An ultrasensitive colorimetric aptasensor for ATP based on peptide/Au nanocomposites and hemin–G-quadruplex DNAzyme

RSC Advances ◽  
2014 ◽  
Vol 4 (44) ◽  
pp. 23185-23190 ◽  
Author(s):  
Shipeng Li ◽  
Liqiang Wang ◽  
Yuanqiang Hao ◽  
Lili Zhang ◽  
Binbin Zhou ◽  
...  
Keyword(s):  
Signal Amplification ◽  
High Sensitivity ◽  
G Quadruplex ◽  
Self Assembled ◽  
Amplification Strategy ◽  
Colorimetric Aptasensor ◽  
Atp Detection

A self-assembled peptide nanosphere was firstly applied to construct biosensors. A new signal amplification strategy was proposed for colorimetric aptasensor based on PNS/AuNPs composite. The colorimetric aptasensor displayed an ultra-high sensitivity for ATP detection with a LOD of 1.35 pM.

A label-free and enzyme-free signal amplification strategy for a sensitive RNase H activity assay

Nanoscale ◽  
2017 ◽  
Vol 9 (42) ◽  
pp. 16149-16153 ◽  
Author(s):  
Chang Yeol Lee ◽  
Hyowon Jang ◽  
Ki Soo Park ◽  
Hyun Gyu Park
Keyword(s):  
Signal Amplification ◽  
Rnase H ◽  
Label Free ◽  
Activity Assay ◽  
G Quadruplex ◽  
Catalytic Hairpin Assembly ◽  
Amplification Strategy

A target-triggered catalytic hairpin assembly with a G-quadruplex specific fluorescent binder, NMM, is employed to develop a novel and sensitive RNase H activity assay.

A QCM Immunosensor for Rapid Determination of Ractopamine in Food Based on Enzyme-AuNPs for Signal Amplification and Magnetic β-Cyclodextrins for Extraction

2015 ◽  
Vol 738-739 ◽  
pp. 56-60
Author(s):  
Shu Xian Chen ◽  
Jing Liu ◽  
Dao Dong Pan ◽  
Ning Gan
Keyword(s):  
Signal Amplification ◽  
Rapid Determination ◽  
Screening Method ◽  
High Sensitivity ◽  
The Novel ◽  
Highly Sensitive ◽  
Reliable Quantification ◽  
Highly Sensitive Detection ◽  
Amplification Strategy

An enzyme amplified immunosensor for highly sensitive detection of Ractopamine (RAC) in foodstuff was developed based on quartz crystal microbalance (QCM). The high sensitivity was achieved by enzyme-AuNPs signal amplification strategy and magnetic β-cyclodextrins (β-CD) enrichment capacity. The novel QCM immunosensor which combines with the advantages of high selectivity of immunoassays and the high sensitivity of QCM has been developed for the determination of trace residues of RAC in food production. Under optimum conditions, the differences in the frequencies (∆f) of the QCM were proportional to the concentration of RAC over the range from 0.01 to 10 ng mL-1. The minimal detection limit was 0.01 ng mL-1. Due to its high sensitivity, acceptable stability and good selectivity, the immunosensor realized reliable quantification of RAC in real foodstuff. The proposed project has the potential to become a successful on-site screening method in food safety.

scholarly journals An enzyme-free molecular catalytic device: dynamically self-assembled DNA dendrimers for in situ imaging of microRNAs in live cells

2019 ◽  
Vol 10 (6) ◽  
pp. 1651-1658 ◽  
Author(s):  
Shuzhen Yue ◽  
Xinyue Song ◽  
Weiling Song ◽  
Sai Bi
Keyword(s):  
Self Assembly ◽  
Signal Amplification ◽  
High Sensitivity ◽  
Live Cells ◽  
Sensitivity And Selectivity ◽  
Catalytic Hairpin Assembly ◽  
Self Assembled ◽  
In Situ Imaging

Branched catalytic hairpin assembly is proposed for dynamic self-assembly of DNA dendrimers for signal amplification and in situ imaging of microRNAs in live cells with high sensitivity and selectivity.

A signal amplification strategy and sensing application using single gold nanoelectrodes

The Analyst ◽  
2019 ◽  
Vol 144 (1) ◽  
pp. 310-316 ◽  
Author(s):  
Dongmei Wang ◽  
Hongmei Hua ◽  
Haoran Tang ◽  
Cheng Yang ◽  
Wei Chen ◽  
...  
Keyword(s):  
Signal Amplification ◽  
High Sensitivity ◽  
Electrochemical Nanosensor ◽  
Sensing Application ◽  
Amplification Strategy ◽  
Gold Nanoelectrode

An electrochemical nanosensor was fabricated on a single gold nanoelectrode for thrombin sensing with high sensitivity via a signal amplification strategy.

Signal amplification by a self-assembled biosensor system designed on the principle of dockerin–cohesin interactions in a cellulosome complex

The Analyst ◽  
2014 ◽  
Vol 139 (19) ◽  
pp. 4790-4793 ◽  
Author(s):  
Jeong Eun Hyeon ◽  
Dae Hee Kang ◽  
Sung Ok Han
Keyword(s):  
Protein Complex ◽  
Signal Amplification ◽  
High Sensitivity ◽  
Biosensor System ◽  
Self Assembled

A self-assembled protein complex based on the principle of a cellulosome system is proposed for a biosensor with high sensitivity due to signal amplification.

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