Towards the development of molecularly imprinted artificial receptors for the screening of estrogenic chemicals

The Analyst ◽  
2001 ◽  
Vol 126 (6) ◽  
pp. 760-765 ◽  
Author(s):  
Lei Ye ◽  
Yihua Yu ◽  
Klaus Mosbach
Keyword(s):  
Molecularly Imprinted ◽  
Artificial Receptors ◽  
Estrogenic Chemicals

Application of molecularly imprinted polymers as artificial receptors for imaging

2020 ◽  
Vol 101 ◽  
pp. 444-458 ◽  
Author(s):  
Tereza Vaneckova ◽  
Jaroslava Bezdekova ◽  
Gang Han ◽  
Vojtech Adam ◽  
Marketa Vaculovicova
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Artificial Receptors

scholarly journals Molecularly Imprinted Polymers and Surface Imprinted Polymers Based Electrochemical Biosensor for Infectious Diseases

Sensors ◽  
2020 ◽  
Vol 20 (4) ◽  
pp. 996 ◽  
Author(s):  
Feiyun Cui ◽  
Zhiru Zhou ◽  
H. Susan Zhou
Keyword(s):  
Infectious Diseases ◽  
Molecularly Imprinted Polymers ◽  
Low Cost ◽  
Electrochemical Biosensors ◽  
Critical Element ◽  
Preparation Methods ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Artificial Receptors ◽  
Stability And Accuracy

Owing to their merits of simple, fast, sensitive, and low cost, electrochemical biosensors have been widely used for the diagnosis of infectious diseases. As a critical element, the receptor determines the selectivity, stability, and accuracy of the electrochemical biosensors. Molecularly imprinted polymers (MIPs) and surface imprinted polymers (SIPs) have great potential to be robust artificial receptors. Therefore, extensive studies have been reported to develop MIPs/SIPs for the detection of infectious diseases with high selectivity and reliability. In this review, we discuss mechanisms of recognition events between imprinted polymers with different biomarkers, such as signaling molecules, microbial toxins, viruses, and bacterial and fungal cells. Then, various preparation methods of MIPs/SIPs for electrochemical biosensors are summarized. Especially, the methods of electropolymerization and micro-contact imprinting are emphasized. Furthermore, applications of MIPs/SIPs based electrochemical biosensors for infectious disease detection are highlighted. At last, challenges and perspectives are discussed.

scholarly journals Determination of sitagliptin in human plasma using a smart electrochemical sensor based on electroactive molecularly imprinted nanoparticles

2021 ◽  
Author(s):  
Isma Haq ◽  
Kaseb D.M. Alanazi ◽  
Joanna Czulak ◽  
Sabrina Di Masi ◽  
Elena Piletska ◽  
...  
Keyword(s):  
Electrochemical Sensor ◽  
Molecularly Imprinted Polymer ◽  
Polymer Nanoparticles ◽  
Voltammetric Sensor ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Redox Probe ◽  
Artificial Receptors ◽  
Molecularly Imprinted Nanoparticles

A sitagliptin voltammetric sensor was fabricated using artificial receptors called electroactive molecularly imprinted polymer nanoparticles (nanoMIP). The nanoMIP tagged with a redox probe (ferrocene) combines both the recognition and reporting...

scholarly journals Biomimetic Sensors to Detect Bioanalytes in Real-Life Samples Using Molecularly Imprinted Polymers: A Review

Sensors ◽  
2021 ◽  
Vol 21 (16) ◽  
pp. 5550 ◽  
Author(s):  
Birgit Bräuer ◽  
Christine Unger ◽  
Martin Werner ◽  
Peter A. Lieberzeit
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Large Body ◽  
Real Life ◽  
Biological Species ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Artificial Receptors ◽  
Main Emphasis ◽  
Research Stage ◽  
Transducer Type

Molecularly imprinted polymers (MIPs) come with the promise to be highly versatile, useful artificial receptors for sensing a wide variety of analytes. Despite a very large body of literature on imprinting, the number of papers addressing real-life biological samples and analytes is somewhat limited. Furthermore, the topic of MIP-based sensor design is still, rather, in the research stage and lacks wide-spread commercialization. This review summarizes recent advances of MIP-based sensors targeting biological species. It covers systems that are potentially interesting in medical applications/diagnostics, in detecting illicit substances, environmental analysis, and in the quality control of food. The main emphasis is placed on work that demonstrates application in real-life matrices, including those that are diluted in a reasonable manner. Hence, it does not restrict itself to the transducer type, but focusses on both materials and analytical tasks.

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