CuII-mediated controllable creation of tertiary and quaternary carbon centers: designed assembly and structures of a new class of copper complexes supported by in situ generated substituted 1-pyridineimidazo[1,5-a]pyridine ligands

CrystEngComm ◽  
2013 ◽  
Vol 15 (14) ◽  
pp. 2675 ◽  
Author(s):  
Yanmei Chen ◽  
Lei Li ◽  
Yanyuan Cao ◽  
Jian Wu ◽  
Qian Gao ◽  
...  
Keyword(s):  
Copper Complexes ◽  
Quaternary Carbon ◽  
Carbon Centers ◽  
New Class ◽  
Pyridine Ligands ◽  
Substituted 1

The Catalytic Asymmetric Dearomatization of Tryptamine for Accessing meso-Contiguous Quaternary Carbon Centers of Oligomeric Cyclotryptamine Alkaloids: a Formal Synthesis of Hodgkinsine B

2021 ◽  
Author(s):  
Hongbo Wei ◽  
Guzhou Chen ◽  
Huanhuan Zou ◽  
Zhiqiang Zhou ◽  
Pan Lei ◽  
...  
Keyword(s):  
Quaternary Carbon ◽  
Formal Synthesis ◽  
Carbon Centers ◽  
Catalytic Asymmetric

Herein, we disclosed a catalytic asymmetric dearomatization (CADA) of tryptamine via tandem [4+2] cycloaddition/cyclization with o-azaxylylene in situ generated from functionalized 3-bromooxinidole promoted by chiral N,N’-dioxide/Ni(BF4)2. A variety of dimeric...

Asymmetric Construction of Quaternary Carbon Centers by Sequential Conjugate Addition of Lithium Amide and in Situ Alkylation: Utility in the Synthesis of (−)-Aspidospermidine

2009 ◽  
Vol 11 (3) ◽  
pp. 653-655 ◽  
Author(s):  
Mayuko Suzuki ◽  
Yoshito Kawamoto ◽  
Takeo Sakai ◽  
Yasutomo Yamamoto ◽  
Kiyoshi Tomioka
Keyword(s):  
Conjugate Addition ◽  
Quaternary Carbon ◽  
Lithium Amide ◽  
Carbon Centers

Synthesis, characterization and biological activities of 1,3,4-oxadiazole derivatives of nalidixic acid and their copper complexes

2019 ◽  
Author(s):  
Chem Int
Keyword(s):  
Nalidixic Acid ◽  
Copper Complexes ◽  
Biological Activities ◽  
Bidentate Coordination ◽  
Antibacterial And Antifungal Activities ◽  
Elemental Analyses ◽  
Oxadiazole Derivatives ◽  
Antibacterial And Antifungal ◽  
Derivatives Of ◽  
Substituted 1

A series of novel 1, 3, 4-oxadiazole analogues was synthesized from cyclization of hydrazones of substituted 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carbohydrazides were prepared from nalidixic acid. The structures of synthesized oxadiazole derivatives and their copper complexes were elucidated on the basis of FTIR, elemental analyses, 1H-NMR and atomic absorption spectral analysis. It was observed from spectral data that metal ligand ratio was 1:1 in all copper complexes and they were bidentate, coordination was found to be done through oxygen of 4-oxo group and nitrogen of oxadiazole ring. The synthesized compounds were further evaluated with biological activities and compared with parent hydrazones. Copper complexes possess antibacterial and antifungal activities better than the oxadiazoles while they have better antioxidant activity then copper complexes. Parent hydrazones were better in all biological activities than synthesized oxadiazoles.

Stereocontrolled Synthesis of Highly Functionalized Quaternary Carbon Centers: A Route to α-Substituted Serines

2009 ◽  
Vol 121 (23) ◽  
pp. 4266-4269 ◽  
Author(s):  
Xavier Ariza ◽  
Josep Cornellà ◽  
Mercè Font-Bardia ◽  
Jordi Garcia ◽  
Jordi Ortiz ◽  
...  
Keyword(s):  
Quaternary Carbon ◽  
Carbon Centers ◽  
Stereocontrolled Synthesis
Sign in / Sign up

Export Citation Format

Share Document