scholarly journals Design of core–shell gold‐coated superparamagnetic nanoparticles as a theranostic for targeted magnetic resonance imaging and photoablation therapy

2019 ◽  
Vol 14 (11) ◽  
pp. 1187-1191 ◽  
Author(s):  
Daniel Goldstein ◽  
Chendong Han ◽  
Matthew Mahan ◽  
Amber Doiron
2021 ◽  
Vol 20 ◽  
pp. 153303382110365
Author(s):  
Lin Qiu ◽  
Shuwen Zhou ◽  
Ying Li ◽  
Wen Rui ◽  
Pengfei Cui ◽  
...  

Bifunctional magnetic/fluorescent core-shell silica nanospheres (MNPs) encapsulated with the magnetic Fe3O4 core and a derivate of 8-amimoquinoline (N-(quinolin-8-yl)-2-(3-(triethoxysilyl) propylamino) acetamide) (QTEPA) into the shell were synthesized. These functional MNPs were prepared with a modified stöber method and the formed Fe3O4@SiO2-QTEPA core-shell nanocomposites are biocompatible, water-dispersible, and stable. These prepared nanoparticles were characterized by X-ray power diffraction (XRD), transmission electron microscopy (TEM), thermoelectric plasma Quad II inductively coupled plasma mass spectrometry (ICP-MS), superconducting quantum interference device (SQUID), TG/DTA thermal analyzer (TGA) and Fourier transform infrared spectroscopy (FTIR). Further application of the nanoparticles in detecting Zn2+ was confirmed by the fluorescence experiment: the nanosensor shows high selectivity and sensitivity to Zn2+ with a 22-fold fluorescence emission enhancement in the presence of 10 μM Zn2+. Moreover, the transverse relaxivity measurements show that the core-shell MNPs have T2 relaxivity (r2) of 155.05 mM−1 S−1 based on Fe concentration on the 3.0 T scanner, suggesting that the compound can be used as a negative contrast agent for MRI. Further in vivo experiments showed that these MNPs could be used as MRI contrast agent. Therefore, the new nanosensor provides the dual modality of magnetic resonance imaging and optical imaging.


RSC Advances ◽  
2018 ◽  
Vol 8 (47) ◽  
pp. 26764-26770 ◽  
Author(s):  
Kaili Wang ◽  
Lu An ◽  
Qiwei Tian ◽  
Jiaomin Lin ◽  
Shiping Yang

Magnetic resonance imaging (MRI) is indispensable and powerful in modern clinical diagnosis and has some advantages such as non-invasiveness and high penetration depth.


RSC Advances ◽  
2016 ◽  
Vol 6 (23) ◽  
pp. 18843-18851 ◽  
Author(s):  
N. Venkatesha ◽  
Yasrib Qurishi ◽  
Hanudatta S. Atreya ◽  
Chandan Srivastava

The potential of CoFe2O4–ZnO core–shell nanoparticles for fluorescence optical imaging and as a contrast agent for magnetic resonance imaging (MRI) is demonstrated.


2019 ◽  
Vol 58 (24) ◽  
pp. 16618-16628 ◽  
Author(s):  
Sonia L. C. Pinho ◽  
José Sereno ◽  
Antero J. Abrunhosa ◽  
Marie-Hélène Delville ◽  
João Rocha ◽  
...  

Biomaterials ◽  
2010 ◽  
Vol 31 (6) ◽  
pp. 1316-1324 ◽  
Author(s):  
Po-Wei Lee ◽  
Sheng-Hsiang Hsu ◽  
Jiun-Jie Wang ◽  
Jin-Sheng Tsai ◽  
Kun-Ju Lin ◽  
...  

2010 ◽  
Vol 03 (03) ◽  
pp. 197-200 ◽  
Author(s):  
CHUNJIAO ZHOU ◽  
PENGFEI RONG ◽  
WENJIE ZHANG ◽  
JIANDA ZHOU ◽  
QINGLIN ZHANG ◽  
...  

Fulvic acid coated Fe 3 O 4 superparamagnetic nanoparticles were synthesized by a coprecipitation technique with iron salts and a small molecule stabilizer-fulvic acid. The prepared nanoparticles were well dispersed in water with about 10 nm in size according to transmission electron microscopy (TEM) observations. Fourier transform infrared spectroscopy (FTIR) revealed that fulvic acid were successfully covalently bonded to Fe 3 O 4 through the two adjacent phenolic hydroxyl groups and the carboxyl (- COOH ) groups were functionalized to the surface. The vibrating sample magnetometer (VSM) result showed that the nanoparticles were superparamagnetic and the saturation magnetizations were 60 emu/g. Moreover, their efficacy of liver magnetic resonance imaging (MRI) contrast agent was investigated by using live rat and tumor-bearing rabbit models through conventional clinical 1.5T MRI.


Nanoscale ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 1801-1810 ◽  
Author(s):  
Yang Gao ◽  
Luyun Zhang ◽  
Yanhong Liu ◽  
Sijia Sun ◽  
Zhibin Yin ◽  
...  

Ce6/Mn2+-chelated, polydopamine (PDA)-coated black TiO2 (b-P25@PDA-Ce6 (Mn)) nanoprobes with core–shell structure were constructed for enhanced synergistic phototherapy and magnetic resonance (MR) imaging.


2018 ◽  
Vol 54 (68) ◽  
pp. 9525-9528 ◽  
Author(s):  
Feiya Xu ◽  
Yiming Zhao ◽  
Min Hu ◽  
Pu Zhang ◽  
Ning Kong ◽  
...  

We report a novel lanthanide-doped core–shell nanostructure NaYF4:Yb,Er@NaGdF4:Nd@SiO2-RB with a unique design feature that integrates luminescence imaging in biological window II, magnetic resonance imaging, and NIR-excited photodynamic antimicrobial chemotherapy, in a single nanoscale entity.


2006 ◽  
Vol 128 (5) ◽  
pp. 1755-1761 ◽  
Author(s):  
Jean-François Berret ◽  
Nicolas Schonbeck ◽  
Florence Gazeau ◽  
Delphine El Kharrat ◽  
Olivier Sandre ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document