Interaction between calf thymus DNA and cationic bottle-brush copolymers: equilibrium and stopped-flow kinetic studies

2015 ◽  
Vol 17 (4) ◽  
pp. 2366-2377 ◽  
Author(s):  
Debabrata Dey ◽  
Chiranjit Maiti ◽  
Souvik Maiti ◽  
Dibakar Dhara
Keyword(s):  
Kinetic Studies ◽  
Calf Thymus Dna ◽  
Stopped Flow ◽  
Dna Compaction ◽  
Compaction Behavior ◽  
Calf Thymus ◽  
Bottle Brush ◽  
Kinetics Of

Polyplex formation betweenctDNA and PEGylated cationic bottle-brush copolymers: PEG influences the DNA compaction behavior and the kinetics of polyplex formation.

Stopped-Flow Kinetic Studies of Poly(amidoamine) Dendrimer–Calf Thymus DNA To Form Dendriplexes

2013 ◽  
Vol 117 (44) ◽  
pp. 13767-13774 ◽  
Author(s):  
Debabrata Dey ◽  
Santosh Kumar ◽  
Souvik Maiti ◽  
Dibakar Dhara
Keyword(s):  
Kinetic Studies ◽  
Calf Thymus Dna ◽  
Stopped Flow ◽  
Calf Thymus

scholarly journals Synthesis of New Five Coordinated Copper(II) and Nickel(II) Complexes of L-Valine and Kinetic Study of Copper(II) with Calf Thymus DNA

2002 ◽  
Vol 9 (1-2) ◽  
pp. 81-90 ◽  
Author(s):  
Aijaz Ahmad Tak ◽  
Farukh Arjmand ◽  
Sartaj Tabassum
Keyword(s):  
Metal Ion ◽  
Binding Mode ◽  
Molar Conductance ◽  
Order Conditions ◽  
Calf Thymus Dna ◽  
First Order ◽  
Reversible Redox ◽  
Calf Thymus ◽  
Vis Spectroscopy ◽  
Kinetics Of

Five coordinated novel complexes of CuII and NiII have been synthesized from benzil and 1,3- diaminopropane-CuII/NiII complex and characterized by elemental analysis, i.r., n.m.r., e.p.r, molar conductance and u.v-vis, spectroscopy. The complexes are ionic in nature and exhibit pentaeoordinated geometry around the metal ion. The reaction kinetics of C25H36N5O2CuCl with calf thymus DNA was studied by u.v-vis, spectroscopy in aqueous medium. The complex after interaction with calf thymus DNA shows shift in the absorption spectrum and hypochromicity indicating an intercalative binding mode. The Kobs values have been calculated under pseudo-first order conditions. The redox behaviour of complex C25H36N5O2CuCl in the presence and in the absence of calf thymus DNA in the aqueous solution has been investigated by cyclic voltammetry. The cyclic voitammogram exhibits one quasi-reversible redox wave corresponding to CuII/CuI redox couple with E1/2 values of -0.377 and -0.237 V respectively at a scan rate of 0.1Vs-1 .On interaction with calf thymus DNA, the complex C25H36N5O2CuCl exhibits shifts in both Ep as well as in E1/2 values, indicating strong binding of the complex to the calf thymus DNA.

Solvent Effects on the Kinetics of the Interaction of 1-Pyrenecarboxaldehyde with Calf Thymus DNA

2010 ◽  
Vol 114 (13) ◽  
pp. 4686-4691 ◽  
Author(s):  
Fernando Secco ◽  
Marcella Venturini ◽  
Tarita Biver ◽  
Francisco Sánchez ◽  
Rafael Prado-Gotor ◽  
...  
Keyword(s):  
Solvent Effects ◽  
Calf Thymus Dna ◽  
Calf Thymus ◽  
Kinetics Of

Stopped-flow kinetic analysis of the interaction of anthraquinone anticancer drugs with calf thymus DNA, poly[d(G-C)].cntdot.poly[d(G-C)], and poly[d(A-T)].cntdot.poly[d(A-T)]

Biochemistry ◽  
1986 ◽  
Vol 25 (20) ◽  
pp. 5933-5940 ◽  
Author(s):  
C. R. Krishnamoorthy ◽  
Shau Fong Yen ◽  
J. C. Smith ◽  
J. William Lown ◽  
W. David Wilson
Keyword(s):  
Kinetic Analysis ◽  
Anticancer Drugs ◽  
Calf Thymus Dna ◽  
Stopped Flow ◽  
Calf Thymus

Etude du système acridine orange – poly(C) et de son interaction avec les complexes du palladium(II)

1984 ◽  
Vol 62 (9) ◽  
pp. 1681-1686 ◽  
Author(s):  
Robert Ménard ◽  
Miklos Zador
Keyword(s):  
Acridine Orange ◽  
Thermodynamic Parameters ◽  
Rate Constant ◽  
Kinetic Studies ◽  
Stopped Flow ◽  
Flow Method ◽  
Polycytidylic Acid ◽  
Low Concentrations ◽  
C Complex ◽  
Kinetics Of

The complex formed between acridine orange (AO) and polycytidylic acid (poly(C)) was studied by spectrophotometry and spectrofluorometry. The complex was characterized by its stoichiometry, structure, and the thermodynamic parameters of its formation. The results are in agreement with an external aggregation of the protonated dye along the negatively charged poly(C) chain and indicate that approximately two AO molecules are bound per nucleotide unit of poly(C). The kinetics of the reaction between this complex and a Pd(II) complex was studied by the stopped-flow method. The addition of (dien)Pd(II) to the AO–poly(C) complex leads to the dissociation of the latter, due to fixation of the Pd(II) complex to the N3 site of the cytosine base of poly(C). The rate constant for the AO liberation, extrapolated at zero AO concentration, corresponds to the rate constant of Pd(II) fixation on poly(C). This indicates that AO can be used as an indicator for this reaction and allows kinetic studies at very low concentrations (≤ 5 × 10−6 M).

Equilibria and kinetics of the intercalation of Pt-proflavine and proflavine into calf thymus DNA

2003 ◽  
Vol 418 (1) ◽  
pp. 63-70 ◽  
Author(s):  
Tarita Biver ◽  
Fernando Secco ◽  
Maria Rosaria Tinè ◽  
Marcella Venturini
Keyword(s):  
Calf Thymus Dna ◽  
Calf Thymus ◽  
Kinetics Of

scholarly journals Reassociation kinetics of three satellite components of calf thymus DNA

1975 ◽  
Vol 2 (2) ◽  
pp. 185-196 ◽  
Author(s):  
Hana Votavová ◽  
Jaroslav Šponar
Keyword(s):  
Calf Thymus Dna ◽  
Reassociation Kinetics ◽  
Calf Thymus ◽  
Kinetics Of
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