A mechanistic study supports a two-step mechanism for peptide bond formation on the ribosome

2013 ◽  
Vol 15 (36) ◽  
pp. 14931 ◽  
Author(s):  
Byung Jin Byun ◽  
Young Kee Kang
Keyword(s):  
Bond Formation ◽  
Peptide Bond ◽  
Mechanistic Study ◽  
Peptide Bond Formation ◽  
Step Mechanism

Beyond peptide bond formation: the versatile role of condensation domains in natural product biosynthesis

2021 ◽  
Author(s):  
Sofie Dekimpe ◽  
Joleen Masschelein
Keyword(s):  
Natural Product ◽  
Bond Formation ◽  
Peptide Bond ◽  
Chemical Diversity ◽  
Peptide Bond Formation ◽  
Natural Product Biosynthesis

Condensation domains perform highly diverse functions during natural product biosynthesis and are capable of generating remarkable chemical diversity.

scholarly journals En Route to a Heterogeneous Catalytic Direct Peptide Bond Formation by Zr-Based Metal–Organic Framework Catalysts

ACS Catalysis ◽  
2021 ◽  
pp. 7647-7658
Author(s):  
Francisco de Azambuja ◽  
Alexandra Loosen ◽  
Dragan Conic ◽  
Maxime van den Besselaar ◽  
Jeremy N. Harvey ◽  
...  
Keyword(s):  
Metal Organic Framework ◽  
Bond Formation ◽  
Peptide Bond ◽  
Peptide Bond Formation ◽  
Heterogeneous Catalytic ◽  
Metal Organic ◽  
Organic Framework

Oxidative Peptide Bond Formation of Glycine-Amino Acid using 2-(Aminomethyl)malononitrile as a Glycine Unit

2021 ◽  
Author(s):  
Xiaoling Wang ◽  
Jing Li ◽  
Yujiro Hayashi
Keyword(s):  
Aqueous Solution ◽  
Amino Acid ◽  
Bond Formation ◽  
Peptide Bond ◽  
Peptide Bond Formation ◽  
Amide Linkage

Amide linkage of glycine-amino acid was synthesized by coupling of substituted 2-(aminomethyl)malononitrile as a C-terminal glycine unit and N-terminal amine using CsOAc and O2 in aqueous solution. This is a...

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