Verification of specific G-quadruplex structure by using a novel cyanine dye supramolecular assembly: I. Recognizing mixed G-quadruplex in human telomeres

2009 ◽  
pp. 1103 ◽  
Author(s):  
Qianfan Yang ◽  
Junfeng Xiang ◽  
Shu Yang ◽  
Qiuju Zhou ◽  
Qian Li ◽  
...  
Keyword(s):  
Supramolecular Assembly ◽  
Cyanine Dye ◽  
Quadruplex Structure ◽  
G Quadruplex

Reversible regulation of the supramolecular chirality of a cyanine dye by using the G-quadruplex structure as a template

2016 ◽  
Vol 52 (45) ◽  
pp. 7302-7305 ◽  
Author(s):  
Yunhua Shi ◽  
Hongxia Sun ◽  
Junfeng Xiang ◽  
Hongbo Chen ◽  
Suge Zhang ◽  
...  
Keyword(s):  
Cyanine Dye ◽  
Quadruplex Structure ◽  
Supramolecular Chirality ◽  
G Quadruplex ◽  
Multiple Cycle ◽  
Cycle Regulation

Multiple cycle regulation of the supramolecular chirality of a cyanine dye has been successfully achieved by using DNA G-quadruplexes as templates, which is easily controllable by repeated addition of Ag+ and cysteine (Cys).

Targeting of parallel c-myc G-quadruplex by dimeric cyanine dye supramolecular assembly: dependence on the linker length

The Analyst ◽  
2015 ◽  
Vol 140 (5) ◽  
pp. 1637-1646 ◽  
Author(s):  
Lijia Yu ◽  
Qianfan Yang ◽  
Junfeng Xiang ◽  
Hongxia Sun ◽  
Lixia Wang ◽  
...  
Keyword(s):  
Supramolecular Assembly ◽  
Cyanine Dyes ◽  
Cyanine Dye ◽  
Linker Length ◽  
G Quadruplex

The recognizing ability of parallel c-myc G-quadruplex by dimeric cyanine dyes depends on their linker length.

scholarly journals Disassembly of Dimeric Cyanine Dye Supramolecular Assembly by Tetramolecular G-quadruplex Dependence on Linker Length and Layers of G-quartet

Molecules ◽  
2019 ◽  
Vol 24 (10) ◽  
pp. 2015 ◽  
Author(s):  
Lijia Yu ◽  
Yansong Zhang ◽  
Chunguang Ding ◽  
Xiaodong Shi
Keyword(s):  
Supramolecular Assembly ◽  
Cyanine Dyes ◽  
Binding Mode ◽  
Cyanine Dye ◽  
Linker Length ◽  
Disassembly Process ◽  
1H Nmr Titration ◽  
Repeat Units ◽  
G Quadruplex ◽  
Photochemical Properties

Cyanine dyes have been widely applied in various biological systems owing to their specific photochemical properties. Assembly and disassembly process of cyanine dyes were constructed and regulated by special biomolecules. In this paper, dimeric cyanine dyes with different repeat units (oligo-oxyethylene) in linker (TC-Pn) (n = 3–6) were found to form H-aggregates or mixture aggregates in PBS. These aggregates could be disassembled into dimer and/or monomer by (TGnT) tetramolecular G-quadruplexes (n = 3–6, 8), which were affected by the linker length of dimeric cyanine dyes and layers of G-quartets. The 1H-NMR titration results suggest that the binding mode of dimeric cyanine dye with TGnT might be on both ends—stacking like a clip. This binding mode could clearly explain that matching structures between dimeric cyanine dyes and TGnT quadruplexes could regulate the disassembly properties of aggregates. These results could provide clues for the development of highly specific G-quadruplex probes.

A cyanine dye supramolecular FRET switch driven by G-quadruplex to monitor mitophagy

2021 ◽  
pp. 109429
Author(s):  
Xiaomeng Guo ◽  
Dawei Yang ◽  
Ranran Sun ◽  
Qian Li ◽  
Hongyan Du ◽  
...  
Keyword(s):  
Cyanine Dye ◽  
G Quadruplex
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