scholarly journals Reassociation kinetics of three satellite components of calf thymus DNA

1975 ◽  
Vol 2 (2) ◽  
pp. 185-196 ◽  
Author(s):  
Hana Votavová ◽  
Jaroslav Šponar
Keyword(s):  
Calf Thymus Dna ◽  
Reassociation Kinetics ◽  
Calf Thymus ◽  
Kinetics Of

scholarly journals Synthesis of New Five Coordinated Copper(II) and Nickel(II) Complexes of L-Valine and Kinetic Study of Copper(II) with Calf Thymus DNA

2002 ◽  
Vol 9 (1-2) ◽  
pp. 81-90 ◽  
Author(s):  
Aijaz Ahmad Tak ◽  
Farukh Arjmand ◽  
Sartaj Tabassum
Keyword(s):  
Metal Ion ◽  
Binding Mode ◽  
Molar Conductance ◽  
Order Conditions ◽  
Calf Thymus Dna ◽  
First Order ◽  
Reversible Redox ◽  
Calf Thymus ◽  
Vis Spectroscopy ◽  
Kinetics Of

Five coordinated novel complexes of CuII and NiII have been synthesized from benzil and 1,3- diaminopropane-CuII/NiII complex and characterized by elemental analysis, i.r., n.m.r., e.p.r, molar conductance and u.v-vis, spectroscopy. The complexes are ionic in nature and exhibit pentaeoordinated geometry around the metal ion. The reaction kinetics of C25H36N5O2CuCl with calf thymus DNA was studied by u.v-vis, spectroscopy in aqueous medium. The complex after interaction with calf thymus DNA shows shift in the absorption spectrum and hypochromicity indicating an intercalative binding mode. The Kobs values have been calculated under pseudo-first order conditions. The redox behaviour of complex C25H36N5O2CuCl in the presence and in the absence of calf thymus DNA in the aqueous solution has been investigated by cyclic voltammetry. The cyclic voitammogram exhibits one quasi-reversible redox wave corresponding to CuII/CuI redox couple with E1/2 values of -0.377 and -0.237 V respectively at a scan rate of 0.1Vs-1 .On interaction with calf thymus DNA, the complex C25H36N5O2CuCl exhibits shifts in both Ep as well as in E1/2 values, indicating strong binding of the complex to the calf thymus DNA.

Solvent Effects on the Kinetics of the Interaction of 1-Pyrenecarboxaldehyde with Calf Thymus DNA

2010 ◽  
Vol 114 (13) ◽  
pp. 4686-4691 ◽  
Author(s):  
Fernando Secco ◽  
Marcella Venturini ◽  
Tarita Biver ◽  
Francisco Sánchez ◽  
Rafael Prado-Gotor ◽  
...  
Keyword(s):  
Solvent Effects ◽  
Calf Thymus Dna ◽  
Calf Thymus ◽  
Kinetics Of

Equilibria and kinetics of the intercalation of Pt-proflavine and proflavine into calf thymus DNA

2003 ◽  
Vol 418 (1) ◽  
pp. 63-70 ◽  
Author(s):  
Tarita Biver ◽  
Fernando Secco ◽  
Maria Rosaria Tinè ◽  
Marcella Venturini
Keyword(s):  
Calf Thymus Dna ◽  
Calf Thymus ◽  
Kinetics Of

Interaction between calf thymus DNA and cationic bottle-brush copolymers: equilibrium and stopped-flow kinetic studies

2015 ◽  
Vol 17 (4) ◽  
pp. 2366-2377 ◽  
Author(s):  
Debabrata Dey ◽  
Chiranjit Maiti ◽  
Souvik Maiti ◽  
Dibakar Dhara
Keyword(s):  
Kinetic Studies ◽  
Calf Thymus Dna ◽  
Stopped Flow ◽  
Dna Compaction ◽  
Compaction Behavior ◽  
Calf Thymus ◽  
Bottle Brush ◽  
Kinetics Of

Polyplex formation betweenctDNA and PEGylated cationic bottle-brush copolymers: PEG influences the DNA compaction behavior and the kinetics of polyplex formation.

Molecular Transformations in DNA under the Influence of UV-radiation

2020 ◽  
Vol 04 ◽  
Author(s):  
Vigen G. Barkhudaryan ◽  
Gayane V. Ananyan ◽  
Nelli H. Karapetyan
Keyword(s):  
Uv Radiation ◽  
Uv Irradiation ◽  
Absorption Spectroscopy ◽  
Calf Thymus Dna ◽  
Dilute Solutions ◽  
Concentrated Solutions ◽  
Buffer Solution ◽  
Low Concentration ◽  
Calf Thymus ◽  
Dna Solutions

Background: The processes of destruction and crosslinking of macromolecules occur simultaneously under the influence of ultraviolet (UV) radiation in synthetic polymers, dry DNA and their concentrated solutions. Objective: The effect of UV radiation on calf thymus DNA in dilute solutions subjected to UV- irradiation was studied in this work. Method: The calf thymus DNA was studied in dilute solutions using viscometry, absorption spectroscopy and electrophoresis. Results: It was shown, that at a low concentration of DNA in the buffer solution ([DNA] = 85 μg / ml) under the influence of UV radiation, the processes of destruction of macromolecules and an increase in their flexibility predominate, which is accompanied by a gradual decrease in the viscosity of their solution. In addition, due to the low concentration of the solution, intramolecular crosslinking of macromolecules predominates, which also reduces their size and, consequently, the viscosity of the solution. Conclusion: It was concluded, that in dilute DNA solutions, due to the predominance of the processes of intramolecular crosslinking of macromolecules over intermolecular, only constant processes of decreasing the sizes of DNA macromolecules occur. As a result, its solubility remains virtually unchanged during UV irradiation. The described comments are also excellently confirmed by the results of absorption spectroscopy and electrophoresis

Ce(IV)-mediated formation of benzenediazonium ion from a non-aminoazo dye, 1-phenylazo-2-hydroxy-naphthalene (Sudan I) and its binding to DNA

1989 ◽  
Vol 54 (7) ◽  
pp. 2021-2026
Author(s):  
Marie Stiborová ◽  
Befekadu Asfaw ◽  
Pavel Anzenbacher
Keyword(s):  
Azo Dyes ◽  
Acidic Medium ◽  
Model System ◽  
Calf Thymus Dna ◽  
Suitable Model ◽  
Principal Product ◽  
Calf Thymus ◽  
Sudan I ◽  
A Minor

Ce(IV) ions in acidic medium convert a carcinogenic non-aminoazo dye, 1-phenylazo-2-hydroxy-naphthalene (Sudan I) into an ultimate carcinogen, which binds to calf thymus DNA. The principal product of Sudan I oxidation by the Ce(IV) system is the benzenediazonium ion. A minor product is the dihydroxyderivative of Sudan I, 1-(4-hydroxyphenylazo)-2,6-dihydroxynaphthalene. Other minor coloured products (yellow and brown) were not identified. The principal product (the benzenediazonium ion) is responsible for the carcinogenicity of Sudan I, as it covalently binds to DNA. Ce(IV) ions in acidic medium represent a suitable model system, which imitates the activation route of carcinogenic azo dyes.

Investigation of Anti-Cancer Drug Nimustine Interaction with Calf Thymus DNA

MAPAN ◽  
2016 ◽  
Vol 31 (3) ◽  
pp. 169-175 ◽  
Author(s):  
Deepti Chadha ◽  
Shweta Agarwal ◽  
Ranjana Mehrotra
Keyword(s):  
Calf Thymus Dna ◽  
Cancer Drug ◽  
Calf Thymus ◽  
Anti Cancer
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