AuNP based selective colorimetric sensor for cysteine at a wide pH range: investigation of capping molecule structure on the colorimetric sensing and catalytic properties

RSC Advances ◽  
2014 ◽  
Vol 4 (35) ◽  
pp. 18467-18472 ◽  
Author(s):  
V. Vinod Kumar ◽  
Savarimuthu Philip Anthony

Gold nanoparticles (AuNPs) stabilized with different surfactants, SDS, PEG, PVA, PVP, PSS and T-80, were synthesized and explored for cysteine colorimetric sensing and catalytic properties.

2007 ◽  
Vol 7 (11) ◽  
pp. 3754-3757 ◽  
Author(s):  
Cuong Cao ◽  
Sang Jun Sim

A sandwich immunoassay for PSA/ACT complex detection based on gold nanoparticle aggregation using two probes was developed. The functionalized colloidal gold nanoparticles (AuNPs) showed highly stable not only in the presence of high ionic strength but also in a wide pH range. The functionalized AuNPs were tagged with PSA/ACT complex monoclonal antibody and goat PSA polyclonal antibody and served as the probes to induce aggregation of the colloidal particles. As a result, PSA/ACT complex was detected at concentrations as low as 1 ng/ml. This is the first time that a new aggregation sandwich-immunoassay technique using two gold probes has been used, and the results are generally applicable to other LSPR-based immunoassays.


The Analyst ◽  
2013 ◽  
Vol 138 (15) ◽  
pp. 4370 ◽  
Author(s):  
Selvan Sukanya Ravi ◽  
Lawrence Rene Christena ◽  
Nagarajan SaiSubramanian ◽  
Savarimuthu Philip Anthony

The Analyst ◽  
2017 ◽  
Vol 142 (17) ◽  
pp. 3177-3182 ◽  
Author(s):  
Feiyang Wang ◽  
Yuexiang Lu ◽  
Jiacheng Yang ◽  
Ying Chen ◽  
Wenjie Jing ◽  
...  

We have developed a very simple colorimetric sensor array by using only unmodified gold nanoparticles and NaCl salt for discrimination of multiple proteins. The inexpensive and convenient sensor array and the ubiquitous smartphone are coupled to achieve an immediate point-of-care diagnosis without additional devices.


Chemosensors ◽  
2021 ◽  
Vol 9 (10) ◽  
pp. 290
Author(s):  
Nadezhda S. Komova ◽  
Kseniya V. Serebrennikova ◽  
Anna N. Berlina ◽  
Svetlana M. Pridvorova ◽  
Anatoly V. Zherdev ◽  
...  

The development of reliable and highly sensitive methods for heavy metal detection is a critical task for protecting the environment and human health. In this study, a qualitative colorimetric sensor that used mercaptosuccinic-acid-functionalized gold nanoparticles (MSA-AuNPs) to detect trace amounts of Fe(III) ions was developed. MSA-AuNPs were prepared using a one-step reaction, where mercaptosuccinic acid (MSA) was used for both stabilization, which was provided by the presence of two carboxyl groups, and functionalization of the gold nanoparticle (AuNP) surface. The chelating properties of MSA in the presence of Fe(III) ions and the concentration-dependent aggregation of AuNPs showed the effectiveness of MSA-AuNPs as a sensing probe with the use of an absorbance ratio of A530/A650 as an analytical signal in the developed qualitative assay. Furthermore, the obvious Fe(III)-dependent change in the color of the MSA-AuNP solution from red to gray-blue made it possible to visually assess the metal content in a concentration above the detection limit with an assay time of less than 1 min. The detection limit that was achieved (23 ng/mL) using the proposed colorimetric sensor is more than 10 times lower than the maximum allowable concentration for drinking water defined by the World Health Organization (WHO). The MSA-AuNPs were successfully applied for Fe(III) determination in tap, spring, and drinking water, with a recovery range from 89.6 to 126%. Thus, the practicality of the MSA-AuNP-based sensor and its potential for detecting Fe(III) in real water samples were confirmed by the rapidity of testing and its high sensitivity and selectivity in the presence of competing metal ions.


2019 ◽  
Vol 1 (2) ◽  
pp. 486-489 ◽  
Author(s):  
Xiaoyi Ma ◽  
Xinyue Kou ◽  
Yuanyuan Xu ◽  
Dawei Yang ◽  
Peng Miao

We have developed a highly sensitive colorimetric sensor for the detection of heparin based on its anti-aggregation effect of the PDDA–gold nanoparticle colloidal system.


2015 ◽  
Vol 26 (49) ◽  
pp. 495101 ◽  
Author(s):  
Marcin Drozd ◽  
Mariusz Pietrzak ◽  
Paweł Parzuchowski ◽  
Marta Mazurkiewicz-Pawlicka ◽  
Elżbieta Malinowska

2007 ◽  
Vol 7 (11) ◽  
pp. 3754-3757 ◽  
Author(s):  
Cuong Cao ◽  
Sang Jun Sim

A sandwich immunoassay for PSA/ACT complex detection based on gold nanoparticle aggregation using two probes was developed. The functionalized colloidal gold nanoparticles (AuNPs) showed highly stable not only in the presence of high ionic strength but also in a wide pH range. The functionalized AuNPs were tagged with PSA/ACT complex monoclonal antibody and goat PSA polyclonal antibody and served as the probes to induce aggregation of the colloidal particles. As a result, PSA/ACT complex was detected at concentrations as low as 1 ng/ml. This is the first time that a new aggregation sandwich-immunoassay technique using two gold probes has been used, and the results are generally applicable to other LSPR-based immunoassays.


1991 ◽  
Vol 56 (12) ◽  
pp. 2791-2799 ◽  
Author(s):  
Juan A. Squella ◽  
Luis J. Nuñez-Vergara ◽  
Hernan Rodríguez ◽  
Amelia Márquez ◽  
Jose M. Rodríguez-Mellado ◽  
...  

Five N-p-phenyl substituted benzamidines were studied by DC and DP polarography in a wide pH range. Coulometric results show that the overall processes are four-electron reductions. Logarithmic analysis of the waves indicate that the process are irreversible. The influence of the pH on the polarographic parameters was also studied. A UV spectrophotometric study was performed in the pH range 2-13. In basic media some variations in the absorption bands were observed due to the dissociation of the amidine group. A determination of the pK values was made by deconvolution of the spectra. Correlations of both the electrochemical parameters and spectrophotometric pK values with the Hammett substituent constants were obtained.


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