scholarly journals Label-free Detection of Influenza Viruses using a Reduced Graphene Oxide-based Electrochemical Immunosensor Integrated with a Microfluidic Platform

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Renu Singh ◽  
Seongkyeol Hong ◽  
Jaesung Jang
The Analyst ◽  
2021 ◽  
Author(s):  
Xinke Liu ◽  
Lu-Yin Lin ◽  
Fu-Yen Tseng ◽  
Yu-Cheng Tan ◽  
Jian Li ◽  
...  

Matrix metalloproteinase-1 (MMP-1) is associated with many types of cancers, including oral, colorectal, and brain cancers. This paper describes the fabrication of an MMP-1 immunosensor based on a gold nanoparticle/polyethyleneimine/reduced...


Carbon ◽  
2021 ◽  
Vol 179 ◽  
pp. 514-522
Author(s):  
Jagriti Sethi ◽  
Ahmed Suhail ◽  
Mina Safarzadeh ◽  
Anas Sattar ◽  
Yinghui Wei ◽  
...  

2021 ◽  
Vol 9 ◽  
Author(s):  
Supakeit Chanarsa ◽  
Jaroon Jakmunee ◽  
Kontad Ounnunkad

A bi-functional material based on silver nanoparticles (AgNPs)-reduced graphene oxide (rGO) composite for both electrode modification and signal generation is successfully synthesized for use in the construction of a label-free electrochemical immunosensor. An AgNPs/rGO nanocomposite is prepared by a one-pot wet chemical process. The AgNPs/rGO composite dispersion is simply cast on a screen-printed carbon electrode (SPCE) to fabricate the electrochemical immunosensor. It possesses a sufficient conductivity/electroreactivity and improves the electrode reactivity of SPCE. Moreover, the material can generate an analytical response due to the formation of immunocomplexes for detection of human immunoglobulin G (IgG), a model biomarker. Based on electrochemical stripping of AgNPs, the material reveals signal amplification without external redox molecules/probes. Under optimized conditions, the square wave voltammetric peak current is responded to the logarithm of IgG concentration in two wide linear ranges from 1 to 50 pg.ml−1 and 0.05 to 50 ng.ml−1, and the limit of detection (LOD) is estimated to be 0.86 pg.ml−1. The proposed immunosensor displays satisfactory sensitivity and selectivity. Importantly, detection of IgG in human serum using the immunosensor shows satisfactory accuracy, suggesting that the immunosensor possesses a huge potential for further development in clinical diagnosis.


2016 ◽  
Vol 8 (40) ◽  
pp. 7380-7386 ◽  
Author(s):  
Lihui Tian ◽  
Li Liu ◽  
Yueyuan Li ◽  
Xue Feng ◽  
Qin Wei ◽  
...  

A novel label-free electrochemical immunosensor based on trimetallic NiAuPt nanoparticles on reduced graphene oxide nanosheets (NiAuPt–NGs) was developed for the quantitative detection of hepatitis B surface antigen (HBsAg).


RSC Advances ◽  
2014 ◽  
Vol 4 (5) ◽  
pp. 2267-2273 ◽  
Author(s):  
Vinod Kumar ◽  
Saurabh Srivastava ◽  
Sima Umrao ◽  
Ram Kumar ◽  
Gopal Nath ◽  
...  

ACS Nano ◽  
2014 ◽  
Vol 8 (3) ◽  
pp. 2632-2638 ◽  
Author(s):  
Bingjie Cai ◽  
Shuting Wang ◽  
Le Huang ◽  
Yong Ning ◽  
Zhiyong Zhang ◽  
...  

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