Catalyst-free cascade reaction of heterocyclic ketene aminals with N-substituted maleimide to synthesise bicyclic pyrrolidinone derivatives

RSC Advances ◽  
2014 ◽  
Vol 4 (52) ◽  
pp. 27582-27590 ◽  
Author(s):  
Jin Liu ◽  
Hai-Rui Zhang ◽  
Xin-Rong Lin ◽  
Sheng-Jiao Yan ◽  
Jun Lin
Keyword(s):  
Environmentally Friendly ◽  
Cascade Reaction ◽  
Efficient Synthesis ◽  
Catalyst Free ◽  
Ketene Aminals

An efficient synthesis of bicyclic pyrrolidinones via a cascade reaction of HKAs and N-substituted maleimide in an environmentally friendly medium is described. This protocol uses group-assisted purification (GAP) chemistry. The library of bicyclic pyrrolidinone derivatives has been constructed with moderate to excellent yields.

scholarly journals An efficient synthesis of new imidazo[1,2-a]pyridine-6-carbohydrazide and pyrido[1,2-a]pyrimidine-7-carbohydrazide derivatives via a five-component cascade reaction

RSC Advances ◽  
2019 ◽  
Vol 9 (13) ◽  
pp. 7218-7227 ◽  
Author(s):  
Hajar Hosseini ◽  
Mohammad Bayat
Keyword(s):  
Cascade Reaction ◽  
Efficient Synthesis ◽  
Ketene Aminals

An easy synthesis of novel and highly substituted imidazo[1,2-a]pyridines and pyrido[1,2-a]pyrimidines using heterocyclic ketene aminals.

ChemInform Abstract: Catalyst-Free Cascade Reaction of Heterocyclic Ketene Aminals with N-Substituted Maleimide to Synthesise Bicyclic Pyrrolidinone Derivatives.

ChemInform ◽  
2015 ◽  
Vol 46 (6) ◽  
pp. no-no
Author(s):  
Jin Liu ◽  
Hai-Rui Zhang ◽  
Xin-Rong Lin ◽  
Sheng-Jiao Yan ◽  
Jun Lin
Keyword(s):  
Cascade Reaction ◽  
Catalyst Free ◽  
Ketene Aminals

Cu-Catalyzed Cascade Reaction of Isoxazoles with Diaryliodonium Salts for the Synthesis of Acridines

2020 ◽  
Vol 17 (12) ◽  
pp. 944-950
Author(s):  
Shangrong Zhu ◽  
Xuechen Lu ◽  
Qiuneng Xu ◽  
Jian Li ◽  
Shenghu Yan
Keyword(s):  
Cascade Reaction ◽  
Efficient Synthesis ◽  
Acridine Derivatives ◽  
Diaryliodonium Salts

A straightforward and efficient synthesis of acridine derivatives via a copper-catalyzed cascade reaction among isoxazoles and diaryliodonium salts is achieved. Various mono-, multi-substituted and 9-substituted acridine derivatives could be obtained in moderate to good yields. The process has gone through tandem double arylation and Friedel-Crafts reactions.

Solvent-free and efficient synthesis of bicyclic 2-pyridone derivatives for endoplasmic reticulum imaging

2021 ◽  
Author(s):  
Xiaoyun Ran ◽  
Qian Zhou ◽  
Jin Zhang ◽  
Shanqiang Wang ◽  
Gui Wang ◽  
...  
Keyword(s):  
Endoplasmic Reticulum ◽  
Citric Acid ◽  
Core Structure ◽  
Solvent Free ◽  
Efficient Synthesis ◽  
The Core ◽  
Catalyst Free ◽  
Synthesis Approach ◽  
Ethylenediamine Derivatives

Started from citric acid (CA) and ethylenediamine derivatives, a solvent-free, catalyst-free and highly yield synthesis approach for bicyclic 2-pyridones was presented. Continuing to modify the core structure, a series of...

Efficient synthesis of glycosylamines in solventless conditions promoted by mechanical milling

RSC Advances ◽  
2014 ◽  
Vol 4 (68) ◽  
pp. 36350-36356 ◽  
Author(s):  
Cédric Epoune Lingome ◽  
Gwladys Pourceau ◽  
Virginie Gobert-Deveaux ◽  
Anne Wadouachi
Keyword(s):  
Mechanical Milling ◽  
Environmentally Friendly ◽  
Efficient Synthesis ◽  
Environmentally Friendly Approach

A mecanosynthesis of glycosylamines under solventless conditions was established. This environmentally friendly approach optimized with l-rhamnose, was investigated using a variety of amines and other carbohydrates.

ChemInform Abstract: An Efficient Synthesis of Quinoxalines under Catalyst-Free and Microwave-Irradiation Conditions.

ChemInform ◽  
2009 ◽  
Vol 40 (17) ◽  
Author(s):  
Jian-Feng Zhou ◽  
Gui-Xia Gong ◽  
Li-Tao An ◽  
Yu Liu ◽  
Feng-Xia Zhu ◽  
...  
Keyword(s):  
Microwave Irradiation ◽  
Efficient Synthesis ◽  
Catalyst Free

Catalyst-free efficient synthesis of polyhydroquinolines using polyethylene glycol as a solvent and evaluation of their cytotoxicity

2013 ◽  
Vol 23 (2) ◽  
pp. 1031-1036 ◽  
Author(s):  
Humani Paidepala ◽  
Siddavatam Nagendra ◽  
Venkateswarlu Saddanappu ◽  
Anthony Addlagatta ◽  
Biswanath Das
Keyword(s):  
Polyethylene Glycol ◽  
Efficient Synthesis ◽  
Catalyst Free
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