scholarly journals Colorimetric sensing strategy for heparin assay based on PDDA-induced aggregation of gold nanoparticles

2019 ◽  
Vol 1 (2) ◽  
pp. 486-489 ◽  
Author(s):  
Xiaoyi Ma ◽  
Xinyue Kou ◽  
Yuanyuan Xu ◽  
Dawei Yang ◽  
Peng Miao
Keyword(s):  
Gold Nanoparticles ◽  
Gold Nanoparticle ◽  
Colorimetric Sensor ◽  
Colloidal System ◽  
Colorimetric Sensing ◽  
Aggregation Effect ◽  
System P ◽  
Highly Sensitive ◽  
Induced Aggregation

We have developed a highly sensitive colorimetric sensor for the detection of heparin based on its anti-aggregation effect of the PDDA–gold nanoparticle colloidal system.

scholarly journals Mercaptosuccinic-Acid-Functionalized Gold Nanoparticles for Highly Sensitive Colorimetric Sensing of Fe(III) Ions

Chemosensors ◽  
2021 ◽  
Vol 9 (10) ◽  
pp. 290
Author(s):  
Nadezhda S. Komova ◽  
Kseniya V. Serebrennikova ◽  
Anna N. Berlina ◽  
Svetlana M. Pridvorova ◽  
Anatoly V. Zherdev ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Drinking Water ◽  
Detection Limit ◽  
Analytical Signal ◽  
Colorimetric Sensor ◽  
World Health ◽  
Colorimetric Sensing ◽  
Functionalized Gold Nanoparticles ◽  
Mercaptosuccinic Acid ◽  
Highly Sensitive

The development of reliable and highly sensitive methods for heavy metal detection is a critical task for protecting the environment and human health. In this study, a qualitative colorimetric sensor that used mercaptosuccinic-acid-functionalized gold nanoparticles (MSA-AuNPs) to detect trace amounts of Fe(III) ions was developed. MSA-AuNPs were prepared using a one-step reaction, where mercaptosuccinic acid (MSA) was used for both stabilization, which was provided by the presence of two carboxyl groups, and functionalization of the gold nanoparticle (AuNP) surface. The chelating properties of MSA in the presence of Fe(III) ions and the concentration-dependent aggregation of AuNPs showed the effectiveness of MSA-AuNPs as a sensing probe with the use of an absorbance ratio of A530/A650 as an analytical signal in the developed qualitative assay. Furthermore, the obvious Fe(III)-dependent change in the color of the MSA-AuNP solution from red to gray-blue made it possible to visually assess the metal content in a concentration above the detection limit with an assay time of less than 1 min. The detection limit that was achieved (23 ng/mL) using the proposed colorimetric sensor is more than 10 times lower than the maximum allowable concentration for drinking water defined by the World Health Organization (WHO). The MSA-AuNPs were successfully applied for Fe(III) determination in tap, spring, and drinking water, with a recovery range from 89.6 to 126%. Thus, the practicality of the MSA-AuNP-based sensor and its potential for detecting Fe(III) in real water samples were confirmed by the rapidity of testing and its high sensitivity and selectivity in the presence of competing metal ions.

scholarly journals Application of Gold-Nanoparticle Colorimetric Sensing to Rapid Food Safety Screening

Sensors ◽  
2018 ◽  
Vol 18 (12) ◽  
pp. 4166 ◽  
Author(s):  
Guangyang Liu ◽  
Meng Lu ◽  
Xiaodong Huang ◽  
Tengfei Li ◽  
Donghui Xu
Keyword(s):  
Gold Nanoparticles ◽  
Gold Nanoparticle ◽  
Rapid Testing ◽  
Colorimetric Sensing ◽  
Preparation Methods ◽  
Particle Spacing ◽  
Advantages And Disadvantages ◽  
Site Monitoring ◽  
Biological Affinity ◽  
Food Quality And Safety

Due to their unique optical properties, narrow size distributions, and good biological affinity, gold nanoparticles have been widely applied in sensing analysis, catalytic, environmental monitoring, and disease therapy. The color of a gold nanoparticle solution and its maximum characteristic absorption wavelength will change with the particle size and inter-particle spacing. These properties are often used in the detection of hazardous chemicals, such as pesticide residues, heavy metals, banned additives, and biotoxins, in food. Because the gold nanoparticles-colorimetric sensing strategy is simple, quick, and sensitive, this method has extensive applications in real-time on-site monitoring and rapid testing of food quality and safety. Herein, we review the preparation methods, functional modification, photochemical properties, and applications of gold nanoparticle sensors in rapid testing. In addition, we elaborate on the colorimetric sensing mechanisms. Finally, we discuss the advantages and disadvantages of colorimetric sensors based on gold nanoparticles, and directions for future development.

A highly sensitive gold nanoparticle bioprobe based electrochemical immunosensor using screen printed graphene biochip

RSC Advances ◽  
2014 ◽  
Vol 4 (102) ◽  
pp. 58460-58466 ◽  
Author(s):  
Syazana Abdullah Lim ◽  
Hiroyuki Yoshikawa ◽  
Eiichi Tamiya ◽  
Hartini Mohd Yasin ◽  
Minhaz Uddin Ahmed
Keyword(s):  
Gold Nanoparticles ◽  
Gold Nanoparticle ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Electrode Material ◽  
Electrochemical Immunosensor ◽  
Highly Sensitive ◽  
Electrochemical Label ◽  
Screen Printed

This study describes a highly sensitive electrochemical immunosensor for the detection of human chorionic gonadotropin (hCG) that uses gold nanoparticles (AuNP) as the electrochemical label and graphene as electrode material.

scholarly journals Tannic Acid-Capped Gold Nanoparticles as a Novel Nanozyme for Colorimetric Determination of Pb2+ Ions

Chemosensors ◽  
2021 ◽  
Vol 9 (12) ◽  
pp. 332
Author(s):  
Kseniya V. Serebrennikova ◽  
Nadezhda S. Komova ◽  
Anna N. Berlina ◽  
Anatoly V. Zherdev ◽  
Boris B. Dzantiev
Keyword(s):  
Gold Nanoparticles ◽  
Tannic Acid ◽  
Oxidation Reaction ◽  
Limit Of Detection ◽  
Colorimetric Sensor ◽  
Spring Water ◽  
Colorimetric Determination ◽  
Highly Sensitive ◽  
Maximal Sensitivity

In this study, tannic acid-modified gold nanoparticles were found to have superior nanozyme activity and catalyze the oxidation reaction of 3,3′,5,5′-tetramethylbenzidine in the presence of hydrogen peroxide. Enhancing the catalytic activity of the nanozyme by Pb2+ ions caused by selectively binding metal ions by the tannic acid-capped surface of gold nanoparticles makes them an ideal colorimetric probe for Pb2+. The parameters of the reaction, including pH, incubation time, and concentration of components, were optimized to reach maximal sensitivity of Pb2+ detection. The absorption change is directly proportional to the Pb2+ concentration and allows the determination of Pb2+ ions within 10 min. The colorimetric sensor is characterized by a wide linear range from 25 to 500 ng×mL−1 with a low limit of detection of 11.3 ng×mL−1. The highly sensitive and selective Pb2+ detection in tap, drinking, and spring water revealed the feasibility and applicability of the developed colorimetric sensor.

scholarly journals A label-free protamine-assisted colorimetric sensor for highly sensitive detection of S1 nuclease activity

The Analyst ◽  
2020 ◽  
Vol 145 (7) ◽  
pp. 2774-2778
Author(s):  
Jiahui Wen ◽  
Yongming Liu ◽  
Jingwen Li ◽  
Hao Lin ◽  
Yiran Zheng ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Colorimetric Method ◽  
Nuclease Activity ◽  
Colorimetric Sensor ◽  
Sensitive Detection ◽  
Label Free ◽  
S1 Nuclease ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

A label-free, simple and rapid colorimetric method for the sensitive detection of S1 nuclease activity based on protamine-assisted aggregation of gold nanoparticles.

Gold nanoparticle-based nano-probe for the colorimetric sensing of Cr3+and Cr2O72−by the coordination strategy

Nanoscale ◽  
2017 ◽  
Vol 9 (48) ◽  
pp. 19139-19144 ◽  
Author(s):  
Jianjun Du ◽  
Haoying Ge ◽  
Quanyong Gu ◽  
Hong Du ◽  
Jiangli Fan ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Quantitative Determination ◽  
Gold Nanoparticle ◽  
Colorimetric Sensing ◽  
Coordination Strategy

The Eyedropper function in Microsoft PowerPoint was introduced into the gold nanoparticles-based colorimetric recognition of Cr3+and Cr2O72−, which makes the quantitative determination easier, more convenient and more accurate.

Highly sensitive and rapid visual detection of ricin using unmodified gold nanoparticle probes

RSC Advances ◽  
2014 ◽  
Vol 4 (83) ◽  
pp. 43998-44003 ◽  
Author(s):  
Jingting Hu ◽  
Haichao Dai ◽  
Yujing Sun ◽  
Pengjuan Ni ◽  
Yilin Wang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Gold Nanoparticle ◽  
Visual Detection ◽  
Nanoparticle Probes ◽  
Highly Sensitive

A sensitive aptamer-based colorimetric biosensor for the detection of ricin using unmodified gold nanoparticles as probe was developed.

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