scholarly journals Multilayered nanocoatings incorporating superparamagnetic nanoparticles for tracking of pancreatic islet transplants with magnetic resonance imaging

2013 ◽  
Vol 49 (65) ◽  
pp. 7255 ◽  
Author(s):  
Yang Wang ◽  
Cristina Blanco-Andujar ◽  
Zheng-liang Zhi ◽  
Po-Wah So ◽  
Nguyen Thi Kim Thanh ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Pancreatic Islet ◽  
Superparamagnetic Nanoparticles ◽  
Resonance Imaging ◽  
Islet Transplants

FULVIC ACID COATED IRON OXIDE NANOPARTICLES FOR MAGNETIC RESONANCE IMAGING CONTRAST AGENT

2010 ◽  
Vol 03 (03) ◽  
pp. 197-200 ◽  
Author(s):  
CHUNJIAO ZHOU ◽  
PENGFEI RONG ◽  
WENJIE ZHANG ◽  
JIANDA ZHOU ◽  
QINGLIN ZHANG ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agent ◽  
Fulvic Acid ◽  
Superparamagnetic Nanoparticles ◽  
Mri Contrast Agent ◽  
Hydroxyl Groups ◽  
Resonance Imaging ◽  
Magnetic Resonance Imaging Contrast ◽  
Magnetic Resonance Imaging Mri

Fulvic acid coated Fe 3 O 4 superparamagnetic nanoparticles were synthesized by a coprecipitation technique with iron salts and a small molecule stabilizer-fulvic acid. The prepared nanoparticles were well dispersed in water with about 10 nm in size according to transmission electron microscopy (TEM) observations. Fourier transform infrared spectroscopy (FTIR) revealed that fulvic acid were successfully covalently bonded to Fe 3 O 4 through the two adjacent phenolic hydroxyl groups and the carboxyl (- COOH ) groups were functionalized to the surface. The vibrating sample magnetometer (VSM) result showed that the nanoparticles were superparamagnetic and the saturation magnetizations were 60 emu/g. Moreover, their efficacy of liver magnetic resonance imaging (MRI) contrast agent was investigated by using live rat and tumor-bearing rabbit models through conventional clinical 1.5T MRI.

Controlled Clustering of Superparamagnetic Nanoparticles Using Block Copolymers: Design of New Contrast Agents for Magnetic Resonance Imaging

2006 ◽  
Vol 128 (5) ◽  
pp. 1755-1761 ◽  
Author(s):  
Jean-François Berret ◽  
Nicolas Schonbeck ◽  
Florence Gazeau ◽  
Delphine El Kharrat ◽  
Olivier Sandre ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Block Copolymers ◽  
Contrast Agents ◽  
Superparamagnetic Nanoparticles ◽  
Resonance Imaging

scholarly journals Development of New Contrast Agents for Imaging Function and Metabolism by Magnetic Resonance Imaging

2017 ◽  
Vol 10 ◽  
pp. 1178623X1772213 ◽  
Author(s):  
Alexandra Carvalho ◽  
M Clara Gonçalves ◽  
M Luísa Corvo ◽  
M Bárbara F Martins
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Magnetic Particles ◽  
Superparamagnetic Iron Oxide ◽  
Medical Application ◽  
Magnetic Resonance Images ◽  
Superparamagnetic Nanoparticles ◽  
Resonance Imaging ◽  
Wide Range

Liposomes are interesting nanosystems with a wide range of medical application. One particular application is their ability to enhance contrast in magnetic resonance images; when properly loaded with magnetic/superparamagnetic nanoparticles, this means to act as contrast agents. The design of liposomes loaded with magnetic particles, magnetoliposomes, presents a large number of possibilities depending on the application from image function to metabolism. More interesting is its double function application as theranostics (diagnostics and therapy). The synthesis, characterization, and possible medical applications of two types of magnetoliposomes are reviewed. Their performance will be compared, in particular, their efficiency as contrast agents for magnetic resonance imaging, measured by their relaxivities r1 and r2 relating to their particular composition. One of the magnetoliposomes had 1,2-diacyl-sn-glycero-3-phosphocholine (soy) as the main phospholipid component, with and without cholesterol, varying its phospholipid to cholesterol molar ratios. The other formulation is a long-circulating liposome composed of 1,2-diacyl-sn-glycero-3-phosphocholine (egg), cholesterol, and 1,2-distearoyl-sn-glycerol-3-phosphoethanolamine- N-[methoxy(polyethylene glycol)-2000]. Both nanosystems were loaded with superparamagnetic iron oxide nanoparticles with different sizes and coatings.

scholarly journals Superparamagnetic Nanoparticles as High Efficiency Magnetic Resonance Imaging T2 Contrast Agent

2016 ◽  
Vol 28 (1) ◽  
pp. 161-170 ◽  
Author(s):  
Fernanda Sousa ◽  
Barbara Sanavio ◽  
Alessandra Saccani ◽  
Yun Tang ◽  
Ileana Zucca ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agent ◽  
High Efficiency ◽  
Superparamagnetic Nanoparticles ◽  
Resonance Imaging

Uptake and bioreactivity of charged chitosan-coated superparamagnetic nanoparticles as promising contrast agents for magnetic resonance imaging

2018 ◽  
Vol 14 (1) ◽  
pp. 131-140 ◽  
Author(s):  
Gabriela Kania ◽  
Magdalena Sternak ◽  
Agnieszka Jasztal ◽  
Stefan Chlopicki ◽  
Agnieszka Błażejczyk ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Superparamagnetic Nanoparticles ◽  
Resonance Imaging
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