Interfacing reversed-phase nanoHPLC with ICP-MS and on-line isotope dilution analysis for the accurate quantification of selenium-containing peptides in protein tryptic digests

2005 ◽  
Vol 20 (10) ◽  
pp. 1101 ◽  
Author(s):  
Pierre Giusti ◽  
Dirk Schaumlöffel ◽  
Jorge Ruiz Encinar ◽  
Joanna Szpunar
2016 ◽  
Vol 31 (1) ◽  
pp. 270-279 ◽  
Author(s):  
David N. Douglas ◽  
Jennifer O'Reilly ◽  
Ciaran O'Connor ◽  
Barry L. Sharp ◽  
Heidi Goenaga-Infante

A strategy, systematically developed, is reported for the quantitative analysis of the Fe spatial distribution in biological tissue using laser ablation with ICP-MS and on-line double isotope dilution analysis.


2019 ◽  
Vol 34 (2) ◽  
pp. 407-412 ◽  
Author(s):  
David Clases ◽  
Raquel Gonzalez de Vega ◽  
Paul A. Adlard ◽  
Philip A. Doble

We present a novel on-line isotope dilution analysis (IDA) approach for the quantification of isotopically enriched metal labels used in immunohistochemical assisted imaging mass spectrometry.


1998 ◽  
Vol 70 (5) ◽  
pp. 1036-1040 ◽  
Author(s):  
August A. Specht ◽  
Diane Beauchemin

2019 ◽  
Vol 411 (16) ◽  
pp. 3553-3560 ◽  
Author(s):  
David Clases ◽  
Raquel Gonzalez de Vega ◽  
David Bishop ◽  
Philip Doble

2017 ◽  
Vol 51 (2) ◽  
pp. 157-165
Author(s):  
Le Zhang ◽  
Zhong-Yuan Ren ◽  
Jin-Long Ma ◽  
Xiao-Ping Xia

Talanta ◽  
2018 ◽  
Vol 178 ◽  
pp. 166-171 ◽  
Author(s):  
I. Moraleja ◽  
M.L. Mena ◽  
A. Lázaro ◽  
B. Neumann ◽  
A. Tejedor ◽  
...  

2016 ◽  
Vol 88 (12) ◽  
pp. 6357-6365 ◽  
Author(s):  
Christian L. Deitrich ◽  
Susana Cuello-Nuñez ◽  
Diana Kmiotek ◽  
Frank Attila Torma ◽  
Maria Estela del Castillo Busto ◽  
...  

1999 ◽  
Vol 71 (5) ◽  
pp. 899-918 ◽  
Author(s):  
J. Szpunar ◽  
R. Lobinski

Analytical chemistry of metal complexes with biomacromolecules based on the coupling of a high resolution separation technique with an element or species selective detection technique is critically discussed. The role of size-exclusion chromatography (SEC) with on-line atomic spectrometric detection is evaluated for the characterization of the metal distribution among the fractions of different molecular weight. Attention is given to the conditions for the separation of metallated biomacromolecular isoforms and sub-isoforms by anion-exchange and reversed-phase HPLC. Techniques for interfacing chromatography with atomic absorption spectrometry (AAS), inductively coupled plasma atomic emission spectrometry (ICP AES) and ICP mass spectrometry (ICP MS) are assessed. The potential of electrospray (tandem) mass spectrometry for the on-line determination of the molecular mass of the eluting protein is highlighted. Perspectives for capillary zone electrophoresis (CZE), microbore and capillary HPLC with ICP MS and electrospray MS detection for probing metalloproteins are discussed. Applications of hyphenated techniques to the analysis of real-world samples are reviewed.


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