scholarly journals Microfluidic device (ExoChip) for on-chip isolation, quantification and characterization of circulating exosomes

Lab on a Chip ◽  
2014 ◽  
Vol 14 (11) ◽  
pp. 1891-1900 ◽  
Author(s):  
Shailender Singh Kanwar ◽  
Christopher James Dunlay ◽  
Diane M. Simeone ◽  
Sunitha Nagrath
Keyword(s):  
Clinical Application ◽  
Microfluidic Device ◽  
On Chip

Microfluidic all-in-one device “ExoChip” for isolation, quantification and analysis of circulatory exosomes: bridging the gap between technology and clinical application.

Characterization of size-dependent mechanical properties of tip-growing cells using a lab-on-chip device

Lab on a Chip ◽  
2017 ◽  
Vol 17 (1) ◽  
pp. 82-90 ◽  
Author(s):  
Chengzhi Hu ◽  
Gautam Munglani ◽  
Hannes Vogler ◽  
Tohnyui Ndinyanka Fabrice ◽  
Naveen Shamsudhin ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Cell Wall ◽  
Young’S Modulus ◽  
Microfluidic Device ◽  
Young's Modulus ◽  
Turgor Pressure ◽  
Lab On Chip ◽  
Size Dependent ◽  
On Chip

A microfluidic device can trap and indent tip-growing cells for quantification of turgor pressure and cell wall Young's modulus.

scholarly journals A microfluidic perfusion approach for on-chip characterization of the transport properties of human oocytes

Lab on a Chip ◽  
2017 ◽  
Vol 17 (7) ◽  
pp. 1297-1305 ◽  
Author(s):  
Gang Zhao ◽  
Zhiguo Zhang ◽  
Yuntian Zhang ◽  
Zhongrong Chen ◽  
Dan Niu ◽  
...  
Keyword(s):  
Transport Properties ◽  
Microfluidic Device ◽  
Osmotic Shock ◽  
Human Oocytes ◽  
Microfluidic Perfusion ◽  
On Chip

A novel sandwich structured microfluidic device based approach that allows for on-chip characterization of the transport properties of human oocytes under innocuous osmotic shock or injury to the cells.

scholarly journals On-chip characterization of cryoprotective agent mixtures using an EWOD-based digital microfluidic device

Lab on a Chip ◽  
2011 ◽  
Vol 11 (13) ◽  
pp. 2212 ◽  
Author(s):  
Sinwook Park ◽  
Pavithra A. L. Wijethunga ◽  
Hyejin Moon ◽  
Bumsoo Han
Keyword(s):  
Microfluidic Device ◽  
Cryoprotective Agent ◽  
On Chip ◽  
Digital Microfluidic

scholarly journals Design and Manufacturing of a Disposable, Cyclo-Olefin Copolymer, Microfluidic Device for a Biosensor †

Sensors ◽  
2019 ◽  
Vol 19 (5) ◽  
pp. 1178 ◽  
Author(s):  
Jorge Prada ◽  
Christina Cordes ◽  
Carsten Harms ◽  
Walter Lang
Keyword(s):  
Microfluidic Device ◽  
Heating Temperature ◽  
Low Cost ◽  
Reaction Chamber ◽  
Microfluidic System ◽  
Heating Process ◽  
Design And Manufacturing ◽  
On Chip ◽  
Working Parameters ◽  
Auto Fluorescence

This contribution outlines the design and manufacturing of a microfluidic device implemented as a biosensor for retrieval and detection of bacteria RNA. The device is fully made of Cyclo-Olefin Copolymer (COC), which features low auto-fluorescence, biocompatibility and manufacturability by hot-embossing. The RNA retrieval was carried on after bacteria heat-lysis by an on-chip micro-heater, whose function was characterized at different working parameters. Carbon resistive temperature sensors were tested, characterized and printed on the biochip sealing film to monitor the heating process. Off-chip and on-chip processed RNA were hybridized with capture probes on the reaction chamber surface and identification was achieved by detection of fluorescence tags. The application of the mentioned techniques and materials proved to allow the development of low-cost, disposable albeit multi-functional microfluidic system, performing heating, temperature sensing and chemical reaction processes in the same device. By proving its effectiveness, this device contributes a reference to show the integration potential of fully thermoplastic devices in biosensor systems.

scholarly journals Demonstration of an integrated nanophotonic chip-scale alkali vapor magnetometer using inverse design

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Yoel Sebbag ◽  
Eliran Talker ◽  
Alex Naiman ◽  
Yefim Barash ◽  
Uriel Levy
Keyword(s):  
Spatial Resolution ◽  
Near Field ◽  
Computer Assisted ◽  
Experimental Characterization ◽  
Optical Isolation ◽  
New Concepts ◽  
On Chip ◽  
The Cost ◽  
Micrometer Scale

AbstractRecently, there has been growing interest in the miniaturization and integration of atomic-based quantum technologies. In addition to the obvious advantages brought by such integration in facilitating mass production, reducing the footprint, and reducing the cost, the flexibility offered by on-chip integration enables the development of new concepts and capabilities. In particular, recent advanced techniques based on computer-assisted optimization algorithms enable the development of newly engineered photonic structures with unconventional functionalities. Taking this concept further, we hereby demonstrate the design, fabrication, and experimental characterization of an integrated nanophotonic-atomic chip magnetometer based on alkali vapor with a micrometer-scale spatial resolution and a magnetic sensitivity of 700 pT/√Hz. The presented platform paves the way for future applications using integrated photonic–atomic chips, including high-spatial-resolution magnetometry, near-field vectorial imaging, magnetically induced switching, and optical isolation.

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