflavone and dihydromyricetin are flavonoids isolated from the seeds; fruits contain mainly dihydroflavonols, such as dihydromyricetin (or ampelopsin) and hovenodulinol, and flavonols such as myricetin and gallocatechin; alkaloids were found in root, barks (frangulanin) and seeds (perlolyrin), and organic acids (vanillic and ferulic) in hot water extract from seeds. Finally, peduncles have plenty of polysaccharides which justify the use as a food supplement. The aim of this work is to review the whole scientific production, with special focus on the last decade, in order to update phytochemistry, biological activities, nutritional properties, toxicological aspect and regulatory classification of H. dulcis extracts for its use in the European Union.

scholarly journals Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review

Nutrients ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 872 ◽  
Author(s):  
Gaber El-Saber Batiha ◽  
Amany Magdy Beshbishy ◽  
Lamiaa G. Wasef ◽  
Yaser H. A. Elewa ◽  
Ahmed A. Al-Sagan ◽  
...  
Keyword(s):  
Allium Sativum ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Biological Properties ◽  
Herbaceous Plant ◽  
Anticancer Activities ◽  
Active Constituent ◽  
Pharmacological Activities ◽  
Traditional Medicines ◽  
Traditional Remedy

Medicinal plants have been used from ancient times for human healthcare as in the form of traditional medicines, spices, and other food components. Garlic (Allium sativum L.) is an aromatic herbaceous plant that is consumed worldwide as food and traditional remedy for various diseases. It has been reported to possess several biological properties including anticarcinogenic, antioxidant, antidiabetic, renoprotective, anti-atherosclerotic, antibacterial, antifungal, and antihypertensive activities in traditional medicines. A. sativum is rich in several sulfur-containing phytoconstituents such as alliin, allicin, ajoenes, vinyldithiins, and flavonoids such as quercetin. Extracts and isolated compounds of A. sativum have been evaluated for various biological activities including antibacterial, antiviral, antifungal, antiprotozoal, antioxidant, anti-inflammatory, and anticancer activities among others. This review examines the phytochemical composition, pharmacokinetics, and pharmacological activities of A. sativum extracts as well as its main active constituent, allicin.

Essential oil from pistachio by-product: potential biological properties and natural preservative effect in ground beef meat storage

2020 ◽  
Vol 14 (6) ◽  
pp. 3020-3030 ◽  
Author(s):  
Fatma Krichen ◽  
Mariem Hamed ◽  
Wafa Karoud ◽  
Hajer Bougatef ◽  
Assaad Sila ◽  
...  
Keyword(s):  
Essential Oil ◽  
Ground Beef ◽  
Biological Properties ◽  
Natural Preservative ◽  
Beef Meat

scholarly journals Deep Eutectic Solvent-Assisted Extraction, Partially Structural Characterization, and Bioactivities of Acidic Polysaccharides from Lotus Leaves

Foods ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 2330
Author(s):  
Ding-Tao Wu ◽  
Kang-Lin Feng ◽  
Ling Huang ◽  
Ren-You Gan ◽  
Yi-Chen Hu ◽  
...  
Keyword(s):  
Functional Food ◽  
Food Industry ◽  
Deep Eutectic Solvent ◽  
Biological Properties ◽  
Hot Water ◽  
Extraction Temperature ◽  
Assisted Extraction ◽  
Acidic Polysaccharides ◽  
Lotus Leaves

Lotus leaves are often discarded as byproducts in the lotus industry. Polysaccharides are regarded as one of the essentially bioactive components in lotus leaves. Therefore, in order to promote the application of lotus leaves in the functional food industry, the deep eutectic solvent (DES) assisted extraction of polysaccharides from lotus leaves (LLPs) was optimized, and structural and biological properties of LLPs extracted by DES and hot water were further investigated. At the optimal extraction conditions (water content of 61.0% in DES, extraction temperature of 92 °C, liquid-solid ratio of 31.0 mL/g and extraction time of 126 min), the maximum extraction yield (5.38%) was obtained. Furthermore, LLP-D extracted by DES and LLP-W extracted by hot water possessed the same sugar residues, such as 1,4-α-D-GalAp, 1,4-α-D-GalAMep, 1,3,6-β-D-Galp, 1,4-β-D-Galp, 1,5-α-L-Araf, and 1,2-α-L-Rhap, suggesting the presence of homogalacturonan (HG), rhamnogalacturonan I and arabinogalactan in both LLP-W and LLP-D. Notably, LLP-D was much richer in HG fraction than that of LLP-W, suggesting that the DES could assist to specifically extract HG from lotus leaves. Additionally, the lower molecular weight and higher content of uronic acids were observed in LLP-D, which might contribute to its much stronger in vitro antioxidant, hypoglycemic, and immunomodulatory effects. These findings suggest that the optimized DES assisted extraction method can be a potential approach for specific extraction of acidic polysaccharides with good bioactivities from lotus leaves for applications in the functional food industry.

scholarly journals The Effect of Pectinase-Assisted Extraction on the Physicochemical and Biological Properties of Polysaccharides from Aster scaber

2018 ◽  
Vol 19 (9) ◽  
pp. 2839 ◽  
Author(s):  
Young-Ran Song ◽  
Su-Kyung Sung ◽  
Eun-Ju Shin ◽  
Chang-Won Cho ◽  
Chun-Ji Han ◽  
...  
Keyword(s):  
Lymphocyte Proliferation ◽  
Nk Cell ◽  
Biological Effects ◽  
Cell Activity ◽  
Biological Properties ◽  
Hot Water ◽  
Perennial Herb ◽  
Composition Analysis ◽  
Immunostimulatory Activity ◽  
Raw264.7 Macrophages

The edible and medicinal perennial herb Aster scaber is known to have anticancer, antioxidant, and immunomodulatory properties. However, the biological effects of its polysaccharides are not well understood. Here, we aimed to extract novel polysaccharides with enhanced biological properties from Aster scaber using enzyme-assisted methods. Amylase, cellulase, and pectinase were used to extract enzyme-assisted polysaccharide (ASEP)-A, ASEP-C, and ASEP-P, respectively. The yields, physicochemical properties, and immunostimulatory activities of the polysaccharides were investigated and compared with those of hot water extracted polysaccharide (ASWP). The highest yield (3.8%) was achieved for ASEP-P extracted using pectinase digestion. Fourier-transform infrared spectroscopy (FT-IR) and chemical composition analysis revealed that ASWP and three ASEPs were typical acidic heteropolysaccharides, mainly comprising rhamnose, arabinose, galactose, glucose, and galacturonic acid. Immunostimulatory activity assays on RAW264.7 macrophages showed ASEP-P to have the greatest immunostimulatory potential in terms of nitric oxide (NO) and cytokine productions and phagocytic activity. ASEP-P administration improved immune-enhancing effects in normal mice by improving the spleen index and splenic lymphocyte proliferation, and in immunosuppressed mice by modulating lymphocyte proliferation, natural killer (NK) cell activity, and leukocyte counts. The ASEP-P derived from pectinase hydrolysate of Aster scaber demonstrated efficacious immunostimulatory properties and has potential applications as an immune stimulator.

scholarly journals Diarrhea Infections in North-Eastern Ukraine: Evolution of Epidemic Process

2020 ◽  
Vol 19 (3) ◽  
pp. 420-426
Author(s):  
Nina Malysh ◽  
Mycola Chemych ◽  
Viktoriya Zadorozhna ◽  
Alla Podavalenko ◽  
Svitlana Birukova
Keyword(s):  
Typhoid Fever ◽  
Water Supply ◽  
Medical Science ◽  
Biological Properties ◽  
Pathogen Transmission ◽  
Hot Water ◽  
Epidemiological Surveillance ◽  
Pathogenic Potential ◽  
Epidemic Process ◽  
North Eastern

Background: The significance of some infection sources, pathways of pathogen transmission and etiological structure of diarrhea infections (DI) have changed. Many issues of DI epidemiology are still insufficiently studied, which prevents the organisation of quality epidemiological surveillance and diseases control. Objectives: To study the DI epidemic situation (ES) in North- Eastern Ukraine and to identify the factors that determines the characteristics of epidemic process (EP). Material and Methods: The reports of Ministry of Health of Ukraine (1960- 2018) and Head Statistics Administration of Sumy Oblast (2001-2018) have been used. The biological properties of 40 strains of K. pneumoniae, 50 - S. aureus, 40 - E. cloacae recovered from the feces of patients with DI have been studied Results: It has been found that the EP of DI is characterized by a sharp decrease in the incidence of typhoid fever and shigellosis, increase in the incidence of salmonellosis and dominance of DI caused by other specified or unspecified pathogens (SDI and UDI) in the nosological structure (p<0.05). The incidence of DI caused by Klebsiella, Staphylococus, Enterobacters exceeds the incidence of salmonellosis, shigellosis, typhoid fever (p<0.05). Opportunistic pathogens (OP), which are pathogens of DI have antilysozyme activity and adhesion ability, which proves their pathogenic potential. The demographics indirectly affect the incidence of DI. Access to water supply, sewerage, hot water supply is correlates with the incidence of DI. Conclusion: The system of epidemiological surveillance over DI in Ukraine needs improvement by optimisation its information and analytical subsystems aimed at objective epidemiological diagnostics and ES forecasting. Bangladesh Journal of Medical Science Vol.19(3) 2020 p.420-426

scholarly journals Anti-bacterial and Anti-fungal Properties of Garlic Extract (Allium sativum): A Review

2019 ◽  
pp. 1-5 ◽  
Author(s):  
Bulti Kumera Fufa
Keyword(s):  
Allium Sativum ◽  
Fungal Infections ◽  
Cardiovascular Effects ◽  
Biological Properties ◽  
Garlic Extract ◽  
Biologically Active ◽  
Zone Of Inhibition ◽  
Active Components ◽  
Microbial Potential ◽  
Anti Fungal

Garlic (Allium sativum) contains various biologically active components that play a significant role in the treatment of bacterial and fungal infections. It contains sulfur compounds like allicin, ajoene, allylmethyltrisulfide, diallyltrisulfide, diallyldisulphide and others which exhibit various biological properties like antimicrobial, anticancer, antioxidant, immunomodulatory, anti-inflammatory, hypoglycemic and cardiovascular effects. The objective of the current review was to relate various literatures and assess the anti-microbial potential of garlic extract. The antimicrobial potency of garlic can be maximised by increasing the concentration of the extract. Garlic extract of 100% concentration showed a maximum zone of inhibition against both gram-positive and gram-negative bacteria.

scholarly journals Complexes of Fabs with a mimetic of the HIV-1 gp41 trimeric coiled-coil.

2014 ◽  
Vol 70 (a1) ◽  
pp. C1809-C1809
Author(s):  
Mi Li ◽  
Elena Gustchina ◽  
Alla Gustchina ◽  
Marius Clore ◽  
Alexander Wlodawer
Keyword(s):  
Crystal Structures ◽  
Neutralizing Antibodies ◽  
Body Movement ◽  
Coiled Coil ◽  
Structural Data ◽  
Biological Properties ◽  
Heptad Repeat ◽  
X Ray Crystallography ◽  
Subtype B ◽  
Hiv 1

A series of mini-antibodies (monovalent and bivalent Fabs) targeting the conserved internal trimeric coiled-coil of the N-heptad repeat (N-HR) of HIV-1 gp41 has been previously constructed and reported. Crystal structures of two closely related monovalent Fabs, one (Fab 8066) broadly neutralizing across a wide panel of HIV-1 subtype B and C viruses, and the other (Fab 8062) non-neutralizing, representing the extremes of this series, were previously solved as complexes with 5-Helix, a gp41 pre-hairpin intermediate mimetic. Binding of these Fabs to covalently stabilized chimeric trimers of N-peptides of HIV-1 gp41 (named (CCIZN36)3 or 3-H) has now been investigated using X-ray crystallography, cryo-electron microscopy, and a variety of biophysical methods. Crystal structures of the complexes between 3-H and Fab 8066 and Fab 8062 were determined at 2.8 and 3.0 Å resolution, respectively. Although the structures of the complexes with the neutralizing Fab 8066 and its non-neutralizing counterpart Fab 8062 were generally similar, small differences between them could be correlated with the biological properties of these antibodies. The conformations of the corresponding CDRs of each antibody in the complexes with 3-H and 5-Helix are very similar. The adaptation to a different target upon complex formation is predominantly achieved by changes in the structure of the trimer of N-HR helices, as well as by adjustment of the orientation of the Fab molecule relative to the N-HR in the complex, via rigid-body movement. The structural data presented here indicate that binding of three Fabs 8062 with high affinity requires more significant changes in the structure of the N-HR trimer compared to binding of Fab 8066. A comparative analysis of the structures of Fabs complexed to different gp41 intermediate mimetics allows further evaluation of biological relevance for generation of neutralizing antibodies, as well as provides novel structural insights into immunogen design.

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