scholarly journals En Route to a Heterogeneous Catalytic Direct Peptide Bond Formation by Zr-Based Metal–Organic Framework Catalysts

ACS Catalysis ◽  
2021 ◽  
pp. 7647-7658
Author(s):  
Francisco de Azambuja ◽  
Alexandra Loosen ◽  
Dragan Conic ◽  
Maxime van den Besselaar ◽  
Jeremy N. Harvey ◽  
...  
Keyword(s):  
Metal Organic Framework ◽  
Bond Formation ◽  
Peptide Bond ◽  
Peptide Bond Formation ◽  
Heterogeneous Catalytic ◽  
Metal Organic ◽  
Organic Framework

scholarly journals A Zirconium Metal-Organic Framework with SOC Topological Net for Catalytic Peptide Bond Hydrolysis

2021 ◽  
Author(s):  
Sujing Wang ◽  
Antoine Tissot ◽  
Guillaume Maurin ◽  
Tatjana Parac-Vogt ◽  
Christian Serre ◽  
...  
Keyword(s):  
Active Sites ◽  
Metal Organic Framework ◽  
Cost Effective ◽  
Peptide Bond ◽  
Catalytic Performance ◽  
Wide Range ◽  
Horse Heart Myoglobin ◽  
Metal Organic ◽  
Effective Synthesis ◽  
Organic Framework

<div>The discovery of nanozymes for selective cleavage of proteins would boost the emerging areas of modern proteomics, however, the development of efficient and reusable artificial catalysts for peptide bond hydrolysis is challenging. Here we report the detailed catalytic properties of a microporous zirconium carboxylate metal-organic framework, MIP-201, in promoting peptide bond hydrolysis in a simple dipeptide, as well as in horse-heart myoglobin (Mb) protein that consists of 153 amino acids. We demonstrate that MIP-201 features an excellent catalytic activity and selectivity, a good tolerance toward reaction conditions covering a wide range of different pH values, and importantly, an exceptional recycling ability associated with easy regeneration process. Taking into account the excellent catalytic performance of MIP-201 and its other advantages such as 6-connected Zr6 cluster active sites, the green, scalable and cost-effective synthesis, and an outstanding chemical and architectural stability, our finding suggests that MIP-201 may be a promising and practical alternative to the current commercially available catalysts for peptide bond hydrolysis.</div>

scholarly journals A Zirconium Metal-Organic Framework with SOC Topological Net for Catalytic Peptide Bond Hydrolysis

2021 ◽  
Author(s):  
Sujing Wang ◽  
Antoine Tissot ◽  
Guillaume Maurin ◽  
Tatjana Parac-Vogt ◽  
Christian Serre ◽  
...  
Keyword(s):  
Active Sites ◽  
Metal Organic Framework ◽  
Cost Effective ◽  
Peptide Bond ◽  
Catalytic Performance ◽  
Wide Range ◽  
Horse Heart Myoglobin ◽  
Metal Organic ◽  
Effective Synthesis ◽  
Organic Framework

<div>The discovery of nanozymes for selective cleavage of proteins would boost the emerging areas of modern proteomics, however, the development of efficient and reusable artificial catalysts for peptide bond hydrolysis is challenging. Here we report the detailed catalytic properties of a microporous zirconium carboxylate metal-organic framework, MIP-201, in promoting peptide bond hydrolysis in a simple dipeptide, as well as in horse-heart myoglobin (Mb) protein that consists of 153 amino acids. We demonstrate that MIP-201 features an excellent catalytic activity and selectivity, a good tolerance toward reaction conditions covering a wide range of different pH values, and importantly, an exceptional recycling ability associated with easy regeneration process. Taking into account the excellent catalytic performance of MIP-201 and its other advantages such as 6-connected Zr6 cluster active sites, the green, scalable and cost-effective synthesis, and an outstanding chemical and architectural stability, our finding suggests that MIP-201 may be a promising and practical alternative to the current commercially available catalysts for peptide bond hydrolysis.</div>

A Stable Porphyrin-Based Porous mog Metal–Organic Framework as an Efficient Solvent-Free Catalyst for C–C Bond Formation

2017 ◽  
Vol 56 (5) ◽  
pp. 3036-3043 ◽  
Author(s):  
Wei Jiang ◽  
Jin Yang ◽  
Ying-Ying Liu ◽  
Shu-Yan Song ◽  
Jian-Fang Ma
Keyword(s):  
Metal Organic Framework ◽  
Bond Formation ◽  
Solvent Free ◽  
Metal Organic ◽  
Organic Framework

Chiral Co(II) Metal–Organic Framework in the Heterogeneous Catalytic Oxidation of Alkenes under Aerobic and Anaerobic Conditions

ACS Catalysis ◽  
2014 ◽  
Vol 4 (3) ◽  
pp. 1032-1039 ◽  
Author(s):  
Giulia Tuci ◽  
Giuliano Giambastiani ◽  
Stephanie Kwon ◽  
Peter C. Stair ◽  
Randall Q. Snurr ◽  
...  
Keyword(s):  
Catalytic Oxidation ◽  
Metal Organic Framework ◽  
Anaerobic Conditions ◽  
Heterogeneous Catalytic ◽  
Metal Organic ◽  
Aerobic And Anaerobic ◽  
Aerobic And Anaerobic Conditions ◽  
Organic Framework

scholarly journals Palladium nanoparticles supported on a nickel pyrazolate metal organic framework as a catalyst for Suzuki and carbonylative Suzuki couplings

2016 ◽  
Vol 45 (34) ◽  
pp. 13525-13531 ◽  
Author(s):  
A. W. Augustyniak ◽  
W. Zawartka ◽  
J. A. R. Navarro ◽  
A. M. Trzeciak
Keyword(s):  
Palladium Nanoparticles ◽  
Metal Organic Framework ◽  
Catalytic Activities ◽  
Heterogeneous Catalytic ◽  
Metal Organic ◽  
Organic Framework

Methanolic reduction of [PdCl2(CH3CN)2] on a [Ni(2,5-di(1H-pyrazol-4-yl)benzenesulfonate)2] metal organic framework gives rise to Pd2+/Pd0 nanocomposites with Suzuki and carbonylative Suzuki heterogeneous catalytic activities.

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