Boronic acid chemistry in MALDI MS: a step forward in designing a reactive matrix with molecular recognition capabilities

2014 ◽  
Vol 50 (33) ◽  
pp. 4322 ◽  
Author(s):  
A. Monopoli ◽  
C. D. Calvano ◽  
A. Nacci ◽  
F. Palmisano
Keyword(s):  
Molecular Recognition ◽  
Boronic Acid ◽  
Maldi Ms ◽  
Reactive Matrix

Arylboronic Acids in Self-condensation of Glucosamines Forming Deoxyfructosazine, Catalysts or Reagents?

2019 ◽  
Author(s):  
Meifeng Wang ◽  
Gan Zhu ◽  
Yiqun Li ◽  
Liuqun Gu
Keyword(s):  
Molecular Recognition ◽  
Boric Acid ◽  
Boronic Acid ◽  
Catalytic Mechanism ◽  
Organic Transformations ◽  
Food Industries ◽  
Arylboronic Acids ◽  
Excess Amount ◽  
Phenyl Boronic Acid ◽  
Boron Acid

Arylboronic acids were widely used as efficient catalysts in direct amide formation and other organic transformations. Surprisingly, reports on their use as catalysts in carbohydrates synthesis are very rare even though boron acid-diol complexation was extensively investigated in molecular recognition for saccharides and so on. Here we developed an efficient arylboronic acids catalyzed dimerization of glucosamines forming deoxyfructosazine which is important compound in pharmaceutical and food industries, against a commonly held belief that excess amount of phenyl boronic acid (or boric acid) is a must. A catalytic mechanism was also proposed and arylboronic acids instead of their boronates was identified as catalysts.

4-Hydrazinoquinazoline acting as reactive matrix for rapid and sensitive analysis of neutral and sialylated glycans using MALDI MS

The Analyst ◽  
2021 ◽  
Author(s):  
Ling Ling ◽  
Shaoning Yu ◽  
Chuanfan Ding
Keyword(s):  
Laser Desorption ◽  
Direct Analysis ◽  
Maldi Ms ◽  
Ionization Mass ◽  
Laser Desorption Ionization ◽  
Chemical Derivatization ◽  
Reactive Matrix ◽  
Matrix Assisted Laser ◽  
Matrix Assisted Laser Desorption ◽  
Limited Sensitivity

Direct analysis of glycans by matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) presents limited sensitivity due to the lower ionization efficiency of glycans. Various chemical derivatization methods have been developed...

scholarly journals Arylboronic Acids in Self-condensation of Glucosamines Forming Deoxyfructosazine, Catalysts or Reagents?

2018 ◽  
Author(s):  
Meifeng Wang ◽  
Gan Zhu ◽  
Yiqun Li ◽  
Liuqun Gu
Keyword(s):  
Molecular Recognition ◽  
Boric Acid ◽  
Boronic Acid ◽  
Catalytic Mechanism ◽  
Organic Transformations ◽  
Food Industries ◽  
Arylboronic Acids ◽  
Excess Amount ◽  
Phenyl Boronic Acid ◽  
Boron Acid

Arylboronic acids were widely used as efficient catalysts in direct amide formation and other organic transformations. Surprisingly, reports on their use as catalysts in carbohydrates synthesis are very rare even though boron acid-diol complexation was extensively investigated in molecular recognition for saccharides and so on. Here we developed an efficient arylboronic acids catalyzed dimerization of glucosamines forming deoxyfructosazine which is important compound in pharmaceutical and food industries, against a commonly held belief that excess amount of phenyl boronic acid (or boric acid) is a must. A catalytic mechanism was also proposed and arylboronic acids instead of their boronates was identified as catalysts.

2-Phenyl-3-(p-aminophenyl) Acrylonitrile: A Reactive Matrix for Sensitive and Selective Analysis of Glycans by MALDI-MS

2019 ◽  
Vol 91 (14) ◽  
pp. 8801-8807
Author(s):  
Ling Ling ◽  
Chunsheng Xiao ◽  
Yao Ma ◽  
Liyan Jiang ◽  
Sheng Wang ◽  
...  
Keyword(s):  
Maldi Ms ◽  
Reactive Matrix ◽  
Selective Analysis

scholarly journals Recyclable Nanoparticles Based on Boronic Acid-Diol Complex for Real-Time Monitoring of Imprinting, Molecular Recognition and Detection of Copper Ion

2021 ◽  
Author(s):  
Xiaoting Xue ◽  
Man Zhang ◽  
Haiyue Gong ◽  
Lei Ye
Keyword(s):  
Molecular Recognition ◽  
Real Time ◽  
Molecularly Imprinted Polymers ◽  
Boronic Acid ◽  
Copper Ion ◽  
Real Time Monitoring ◽  
Molecularly Imprinted ◽  
Imprinted Polymers

Molecularly imprinted polymers (MIPs) have now become one of the most remarkable materials in the field of molecular recognition. Although many efforts have been made to study the process and...

Arylboronic Acids in Self-condensation of Glucosamines Forming Deoxyfructosazine, Catalysts or Reagents?

2019 ◽  
Author(s):  
Meifeng Wang ◽  
Gan Zhu ◽  
Yiqun Li ◽  
Liuqun Gu
Keyword(s):  
Molecular Recognition ◽  
Boric Acid ◽  
Boronic Acid ◽  
Catalytic Mechanism ◽  
Organic Transformations ◽  
Food Industries ◽  
Arylboronic Acids ◽  
Excess Amount ◽  
Phenyl Boronic Acid ◽  
Boron Acid

Arylboronic acids were widely used as efficient catalysts in direct amide formation and other organic transformations. Surprisingly, reports on their use as catalysts in carbohydrates synthesis are very rare even though boron acid-diol complexation was extensively investigated in molecular recognition for saccharides and so on. Here we developed an efficient arylboronic acids catalyzed dimerization of glucosamines forming deoxyfructosazine which is important compound in pharmaceutical and food industries, against a commonly held belief that excess amount of phenyl boronic acid (or boric acid) is a must. A catalytic mechanism was also proposed and arylboronic acids instead of their boronates was identified as catalysts.

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