scholarly journals An efficient synthesis of new imidazo[1,2-a]pyridine-6-carbohydrazide and pyrido[1,2-a]pyrimidine-7-carbohydrazide derivatives via a five-component cascade reaction

RSC Advances ◽  
2019 ◽  
Vol 9 (13) ◽  
pp. 7218-7227 ◽  
Author(s):  
Hajar Hosseini ◽  
Mohammad Bayat
Keyword(s):  
Cascade Reaction ◽  
Efficient Synthesis ◽  
Ketene Aminals

An easy synthesis of novel and highly substituted imidazo[1,2-a]pyridines and pyrido[1,2-a]pyrimidines using heterocyclic ketene aminals.

Catalyst-free cascade reaction of heterocyclic ketene aminals with N-substituted maleimide to synthesise bicyclic pyrrolidinone derivatives

RSC Advances ◽  
2014 ◽  
Vol 4 (52) ◽  
pp. 27582-27590 ◽  
Author(s):  
Jin Liu ◽  
Hai-Rui Zhang ◽  
Xin-Rong Lin ◽  
Sheng-Jiao Yan ◽  
Jun Lin
Keyword(s):  
Environmentally Friendly ◽  
Cascade Reaction ◽  
Efficient Synthesis ◽  
Catalyst Free ◽  
Ketene Aminals

An efficient synthesis of bicyclic pyrrolidinones via a cascade reaction of HKAs and N-substituted maleimide in an environmentally friendly medium is described. This protocol uses group-assisted purification (GAP) chemistry. The library of bicyclic pyrrolidinone derivatives has been constructed with moderate to excellent yields.

Cu-Catalyzed Cascade Reaction of Isoxazoles with Diaryliodonium Salts for the Synthesis of Acridines

2020 ◽  
Vol 17 (12) ◽  
pp. 944-950
Author(s):  
Shangrong Zhu ◽  
Xuechen Lu ◽  
Qiuneng Xu ◽  
Jian Li ◽  
Shenghu Yan
Keyword(s):  
Cascade Reaction ◽  
Efficient Synthesis ◽  
Acridine Derivatives ◽  
Diaryliodonium Salts

A straightforward and efficient synthesis of acridine derivatives via a copper-catalyzed cascade reaction among isoxazoles and diaryliodonium salts is achieved. Various mono-, multi-substituted and 9-substituted acridine derivatives could be obtained in moderate to good yields. The process has gone through tandem double arylation and Friedel-Crafts reactions.

Preparation of spiro[imidazolidine-4,3′-indolin]-2′-imines via copper(i)-catalyzed formal [2 + 2 + 1] cycloaddition of 3-diazoindolin-2-imines and triazines

2019 ◽  
Vol 17 (39) ◽  
pp. 8849-8852 ◽  
Author(s):  
Yuxuan Zhou ◽  
Fanghui Ma ◽  
Ping Lu ◽  
Yanguang Wang
Keyword(s):  
Cascade Reaction ◽  
Efficient Synthesis

We report a facile and efficient synthesis of spiro[imidazolidine-4,3′-indolin]-2′-imines via a copper(i)-catalyzed cascade reaction of 3-diazoindolin-2-imines with 1,3,5-triazines.

New efficient synthesis of benzofuro[2,3-b]pyrroles utilizing a reactive nitrilium trapping approach by an acid-promoted cascade addition/cyclization sequence

2020 ◽  
Vol 44 (9) ◽  
pp. 3632-3636
Author(s):  
Sandip Gangadhar Balwe ◽  
Yeon Tae Jeong
Keyword(s):  
Cascade Reaction ◽  
Efficient Synthesis ◽  
One Pot ◽  
Highly Efficient

The first p-TSA·H2O-catalyzed highly efficient one-pot cascade reaction for the synthesis of novel fused tricyclic benzofuro[2,3-b]pyrroles has been discovered.

Visible-Light Photoredox-Catalyzed Cascade Reaction for the Synthesis of Pyrrolo[2,1-a]isoquinoline-Substituted Phosphonates

Synthesis ◽  
2018 ◽  
Vol 51 (02) ◽  
pp. 522-529 ◽  
Author(s):  
Deqing Shi ◽  
Lingna Wang ◽  
Tiancong Ma ◽  
Mingming Qiao ◽  
Qiangxian Wu ◽  
...  
Keyword(s):  
Visible Light ◽  
Visible Light Irradiation ◽  
Room Temperature ◽  
Cascade Reaction ◽  
Efficient Synthesis ◽  
Reaction Conditions ◽  
One Pot ◽  
Oxidative Aromatization ◽  
Activated Olefins ◽  
Catalyzed Oxidation

A visible-light photoredox-catalyzed oxidation/[3+2] cycloaddition/oxidative aromatization cascade reaction of [(3,4-dihydroisoquinolin-2(1H)-yl)methyl]phosphonates and activated olefins or alkynes for the efficient synthesis of potentially biological active pyrrolo[2,1-a]isoquinoline-substituted phosphonates was developed. This transformation features mild reaction conditions (i.e., visible light irradiation, room temperature), molecular oxygen (O2) as a green oxidant, simple ‘one-pot’ operation.

Copper(II)-Promoted Oxidation/[3+2]Cycloaddition/Aromatization Cascade: Efficient Synthesis of Tetrasubstituted NH-Pyrrole from Chalcones and Iminodiacetates

Synlett ◽  
2019 ◽  
Vol 30 (12) ◽  
pp. 1442-1446 ◽  
Author(s):  
Zhang-qi Lin ◽  
Chao-dong Li ◽  
Zi-chun Zhou ◽  
Shuai Xue ◽  
Jian-rong Gao ◽  
...  
Keyword(s):  
Efficient Method ◽  
Cascade Reaction ◽  
Oxidative Cyclization ◽  
Efficient Synthesis ◽  
Reaction Conditions ◽  
Highly Efficient ◽  
Wide Range ◽  
Reaction Proceeds

A simple and highly efficient method for the preparation of tetrasubstituted NH-pyrrole from a wide range of chalcones and diethyl iminodiacetates via a Cu(OAc)2-promoted oxidation/[3+2]cycloaddition/aromatization cascade reaction has been developed. This reaction proceeds through dehydrogenations, deamination, and oxidative cyclization, affording the corresponding products in good to excellent yields. This convenient methodology for constructing tetrasubstituted NH-pyrroles has several advantages over existing methods, such as the use of easily accessible chalcones and readily available diethyl iminodiacetates, and mild reaction conditions. A wide range of substrates are tolerated.

ChemInform Abstract: Efficient Synthesis of Phenanthridines Using Hendrickson Reagent Initiated Cascade Reaction under Mild Conditions.

ChemInform ◽  
2010 ◽  
Vol 41 (44) ◽  
pp. no-no
Author(s):  
Jie Xi ◽  
Qing-Li Dong ◽  
Guan-Sai Liu ◽  
Shaozhong Wang ◽  
Lin Chen ◽  
...  
Keyword(s):  
Cascade Reaction ◽  
Efficient Synthesis ◽  
Mild Conditions

ChemInform Abstract: Efficient Synthesis of 9-Aryldihydrophenanthrenes by a Cascade Reaction Involving Arynes and Styrenes.

ChemInform ◽  
2014 ◽  
Vol 45 (26) ◽  
pp. no-no
Author(s):  
Sachin Suresh Bhojgude ◽  
Anup Bhunia ◽  
Rajesh G. Gonnade ◽  
Akkattu T. Biju
Keyword(s):  
Cascade Reaction ◽  
Efficient Synthesis
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