scholarly journals Recyclable Nanoparticles Based on Boronic Acid-Diol Complex for Real-Time Monitoring of Imprinting, Molecular Recognition and Detection of Copper Ion

Author(s):  
Xiaoting Xue ◽  
Man Zhang ◽  
Haiyue Gong ◽  
Lei Ye

Molecularly imprinted polymers (MIPs) have now become one of the most remarkable materials in the field of molecular recognition. Although many efforts have been made to study the process and...

Sensors ◽  
2021 ◽  
Vol 21 (8) ◽  
pp. 2757
Author(s):  
W. Rudolf Seitz ◽  
Casey J. Grenier ◽  
John R. Csoros ◽  
Rongfang Yang ◽  
Tianyu Ren

This perspective presents an overview of approaches to the preparation of molecular recognition agents for chemical sensing. These approaches include chemical synthesis, using catalysts from biological systems, partitioning, aptamers, antibodies and molecularly imprinted polymers. The latter three approaches are general in that they can be applied with a large number of analytes, both proteins and smaller molecules like drugs and hormones. Aptamers and antibodies bind analytes rapidly while molecularly imprinted polymers bind much more slowly. Most molecularly imprinted polymers, formed by polymerizing in the presence of a template, contain a high level of covalent crosslinker that causes the polymer to form a separate phase. This results in a material that is rigid with low affinity for analyte and slow binding kinetics. Our approach to templating is to use predominantly or exclusively noncovalent crosslinks. This results in soluble templated polymers that bind analyte rapidly with high affinity. The biggest challenge of this approach is that the chains are tangled when the templated polymer is dissolved in water, blocking access to binding sites.


2005 ◽  
Vol 5 (5) ◽  
pp. 263-275 ◽  
Author(s):  
Toshifumi Takeuchi ◽  
Takashi Mukawa ◽  
Hideyuki Shinmori

The Analyst ◽  
2019 ◽  
Vol 144 (21) ◽  
pp. 6432-6437 ◽  
Author(s):  
Yanli Zhou ◽  
Huijie Huangfu ◽  
Jie Yang ◽  
Hui Dong ◽  
Lantao liu ◽  
...  

A potentiometric sensor for sialic acid detection was designed based on a boronic acid-containing MIP modified carbon cloth electrode.


2021 ◽  
Author(s):  
Mingwei Wang ◽  
Fengxia Qiao ◽  
Hongyuan Yan

Molecularly imprinted polymers (MIPs) are conventionally synthesized in organic solvents, resulting in poor compatibility with water and weak molecular recognition of targets in aqueous environments; hence, developing a green process...


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