Interfacing reversed-phase nanoHPLC with ICP-MS and on-line isotope dilution analysis for the accurate quantification of selenium-containing peptides in protein tryptic digests

2005 ◽  
Vol 20 (10) ◽  
pp. 1101 ◽  
Author(s):  
Pierre Giusti ◽  
Dirk Schaumlöffel ◽  
Jorge Ruiz Encinar ◽  
Joanna Szpunar
Keyword(s):  
Isotope Dilution ◽  
Reversed Phase ◽  
Isotope Dilution Analysis ◽  
Icp Ms ◽  
On Line ◽  
Accurate Quantification

Quantitation of the Fe spatial distribution in biological tissue by online double isotope dilution analysis with LA-ICP-MS: a strategy for estimating measurement uncertainty

2016 ◽  
Vol 31 (1) ◽  
pp. 270-279 ◽  
Author(s):  
David N. Douglas ◽  
Jennifer O'Reilly ◽  
Ciaran O'Connor ◽  
Barry L. Sharp ◽  
Heidi Goenaga-Infante
Keyword(s):  
Spatial Distribution ◽  
Quantitative Analysis ◽  
Laser Ablation ◽  
Measurement Uncertainty ◽  
Isotope Dilution ◽  
Biological Tissue ◽  
Isotope Dilution Analysis ◽  
Icp Ms ◽  
On Line ◽  
Double Isotope

A strategy, systematically developed, is reported for the quantitative analysis of the Fe spatial distribution in biological tissue using laser ablation with ICP-MS and on-line double isotope dilution analysis.

scholarly journals On-line reverse isotope dilution analysis for spatial quantification of elemental labels used in immunohistochemical assisted imaging mass spectrometry via LA-ICP-MS

2019 ◽  
Vol 34 (2) ◽  
pp. 407-412 ◽  
Author(s):  
David Clases ◽  
Raquel Gonzalez de Vega ◽  
Paul A. Adlard ◽  
Philip A. Doble
Keyword(s):  
Mass Spectrometry ◽  
Isotope Dilution ◽  
Imaging Mass Spectrometry ◽  
Isotope Dilution Analysis ◽  
Icp Ms ◽  
On Line

We present a novel on-line isotope dilution analysis (IDA) approach for the quantification of isotopically enriched metal labels used in immunohistochemical assisted imaging mass spectrometry.

Automated On-Line Isotope Dilution Analysis with ICP-MS Using Sandwich Flow Injection

1998 ◽  
Vol 70 (5) ◽  
pp. 1036-1040 ◽  
Author(s):  
August A. Specht ◽  
Diane Beauchemin
Keyword(s):  
Flow Injection ◽  
Isotope Dilution ◽  
Isotope Dilution Analysis ◽  
Icp Ms ◽  
On Line

scholarly journals SEC-ICP-MS and on-line isotope dilution analysis for characterisation and quantification of immunochemical assays

2019 ◽  
Vol 411 (16) ◽  
pp. 3553-3560 ◽  
Author(s):  
David Clases ◽  
Raquel Gonzalez de Vega ◽  
David Bishop ◽  
Philip Doble
Keyword(s):  
Isotope Dilution ◽  
Isotope Dilution Analysis ◽  
Icp Ms ◽  
On Line

Correction of mass fractionation for isotope dilution analysis by MC-ICP-MS

2017 ◽  
Vol 51 (2) ◽  
pp. 157-165
Author(s):  
Le Zhang ◽  
Zhong-Yuan Ren ◽  
Jin-Long Ma ◽  
Xiao-Ping Xia
Keyword(s):  
Isotope Dilution ◽  
Isotope Dilution Analysis ◽  
Mass Fractionation ◽  
Icp Ms

An approach for quantification of platinum distribution in tissues by LA-ICP-MS imaging using isotope dilution analysis

Talanta ◽  
2018 ◽  
Vol 178 ◽  
pp. 166-171 ◽  
Author(s):  
I. Moraleja ◽  
M.L. Mena ◽  
A. Lázaro ◽  
B. Neumann ◽  
A. Tejedor ◽  
...  
Keyword(s):  
Isotope Dilution ◽  
Isotope Dilution Analysis ◽  
Ms Imaging ◽  
Icp Ms

Accurate Quantification of Selenoprotein P (SEPP1) in Plasma Using Isotopically Enriched Seleno-peptides and Species-Specific Isotope Dilution with HPLC Coupled to ICP-MS/MS

2016 ◽  
Vol 88 (12) ◽  
pp. 6357-6365 ◽  
Author(s):  
Christian L. Deitrich ◽  
Susana Cuello-Nuñez ◽  
Diana Kmiotek ◽  
Frank Attila Torma ◽  
Maria Estela del Castillo Busto ◽  
...  
Keyword(s):  
Isotope Dilution ◽  
Selenoprotein P ◽  
Icp Ms ◽  
Species Specific ◽  
Accurate Quantification

Species-selective Analysis for Metal - Biomacromolecular Complexes using Hyphenated Techniques

1999 ◽  
Vol 71 (5) ◽  
pp. 899-918 ◽  
Author(s):  
J. Szpunar ◽  
R. Lobinski
Keyword(s):  
Mass Spectrometry ◽  
Inductively Coupled Plasma ◽  
Absorption Spectrometry ◽  
Reversed Phase ◽  
Size Exclusion ◽  
Emission Spectrometry ◽  
Hyphenated Techniques ◽  
Plasma Atomic Emission Spectrometry ◽  
Icp Ms ◽  
On Line

Analytical chemistry of metal complexes with biomacromolecules based on the coupling of a high resolution separation technique with an element or species selective detection technique is critically discussed. The role of size-exclusion chromatography (SEC) with on-line atomic spectrometric detection is evaluated for the characterization of the metal distribution among the fractions of different molecular weight. Attention is given to the conditions for the separation of metallated biomacromolecular isoforms and sub-isoforms by anion-exchange and reversed-phase HPLC. Techniques for interfacing chromatography with atomic absorption spectrometry (AAS), inductively coupled plasma atomic emission spectrometry (ICP AES) and ICP mass spectrometry (ICP MS) are assessed. The potential of electrospray (tandem) mass spectrometry for the on-line determination of the molecular mass of the eluting protein is highlighted. Perspectives for capillary zone electrophoresis (CZE), microbore and capillary HPLC with ICP MS and electrospray MS detection for probing metalloproteins are discussed. Applications of hyphenated techniques to the analysis of real-world samples are reviewed.

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