Size-dependent biodistribution and antitumor efficacy of polymer micelle drug delivery systems

2013 ◽  
Vol 1 (34) ◽  
pp. 4273 ◽  
Author(s):  
Jun Yue ◽  
Shi Liu ◽  
Zhigang Xie ◽  
Ying Xing ◽  
Xiabin Jing
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Antitumor Efficacy ◽  
Polymer Micelle ◽  
Size Dependent

The influence of trapping agents on the antitumor efficacy of irinotecan liposomes: head-to-head comparison of ammonium sulfate, sulfobutylether-β-cyclodextrin and sucrose octasulfate

2019 ◽  
Vol 7 (1) ◽  
pp. 419-428 ◽  
Author(s):  
Wenqian Yang ◽  
Zimeng Yang ◽  
Jingru Fu ◽  
Mengran Guo ◽  
Bingjun Sun ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Ammonium Sulfate ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Antitumor Efficacy ◽  
Outstanding Achievement ◽  
Sucrose Octasulfate ◽  
Remote Loading

Remote loading technology is an outstanding achievement in liposome-based drug delivery systems.

scholarly journals Applications of Noble Metal-Based Nanoparticles in Medicine

2018 ◽  
Vol 19 (12) ◽  
pp. 4031 ◽  
Author(s):  
Bartosz Klębowski ◽  
Joanna Depciuch ◽  
Magdalena Parlińska-Wojtan ◽  
Jarek Baran
Keyword(s):  
Drug Delivery ◽  
Noble Metal ◽  
Proton Therapy ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Therapeutic Modalities ◽  
Size Dependent

Nanoparticles have unique, size-dependent properties, which means they are widely used in various branches of industry. The ability to control the properties of nanoparticles makes these nanomaterials very interesting for medicine and pharmacology. The application of nanoparticles in medicine is associated with the design of specific nanostructures, which can be used as novel diagnostic and therapeutic modalities. There are a lot of applications of nanoparticles, e.g., as drug delivery systems, radiosensitizers in radiation or proton therapy, in bioimaging, or as bactericides/fungicides. This paper aims to introduce the characteristics of noble metal-based nanoparticles with particular emphasis on their applications in medicine and related sciences.

scholarly journals Solid Lipid Nanoparticles: Emerging Colloidal Nano Drug Delivery Systems

Pharmaceutics ◽  
2018 ◽  
Vol 10 (4) ◽  
pp. 191 ◽  
Author(s):  
Vijay Mishra ◽  
Kuldeep Bansal ◽  
Asit Verma ◽  
Nishika Yadav ◽  
Sourav Thakur ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Solid Lipid Nanoparticles ◽  
Drug Delivery Systems ◽  
Polymeric Nanoparticles ◽  
Lipid Nanoparticles ◽  
Delivery Systems ◽  
Routes Of Administration ◽  
Size Dependent ◽  
Solid Lipid ◽  
Nano Drug Delivery

Solid lipid nanoparticles (SLNs) are nanocarriers developed as substitute colloidal drug delivery systems parallel to liposomes, lipid emulsions, polymeric nanoparticles, and so forth. Owing to their unique size dependent properties and ability to incorporate drugs, SLNs present an opportunity to build up new therapeutic prototypes for drug delivery and targeting. SLNs hold great potential for attaining the goal of targeted and controlled drug delivery, which currently draws the interest of researchers worldwide. The present review sheds light on different aspects of SLNs including fabrication and characterization techniques, formulation variables, routes of administration, surface modifications, toxicity, and biomedical applications.

Size-Dependent Regulation of Intracellular Trafficking of Polystyrene Nanoparticle-Based Drug-Delivery Systems

2017 ◽  
Vol 9 (22) ◽  
pp. 18619-18625 ◽  
Author(s):  
Ting Wang ◽  
Lu Wang ◽  
Xiaoming Li ◽  
Xingjie Hu ◽  
Yuping Han ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Intracellular Trafficking ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Size Dependent

Techniques For The Preparation of Tissue Samples Containing Injectable Polymer Microcapsules

1985 ◽  
Vol 43 ◽  
pp. 710-711
Author(s):  
G.E. Visscher ◽  
R. L. Robison ◽  
G. J. Argentieri
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Gastrocnemius Muscle ◽  
Degradation Process ◽  
Delivery Systems ◽  
Tissue Reaction ◽  
Electron Microscopic ◽  
Tissue Samples ◽  
Injectable Polymer ◽  
Microscopic Techniques

The use of various bioerodable polymers as drug delivery systems has gained considerable interest in recent years. Among some of the shapes used as delivery systems are films, rods and microcapsules. The work presented here will deal with the techniques we have utilized for the analysis of the tissue reaction to and actual biodegradation of injectable microcapsules. This work has utilized light microscopic (LM), transmission (TEM) and scanning (SEM) electron microscopic techniques. The design of our studies has utilized methodology that would; 1. best characterize the actual degradation process without artifacts introduced by fixation procedures and 2. allow for reproducible results.In our studies, the gastrocnemius muscle of the rat was chosen as the injection site. Prior to the injection of microcapsules the skin above the sites was shaved and tattooed for later recognition and recovery. 1.0 cc syringes were loaded with the desired quantity of microcapsules and the vehicle (0.5% hydroxypropylmethycellulose) drawn up. The syringes were agitated to suspend the microcapsules in the injection vehicle.

Sign in / Sign up

Export Citation Format

Share Document