scholarly journals Hovenia dulcis Thumberg: Phytochemistry, Pharmacology, Toxicology and Regulatory Framework for Its Use in the European Union

Molecules ◽  
2021 ◽  
Vol 26 (4) ◽  
pp. 903
Author(s):  
Gianluca Sferrazza ◽  
Gloria Brusotti ◽  
Manuela Zonfrillo ◽  
Caterina Temporini ◽  
Sara Tengattini ◽  
...  

Hovenia dulcis Thunberg is an herbal plant, belonging to the Rhamnaceae family, widespread in west Asia, USA, Australia and New Zealand, but still almost unknown in Western countries. H. dulcis has been described to possess several pharmacological properties, such as antidiabetic, anticancer, antioxidant, anti-inflammatory and hepatoprotective, especially in the hangover treatment, validating its use as an herbal remedy in the Chinese Traditional Medicine. These biological properties are related to a variety of secondary metabolites synthesized by the different plant parts. Root, bark and leaves are rich of dammarane-type triterpene saponins; dihydrokaempferol, quercetin, 3,3′,5′,5,7-pentahydroflavone and dihydromyricetin are flavonoids isolated from the seeds; fruits contain mainly dihydroflavonols, such as dihydromyricetin (or ampelopsin) and hovenodulinol, and flavonols such as myricetin and gallocatechin; alkaloids were found in root, barks (frangulanin) and seeds (perlolyrin), and organic acids (vanillic and ferulic) in hot water extract from seeds. Finally, peduncles have plenty of polysaccharides which justify the use as a food supplement. The aim of this work is to review the whole scientific production, with special focus on the last decade, in order to update phytochemistry, biological activities, nutritional properties, toxicological aspect and regulatory classification of H. dulcis extracts for its use in the European Union.

2009 ◽  
Vol 12 (3) ◽  
pp. 45-58 ◽  
Author(s):  
Renata Pisarek

The objective of this paper is to present an overview of the process of air transport liberalisation within the European Community and its influence on development of the aviation market in Poland. The paper describes the stages of air transport liberalisation in the European Community and its implementation to the Polish market. The special focus is given to problems of existing effects of air transport liberalisation and perspectives of its development. The study primarily intends to examine market structure changes of the Polish civil aviation sector and air traffic dynamics over the years of Polish integration with the European Union, presenting the most up-to-date available statistics


2021 ◽  
Vol 18 (2) ◽  
pp. 35-43
Author(s):  
Elena Grad-Rusu

Since the beginning, the European Union has believed and promoted the idea that an increase in cross-border cooperation contributes to enhanced European integration. This means that cross-border cooperation supports sustainable development along the EU’s internal and external borders, helps reduce differences in living standards and addresses common challenges across these borders. The aim of this paper is to examine the cross-border initiatives between Romania and Hungary with a special focus on the INTERREG projects, which have provided new sources of funding for cross-border activities and regional development in the RomanianHungarian border area. In this context, the cooperation has intensified in the last two decades, especially since Romania joined the EU in 2007. The research proves that cross-border projects and initiatives represent an important source of funding for this type of intervention, when no similar funding sources are available.


Author(s):  
Stefan Đurić ◽  
Bojana Lalatović

Solidarity as one of the cornerstone values of the European Union has been once again seated on the red chair and intensively discussed within the European Union and broader. After the economic recession and migrant crisis that marked the last two decades, the outbreak of the COVID-19 pandemic has once again harshly tested the fundamental objectives and values of the European Union and the responsiveness and effectiveness of its governance system on many fronts. In April, 2020 several EU Member States were among the worst affected countries worldwide and this situation soon became similar in their closest neighbourhood. It put a huge pressure on the EU to act faster, while at the same time placing this sui generis community to the test that led to revealing its strengths and weaknesses. As it happened in the previous crises, the Union launched policies and various programmes that were meant to lessen the burden of the Member States and aspiring countries caused by the crises. The objectives of the mentioned soft law instruments that the EU adopted during the COVID-19 crisis has been not only to show that EU law is equipped to react to health and economic crises rapidly but to deliver its support in terms of solidarity to its Member States and its closest neighbours facing the unprecedented health and economic crisis. This article will explore the value and implication of the solidarity principle in times of Covid-19 in its various manifestations. A special focus will be on the financial and material aspects of the EU instruments created to combat the negative consequences of the pandemic and their further impact on shaping the solidarity principle within the EU system. While examining the character and types of these mechanisms a special focus will be placed on those available to Western Balkan countries, whereas Montenegro as the “fast runner” in the EU integration process will be taken as a case study for the purpose of more detailed analyses. One of the major conclusions of the paper will be that although the speed of the EU reactions due to highly complex structure of decision making was not always satisfying for all the actors concerned, the EU once again has shown that it is reliable and that it treats the Western Balkan countries as privileged partners all for the sake of ending pandemic and launching the socio-economic recovery of the Western Balkans. Analytical and comparative methods will be dominantly relied upon throughout the paper. This will allow the authors to draw the main conclusions of the paper and assess the degree of solidarity as well as the effectiveness of the existing EU instruments that are available to Montenegro and aimed at diminishing negative consequences of the crisis.


2016 ◽  
Vol 861 ◽  
pp. 198-205
Author(s):  
Anton Pitonak ◽  
Martin Lopusniak

In the members states of the European Union, portion of buildings in the total consumption of energy represents 40%, and their portion in CO2 emissions fluctuates around 35%. The European Union is trying to protect the environment by reducing energy demand and releasing CO2 emissions into the air. Energy performance is the quantity of energy, which is necessary for heating and domestic hot water production, for cooling and ventilation and for lighting. Based on results of energy performance, individual buildings are classified into energy classes A to G. A global indicator (primary energy) is the decisive factor for final evaluation of the building. The new building must meet minimum requirements for energy performance, i.e. it must be classified to energy class A1 since 2016, and to energy class A0 since 2020. The paper analyses effect of the use of different resources of heat in a family house designed according to requirements valid since 2020, and its subsequent classification into an energy class.


2020 ◽  
Vol 45 (4) ◽  
pp. 472-486
Author(s):  
Elizaveta Samoilova

Abstract With all eyes on the recent global COVID-19 pandemic, another pandemic has been growing in the shadows: violence against women. The Council of Europe’s Istanbul Convention creates a legal framework in order to protect women against all forms of violence. Its ratification process, however, has faced considerable challenges, particularly in the Central and Eastern European Member States. This article discusses the basic elements of the Istanbul Convention, reflects on the ratification process in the EU and its Member States, and sets out the main legal issues raised in the European Parliament’s request for an opinion (A-1/19 of 22 November 2019) to the Court of Justice of the European Union. Special focus is put on the choice of the correct EU legal basis and the practices of ‘splitting’ and ‘common accord’. This article argues that the European Parliament’s request for an opinion provides the perfect opportunity for the Court of Justice of the European Union to further clarify the law and the practice of concluding mixed agreements by the EU and its Member States.


Author(s):  
Pol Rovira ◽  
Jürgen Rehm

Abstract Background Research has identified alcohol to be an important risk factor for several types of cancers. This study estimates the number of incident cancers attributable to alcohol consumption in the European Union (EU) in 2017, with a special focus on those caused by light to moderate drinking levels. Methods The attributable-fraction methodology is used to estimate the number of new cancer cases in the year 2017 in the EU caused by alcohol use, and further examines those due to light to moderate drinking levels, defined here as alcohol consumption of <20 g of pure alcohol per day. Results Light to moderate drinking levels of alcohol caused almost 23 000 new cancer cases in the EU in 2017, and accounted for 13.3% of all alcohol-attributable cancers, and 2.3% of all cases of the seven alcohol-related cancer types. Almost half of these (∼11 000 cases) were female breast cancers. Also, more than a third of the cancer cases due to light to moderate drinking resulted from a light drinking level of <1 standard drink per day (total: 37%; women: 40%; men: 32%). Conclusions Alcohol use, including light to moderate drinking, continues to cause considerable cancer burden, and efforts should be made to reduce this burden. In addition to the alcohol control policies suggested by the World Health Organization, public information campaigns and the placement of warning labels on alcohol containers advising of the cancer risk associated with alcohol use should be initiated to increase knowledge about the alcohol-cancer link.


2012 ◽  
Vol 27 (1) ◽  
pp. 26-44 ◽  
Author(s):  
Venelin I. Ganev

The manuscript analyzes negative developments in Bulgarian and Romanian politics in the aftermath of the two countries’ accession to the European Union, with a special focus on the worsening corruption problem, the destabilization of previously coherent normative frameworks, and the reversal of processes of state building. It also explores the main characteristics of a novel form of elite behavior, post-accession hooliganism, which began to emerge as soon as Bulgarian and Romanian political leaders felt strong and confident enough to disregard the demands of their West European counterparts.


Water Policy ◽  
2009 ◽  
Vol 12 (1) ◽  
pp. 70-91 ◽  
Author(s):  
V. Kanakoudis ◽  
S. Tsitsifli

Although the European Union (EU) has made some considerable progress regarding protection of water resources (tackling significant problems at national and at EU level), increased efforts are still needed to get and keep its waters clean. After 30 years of developing EU water legislation, all the involved stakeholders express this demand. In 2000, the Water Framework Directive (WFD) 2000/60/EC, establishing a framework for Community actions regarding protection of water resources, was adopted. Its implementation is now well underway, as most of the EU-Member States have fulfilled their current obligations of submitting their reports. An on-going evaluation of the WFD implementation process is attempted here, based on all available data seven years after its launch. Special focus is given to Greece regarding problems that have occurred.


2016 ◽  
Vol 25 (1) ◽  
pp. 159-178
Author(s):  
Fulvia Staiano

On February 2015, Eurostat issued a report highlighting that 65% of registered victims of human trafficking in Europe between 2010 and 2012 were citizens of the European Union (EU). Despite the seriousness of this phenomenon, EU citizens who are victims of trafficking are afforded little protection in the European legal space. First, the multi-level legal framework against trafficking applicable on the Union territory does not recognise clear residence rights to this group. Second, the general freedom of movement granted to all EU citizens under Directive 2004/38 might be precluded to victims of trafficking due to the economic prerequisites required by this instrument. It follows that the granting of refugee status to EU citizens who are victims of trafficking becomes a crucial source of protection. The safe country presumption in force between EU Member States under the so-called Aznar Protocol, however, precludes access to international protection for this group. This article critically reviews the Common European Asylum System, in search of normative and judicial interpretations capable of ensuring a stronger protection of EU citizens who are victims of trafficking. In this context, a special focus is devoted to the jurisprudence of the European Court of Human Rights and of the Court of Justice of the European Union.


2017 ◽  
Vol 8 (2) ◽  
pp. 116-127 ◽  
Author(s):  
Rebecca Niblock ◽  
Anna Oehmichen

The present article examines the developments of extradition law in Europe, with a special focus on case law in England & Wales and Germany. It explores the effects that the case law of the European Court of Human Rights and the Court of Justice of the European Union has had on extradition law within Europe, and how the tensions between mutual trust and fundamental rights protection in this area have been addressed by the two jurisdictions.


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