Chemical and physical processes for integrated temperature control in microfluidic devices

Lab on a Chip ◽  
2003 ◽  
Vol 3 (1) ◽  
pp. 1 ◽  
Author(s):  
Rosanne M. Guijt ◽  
Arash Dodge ◽  
Gijs W. K. van Dedem ◽  
Nico F. de Rooij ◽  
Elisabeth Verpoorte
2002 ◽  
pp. 617-619
Author(s):  
A. Dodge ◽  
R. M. Guijt ◽  
G. W. K. van Dedem ◽  
N. F. de Rooij ◽  
E. Verpoorte

Soft Matter ◽  
2019 ◽  
Vol 15 (35) ◽  
pp. 6934-6937 ◽  
Author(s):  
Toshimitsu Kanai ◽  
Hiroki Nakai ◽  
Ayaka Yamada ◽  
Masafumi Fukuyama ◽  
David A. Weitz

We report a facile method for preparing monodisperse hybrid smart gel particles with various morphologies by using microfluidic devices.


2013 ◽  
Vol 795 ◽  
pp. 459-463 ◽  
Author(s):  
Shahrul A.B. Ariffin ◽  
U. Hashim ◽  
Tijjani Adam

Microfluidic devices present a powerful platform for working with living cells and even gases. Parameter such as the length and volume scales of these devices in miniaturize system makes it possible to develops and perform detailed analyses with several advantages. The objective of this project is to do a design of 1μm microfluidic separator device that consist the microchannel. Furthermore, another objective is to understand the fundamental physical processes of fluid flow in these devices and to predict their behavior and every method using in the simulation of COMSOL Multiphysics 3.5 software will be elaborate in numerical simulation technique section. Finally, result from the simulation such as concentration, fluidic flow pressure and velocity field will be observed and explained in the result section.


Micromachines ◽  
2021 ◽  
Vol 12 (10) ◽  
pp. 1149
Author(s):  
Violeta Carvalho ◽  
Raquel O. Rodrigues ◽  
Rui A. Lima ◽  
Senhorinha Teixeira

Numerical simulations have revolutionized research in several engineering areas by contributing to the understanding and improvement of several processes, being biomedical engineering one of them. Due to their potential, computational tools have gained visibility and have been increasingly used by several research groups as a supporting tool for the development of preclinical platforms as they allow studying, in a more detailed and faster way, phenomena that are difficult to study experimentally due to the complexity of biological processes present in these models—namely, heat transfer, shear stresses, diffusion processes, velocity fields, etc. There are several contributions already in the literature, and significant advances have been made in this field of research. This review provides the most recent progress in numerical studies on advanced microfluidic devices, such as organ-on-a-chip (OoC) devices, and how these studies can be helpful in enhancing our insight into the physical processes involved and in developing more effective OoC platforms. In general, it has been noticed that in some cases, the numerical studies performed have limitations that need to be improved, and in the majority of the studies, it is extremely difficult to replicate the data due to the lack of detail around the simulations carried out.


Lab on a Chip ◽  
2012 ◽  
Vol 12 (1) ◽  
pp. 127-132 ◽  
Author(s):  
Daniel C. Leslie ◽  
Erkin Seker ◽  
Lindsay A. L. Bazydlo ◽  
Briony C. Strachan ◽  
James P. Landers

Lab on a Chip ◽  
2004 ◽  
Vol 4 (5) ◽  
pp. 417 ◽  
Author(s):  
Andrew J. de Mello ◽  
Matthew Habgood ◽  
N. Llewellyn Lancaster ◽  
Tom Welton ◽  
Robert C. R. Wootton

1979 ◽  
Vol 44 ◽  
pp. 349-355
Author(s):  
R.W. Milkey

The focus of discussion in Working Group 3 was on the Thermodynamic Properties as determined spectroscopically, including the observational techniques and the theoretical modeling of physical processes responsible for the emission spectrum. Recent advances in observational techniques and theoretical concepts make this discussion particularly timely. It is wise to remember that the determination of thermodynamic parameters is not an end in itself and that these are interesting chiefly for what they can tell us about the energetics and mass transport in prominences.


Author(s):  
P.R. Swann ◽  
A.E. Lloyd

Figure 1 shows the design of a specimen stage used for the in situ observation of phase transformations in the temperature range between ambient and −160°C. The design has the following features a high degree of specimen stability during tilting linear tilt actuation about two orthogonal axes for accurate control of tilt angle read-out high angle tilt range for stereo work and habit plane determination simple, robust construction temperature control of better than ±0.5°C minimum thermal drift and transmission of vibration from the cooling system.


Author(s):  
Randall W. Smith ◽  
John Dash

The structure of the air-water interface forms a boundary layer that involves biological ,chemical geological and physical processes in its formation. Freshwater and sea surface microlayers form at the air-water interface and include a diverse assemblage of organic matter, detritus, microorganisms, plankton and heavy metals. The sampling of microlayers and the examination of components is presently a significant area of study because of the input of anthropogenic materials and their accumulation at the air-water interface. The neustonic organisms present in this environment may be sensitive to the toxic components of these inputs. Hardy reports that over 20 different methods have been developed for sampling of microlayers, primarily for bulk chemical analysis. We report here the examination of microlayer films for the documentation of structure and composition.Baier and Gucinski reported the use of Langmuir-Blogett films obtained on germanium prisms for infrared spectroscopic analysis (IR-ATR) of components. The sampling of microlayers has been done by collecting fi1ms on glass plates and teflon drums, We found that microlayers could be collected on 11 mm glass cover slips by pulling a Langmuir-Blogett film from a surface microlayer. Comparative collections were made on methylcel1ulose filter pads. The films could be air-dried or preserved in Lugol's Iodine Several slicks or surface films were sampled in September, 1987 in Chesapeake Bay, Maryland and in August, 1988 in Sequim Bay, Washington, For glass coverslips the films were air-dried, mounted on SEM pegs, ringed with colloidal silver, and sputter coated with Au-Pd, The Langmuir-Blogett film technique maintained the structure of the microlayer intact for examination, SEM observation and EDS analysis were then used to determine organisms and relative concentrations of heavy metals, using a Link AN 10000 EDS system with an ISI SS40 SEM unit. Typical heavy microlayer films are shown in Figure 3.


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