Synthesis of Janus particles via kinetic control of phase separation in emulsion droplets

2013 ◽  
Vol 49 (84) ◽  
pp. 9746 ◽  
Author(s):  
Bing Liu ◽  
Helmuth Möhwald ◽  
Dayang Wang
Keyword(s):  
Phase Separation ◽  
Janus Particles ◽  
Kinetic Control ◽  
Emulsion Droplets

scholarly journals Fabrication of Multi-Layered Microspheres Based on Phase Separation for Drug Delivery

Micromachines ◽  
2021 ◽  
Vol 12 (6) ◽  
pp. 723
Author(s):  
He Xia ◽  
Ang Li ◽  
Jia Man ◽  
Jianyong Li ◽  
Jianfeng Li
Keyword(s):  
Aqueous Solution ◽  
Phase Separation ◽  
Gastric Fluid ◽  
Simulated Gastric Fluid ◽  
Sustained Drug Release ◽  
Simulated Intestinal Fluid ◽  
Glycol Diacrylate ◽  
Emulsion Droplets ◽  
Collection Tube ◽  
Poly Ethylene

In this work, we used a co-flow microfluidic device with an injection and a collection tube to generate droplets with different layers due to phase separation. The phase separation system consisted of poly(ethylene glycol) diacrylate 700 (PEGDA 700), PEGDA 250, and sodium alginate aqueous solution. When the mixture droplets formed in the outer phase, PEGDA 700 in the droplets would transfer into the outer aqueous solution, while PEGDA 250 still stayed in the initial droplet, breaking the miscibility equilibrium of the mixture and triggering the phase separation. As the phase separation proceeded, new cores emerged in the droplets, gradually forming the second and third layers. Emulsion droplets with different layers were polymerized under ultraviolet (UV) irradiation at different stages of phase separation to obtain microspheres. Microspheres with different layers showed various release behaviors in simulated gastric fluid (SGF) and simulated intestinal fluid (SIF). The release rate decreased with the increase in the number of layers, which showed a potential application in sustained drug release.

Size-Dependent Phase Separation in Emulsion Droplets

ChemPhysChem ◽  
2018 ◽  
Vol 19 (16) ◽  
pp. 1995-1998 ◽  
Author(s):  
Jia Man ◽  
Steven Chien ◽  
Shuaishuai Liang ◽  
Jiang Li ◽  
Haosheng Chen
Keyword(s):  
Phase Separation ◽  
Size Dependent ◽  
Emulsion Droplets

One-step fabrication of polymeric hybrid particles with core–shell, patchy, patchy Janus and Janus architectures via a microfluidic-assisted phase separation process

RSC Advances ◽  
2015 ◽  
Vol 5 (97) ◽  
pp. 79969-79975 ◽  
Author(s):  
Xiaodong Cao ◽  
Wenxiu Li ◽  
Ting Ma ◽  
Hua Dong
Keyword(s):  
Phase Separation ◽  
Separation Process ◽  
Janus Particles ◽  
Core Shell ◽  
Hybrid Particles ◽  
Phase Separation Process ◽  
One Step

We report in this paper a one-step route for the preparation of core–shell, patchy, patchy Janus and Janus particles via a microfluidic-assisted phase separation process.

Microfluidic synthesis of Janus particles by UV-directed phase separation

2011 ◽  
Vol 47 (9) ◽  
pp. 2634 ◽  
Author(s):  
Saifullah Lone ◽  
Sung Hoon Kim ◽  
Seong Won Nam ◽  
Sungsu Park ◽  
Jin Joo ◽  
...  
Keyword(s):  
Phase Separation ◽  
Janus Particles

scholarly journals Flow-induced phase separation of active particles is controlled by boundary conditions

2018 ◽  
Vol 115 (21) ◽  
pp. 5403-5408 ◽  
Author(s):  
Shashi Thutupalli ◽  
Delphine Geyer ◽  
Rajesh Singh ◽  
Ronojoy Adhikari ◽  
Howard A. Stone
Keyword(s):  
Phase Separation ◽  
Boundary Conditions ◽  
Numerical Simulations ◽  
Colloidal Suspensions ◽  
Many Body ◽  
Ordered Structures ◽  
Emulsion Droplets ◽  
Cell Height ◽  
Active Particles ◽  
Out Of Plane

Active particles, including swimming microorganisms, autophoretic colloids, and droplets, are known to self-organize into ordered structures at fluid–solid boundaries. The entrainment of particles in the attractive parts of their spontaneous flows has been postulated as a possible mechanism underlying this phenomenon. Here, combining experiments, theory, and numerical simulations, we demonstrate the validity of this flow-induced ordering mechanism in a suspension of active emulsion droplets. We show that the mechanism can be controlled, with a variety of resultant ordered structures, by simply altering hydrodynamic boundary conditions. Thus, for flow in Hele–Shaw cells, metastable lines or stable traveling bands can be obtained by varying the cell height. Similarly, for flow bounded by a plane, dynamic crystallites are formed. At a no-slip wall, the crystallites are characterized by a continuous out-of-plane flux of particles that circulate and re-enter at the crystallite edges, thereby stabilizing them. At an interface where the tangential stress vanishes, the crystallites are strictly 2D, with no out-of-plane flux. We rationalize these experimental results by calculating, in each case, the slow viscous flow produced by the droplets and the long-ranged, many-body active forces and torques between them. The results of numerical simulations of motion under the action of the active forces and torques are in excellent agreement with experiments. Our work elucidates the mechanism of flow-induced phase separation in active fluids, particularly active colloidal suspensions, and demonstrates its control by boundaries, suggesting routes to geometric and topological phenomena in an active matter.

Facile fabrication of Fe3O4@PS/PGMA magnetic Janus particles via organic–inorganic dual phase separation

RSC Advances ◽  
2014 ◽  
Vol 4 (52) ◽  
pp. 27152 ◽  
Author(s):  
Lei Tian ◽  
Baoliang Zhang ◽  
Wei Li ◽  
Xiangjie Li ◽  
Xinlong Fan ◽  
...  
Keyword(s):  
Phase Separation ◽  
Janus Particles ◽  
Dual Phase ◽  
Facile Fabrication

Janus Particles Templated from Double Emulsion Droplets Generated Using Microfluidics

Langmuir ◽  
2009 ◽  
Vol 25 (8) ◽  
pp. 4320-4323 ◽  
Author(s):  
Chia-Hung Chen ◽  
Rhutesh K. Shah ◽  
Adam R. Abate ◽  
David A. Weitz
Keyword(s):  
Double Emulsion ◽  
Janus Particles ◽  
Emulsion Droplets ◽  
Double Emulsion Droplets
Sign in / Sign up

Export Citation Format

Share Document